Identification of Potential Key Genes in the Pathogenesis of Chronic Obstructive Pulmonary Disease Through Bioinformatics Analysis

Three hematologic/immune system-specific expressed genes are considered as the potential biomarkers for the diagnosis of early rheumatoid arthritis through bioinformatics analysis

(2021) Qi Cheng et al.   Journal of Translational Medicine

CD86 Molecule Might Be a Novel Immune-Related Prognostic Biomarker for Patients With Bladder Cancer by Bioinformatics and Experimental Assays

(2021) Xin Yan et al.   Frontiers in Oncology

Exploring the Pharmacological Mechanism of Radix Salvia Miltiorrhizae in the Treatment of Radiation Pneumonia by Using Network Pharmacology

(2021) Peng Li et al.   Frontiers in Oncology

Bioinformatics and Immune Infiltration Analyses Reveal the Key Pathway and Immune Cells in the Pathogenesis of Hypertrophic Cardiomyopathy

(2021) Xu-Zhe Zhang et al.   Frontiers in Cardiovascular Medicine

Targeting defective pulmonary innate immunity – A new therapeutic option?

(2020) Kylie B.R. Belchamber et al.   PHARMACOLOGY & THERAPEUTICS

Cigarette smoke-induced lung inflammation in COPD mediated via CCR1/JAK/STAT /NF-κB pathway

(2020) Kaishun Zhao et al.   Aging-US

Increased von Willebrand Factor Processing in COPD, Reflecting Lung Epithelium Damage, Is Associated with Emphysema, Exacerbations and Elevated Mortality Risk

(2020) Lasse L Langholm et al.   International Journal of Chronic Obstructive Pulmonary Disease

The PI3K/AKT/mTOR pathway regulates autophagy to induce apoptosis of alveolar epithelial cells in chronic obstructive pulmonary disease caused by PM2.5 particulate matter

(2020) Fang Zhang et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

2011 GOLD Stages of COPD: Transitions, Predictor Factors and Comparison with 2017 GOLD Stages

(2020) Roberto Bernabeu-Mora et al.   International Journal of Chronic Obstructive Pulmonary Disease

The roles of endothelin and its receptors in cigarette smoke-associated pulmonary hypertension with chronic lung disease

(2020) Yaping Zhang et al.   PATHOLOGY RESEARCH AND PRACTICE

PTPLAD2 and USP49 Involved in the Pathogenesis of Smoke-Induced COPD by Integrative Bioinformatics Analysis

(2020) Qiang Zhang et al.   International Journal of Chronic Obstructive Pulmonary Disease

Evaluation of Naringenin as a Promising Treatment Option for COPD Based on Literature Review and Network Pharmacology

(2020) Zhen Chen et al.   Biomolecules

Bufei Jianpi Granules Reduce Quadriceps Muscular Cell Apoptosis by Improving Mitochondrial Function in Rats with Chronic Obstructive Pulmonary Disease

(2019) Jing Mao et al.   Evidence-based Complementary and Alternative Medicine

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease: The GOLD Science Committee Report 2019

(2019) Dave Singh et al.   EUROPEAN RESPIRATORY JOURNAL

Effect of Bufei Yishen Granules Combined with Electroacupuncture in Rats with Chronic Obstructive Pulmonary Disease via the Regulation of TLR-4/NF-κB Signaling

(2019) Jindi Ma et al.   Evidence-based Complementary and Alternative Medicine

A Pan-cancer Transcriptome Analysis Reveals Pervasive Regulation through Alternative Promoters

(2019) Deniz Demircioğlu et al.   CELL

Mitochondrial dysfunction in macrophages: a key to defective bacterial phagocytosis in COPD

(2019) Mathew Suji Eapen et al.   EUROPEAN RESPIRATORY JOURNAL

Association between glutathione S-transferase gene M1 and T1 polymorphisms and chronic obstructive pulmonary disease risk: A meta-analysis

(2018) Z. Ding et al.   CLINICAL GENETICS

Lung Macrophage Phenotypes and Functional Responses: Role in the Pathogenesis of COPD

(2018) Kei Yamasaki et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transcriptional signature associated with early rheumatoid arthritis and healthy individuals at high risk to develop the disease

(2018) N. Macías-Segura et al.   PLoS One

Identification of differentially expressed genes in synovial tissue of rheumatoid arthritis and osteoarthritis in patients

(2018) Wen Chao Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

miRNA-206 regulates human pulmonary microvascular endothelial cell apoptosis via targeting in chronic obstructive pulmonary disease

(2018) Ying Sun et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Transcriptome Analysis of Recurrently Deregulated Genes across Multiple Cancers Identifies New Pan-Cancer Biomarkers

(2015) Bogumil Kaczkowski et al.   CANCER RESEARCH

Accelerated ageing of the lung in COPD: new concepts

(2015) Nicolas Mercado et al.   THORAX

Comprehensive Analysis of Transcriptome Sequencing Data in the Lung Tissues of COPD Subjects

(2015) Woo Jin Kim et al.   International Journal of Genomics

Burden of asthma and chronic obstructive pulmonary disease and access to essential medicines in low-income and middle-income countries

(2015) David Beran et al.   Lancet Respiratory Medicine

cytoHubba: identifying hub objects and sub-networks from complex interactome

(2014) Chia-Hao Chin et al.   BMC Systems Biology

Association between the IL1B, IL1RN polymorphisms and COPD risk: A meta-analysis

(2014) Zi-Kang Xie et al.   Scientific Reports

Continuing to Confront COPD International Patient Survey: methods, COPD prevalence, and disease burden in 2012–2013

(2014) Kate Hollingworth et al.   International Journal of Chronic Obstructive Pulmonary Disease

Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis

(2014) Michael H Cho et al.   Lancet Respiratory Medicine

starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data

(2013) Jun-Hao Li et al.   NUCLEIC ACIDS RESEARCH

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease

(2012) Jørgen Vestbo et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A Rat Model for Stable Chronic Obstructive Pulmonary Disease Induced by Cigarette Smoke Inhalation and Repetitive Bacterial Infection

(2012) Ya Li et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Defective Phagocytosis in Airways Disease

(2012) Louise E. Donnelly et al.   CHEST

Effect of Five Genetic Variants Associated with Lung Function on the Risk of Chronic Obstructive Lung Disease, and Their Joint Effects on Lung Function

(2011) María Soler Artigas et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

(2011) Leonardo Salmena et al.   CELL

Lifetime risk of developing chronic obstructive pulmonary disease: a longitudinal population study

(2011) Andrea S Gershon et al.   LANCET

Variants in FAM13A are associated with chronic obstructive pulmonary disease

(2010) Michael H Cho et al.   NATURE GENETICS

The 15q24/25 Susceptibility Variant for Lung Cancer and Chronic Obstructive Pulmonary Disease Is Associated with Emphysema

(2009) Diether Lambrechts et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Genome-wide association study identifies five loci associated with lung function

(2009) Emmanouela Repapi et al.   NATURE GENETICS

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

(2009) Dana B Hancock et al.   NATURE GENETICS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

MMP12,Lung Function, and COPD in High-Risk Populations

(2009) Gary M. Hunninghake et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci

(2009) Sreekumar G. Pillai et al.   PLoS Genetics

High levels of Epstein-Barr virus in COPD

(2008) T. E. McManus et al.   EUROPEAN RESPIRATORY JOURNAL