Article
Public, Environmental & Occupational Health
Christopher A. Taylor, Michael Whitaker, Onika Anglin, Jennifer Milucky, Kadam Patel, Huong Pham, Shua J. Chai, Nisha B. Alden, Kimberly Yousey-Hindes, Evan J. Anderson, Kenzie Teno, Libby Reeg, Kathryn Como-Sabetti, Molly Bleecker, Grant Barney, Nancy M. Bennett, Laurie M. Billing, Melissa Sutton, H. Keipp Talbot, Keegan McCaffrey, Fiona P. Havers
Summary: This report provides data on hospitalization rates among adults during the Omicron-dominant period, showing a significant increase in weekly COVID-19-associated hospitalization rates.
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
(2022)
Article
Immunology
Ivan Martinez-Baz, Miguel Fernandez-Huerta, Ana Navascues, Francisco Pozo, Camino Trobajo-Sanmartin, Itziar Casado, Aitziber Echeverria, Carmen Ezpeleta, Jesus Castilla
Summary: This study estimated the effectiveness of the influenza vaccine in preventing outpatient and hospitalized cases in the 2022-2023 season. The results showed that the vaccine was effective against influenza B, moderately effective against A(H3N2), and ineffective against A(H1N1). The effectiveness of the vaccine was lower in hospitalized patients compared to outpatients, possibly due to a lower proportion of influenza B cases. The null effectiveness against A(H1N1) was consistent with antigenic drift and supported the use of a new composition for the 2023-2024 influenza vaccine.
Letter
Medicine, General & Internal
Alaleh Azhir, Zachary H. Strasser, Shawn N. Murphy, Hossein Estiri
Summary: This study creates a temporal profile of the severity of COVID-19 in Massachusetts from July 2021 to December 2022 using hospitalization and 30-day mortality risks.
Article
Immunology
Jeremy A. W. Gold, Stacey Adjei, Adi V. Gundlapalli, Ya-Lin A. Huang, Tom Chiller, Kaitlin Benedict, Mitsuru Toda
Summary: Hospitalizations due to fungal infections in the US increased by 8.5% annually from 2019 to 2021. In 2020-2021, patients hospitalized with COVID-19-associated fungal infections had a higher in-hospital mortality rate (48.5%) compared to those with non-COVID-19-associated fungal infections (12.3%). Enhanced surveillance of fungal diseases is necessary, especially during respiratory virus pandemics.
EMERGING INFECTIOUS DISEASES
(2023)
Article
Public, Environmental & Occupational Health
Erin L. Winkler, Shauna L. Stahlman, Natalie Y. Wells, Aparna V. Chauhan, Kayli M. Hiban, Amy A. Costello, James D. Mancuso
Summary: A study found that the uptake of COVID-19 booster vaccine among U.S. military servicemembers was lower compared to the general U.S. population. The vaccine uptake was associated with factors such as age, education level, income, gender, and overseas deployment. Additionally, previous COVID-19 infection and use of the Janssen vaccine were associated with lower booster vaccine uptake. The low vaccination rates increase the risk of COVID-19 health effects among servicemembers and affect the overall readiness of the U.S. military.
AMERICAN JOURNAL OF PREVENTIVE MEDICINE
(2023)
Article
Public, Environmental & Occupational Health
Christopher A. Taylor, Kadam Patel, Monica E. Patton, Arthur Reingold, Breanna Kawasaki, James Meek, Kyle Openo, Patricia A. Ryan, Anna Falkowski, Erica Bye, Kelly Plymesser, Nancy Spina, Brenda L. Tesini, Nancy E. Moran, Melissa Sutton, H. Keipp Talbot, Andrea George, Fiona P. Havers
Summary: Adults aged >= 65 years have a significantly higher risk of severe COVID-19 disease and associated hospitalizations compared to younger age groups. Data analysis shows that hospitalization rates for this age group more than doubled from January to August 2023. The majority of hospitalized adults in this age group had underlying health conditions and a low percentage had received the recommended COVID-19 vaccine.
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
(2023)
Article
Immunology
Roni Biran, Regev Cohen, Talya Finn, Tal Brosh-Nissimov, Galia Rahav, Dafna Yahav, Sharon Amit, Yael Shachor-Meyouhas, Alaa Atamna, Jihad Bishara, Liat Ashkenazi-Hoffnung, Haim Ben Zvi, Mirit Hershman-Sarafov, Shlomo Maayan, Yasmin Maor, Orna Schwartz, Oren Zimhony, Jonathan Lellouche, Meital Elbaz, Ela Burdelova, Naama Mizrahi, Anna Novikov, Oryan Henig, Ronen Ben-Ami
Summary: We present a report on the outbreak of Candida auris in multiple healthcare facilities in Israel. A total of 209 patients with C. auris infection or colonization were identified from May 2014 to May 2022. The incidence rate of C. auris increased significantly in 2021, coinciding with the surge of COVID-19 hospitalizations. Outbreaks occurred at the hospital level with distinct clones, and a clade III clone, imported in 2016, accounted for a high proportion of isolates after January 2021 and exhibited higher resistance to fluconazole and voriconazole compared to non-clade III isolates. 23% of patients had COVID-19, and the outbreaks initially affected mechanically ventilated patients in specialized COVID-19 units before spreading to non-COVID-19 patients and nonventilated patients.
EMERGING INFECTIOUS DISEASES
(2023)
Article
Medicine, General & Internal
Nico Dragano, Olga Dortmann, Joerg Timm, Matthias Mohrmann, Rosemarie Wehner, Christoph J. Rupprecht, Maria Scheider, Ertan Mayatepek, Morten Wahrendorf
Summary: This population-based cohort study found that children from disadvantaged households have a higher risk of COVID-19 hospitalization. This highlights the need to pay attention to children from vulnerable families and consider closer monitoring. Although some explanatory factors were taken into account, no clear conclusion was drawn about the underlying processes.
Article
Immunology
Shannon C. O'Brien, Lyndsey D. Cole, Bernadette A. Albanese, Allison Mahon, Vijaya Knight, Nathan Williams, Rachel Severson, Alexis Burakoff, Nisha B. Alden, Samuel R. Dominguez
Summary: A cross-sectional sero-survey conducted in Colorado, USA, compared SARS-CoV-2 antibody seroprevalence among children with seropositive confirmed COVID-19 case counts. The survey found that seroprevalence was 36.7% among 829 Colorado children, higher than the reported prevalence of 6.5% based on COVID-19 test results. Racial/ethnic disparities in infections and case ascertainment were observed, with higher seroprevalence among Hispanic, non-Hispanic Black, and non-Hispanic children of other races, and lower case ascertainment among Hispanic and non-Hispanic Black children.
EMERGING INFECTIOUS DISEASES
(2023)
Article
Public, Environmental & Occupational Health
Vasco Ricoca Peixoto, Andre Vieira, Pedro Aguiar, Alexis Sentis, Carlos Carvalho, Daniel Rhys Thomas, Alexandre Abrantes, Carla Nunes
Summary: This study described the completeness of CN and EI in the Portuguese National Epidemiological Surveillance System and found a decrease in the submissions of CN and EI with an increase in COVID-19 cases after October 2020. By July 2021, a majority of cases had no associated CN or EI. Age and region were associated with the likelihood of having no CN or EI and no EI, with older age groups and certain regions having lower proportions.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Medicine, General & Internal
Fiona P. Havers, Huong Pham, Christopher A. Taylor, Michael Whitaker, Kadam Patel, Onika Anglin, Anita K. Kambhampati, Jennifer Milucky, Elizabeth Zell, Heidi L. Moline, Shua J. Chai, Pam Daily Kirley, Nisha B. Alden, Isaac Armistead, Kimberly Yousey-Hindes, James Meek, Kyle P. Openo, Evan J. Anderson, Libby Reeg, Alexander Kohrman, Ruth Lynfield, Kathryn Como-Sabetti, Elizabeth M. Davis, Cory Cline, Alison Muse, Grant Barney, Sophrena Bushey, Christina B. Felsen, Laurie M. Billing, Eli Shiltz, Melissa Sutton, Nasreen Abdullah, H. Keipp Talbot, William Schaffner, Mary Hill, Andrea George, Aron J. Hall, Stephanie R. Bialek, Neil C. Murthy, Bhavini Patel Murthy, Meredith McMorrow
Summary: Understanding the factors that contribute to hospitalization in vaccinated individuals is crucial for combating COVID-19. This study found that unvaccinated adults were more likely to be hospitalized compared to vaccinated adults, with the lowest hospitalization rates observed in those who had received a booster dose.
JAMA INTERNAL MEDICINE
(2022)
Article
Immunology
Erin N. O'Leary, Melinda M. Neuhauser, Arjun Srinivasan, Heather Dubendris, Amy K. Webb, Minn M. Soe, Lauri A. Hicks, Hsiu Wu, Sarah Kabbani, Jonathan R. Edwards
Summary: This study analyzed antimicrobial use data reported to the National Healthcare Safety Network's Antimicrobial Use and Resistance Module between January 2019 and July 2022 to assess the impact of the COVID-19 pandemic on inpatient antimicrobial use.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Infectious Diseases
Tobias Tenenbaum, Maren Doenhardt, Natalie Diffloth, Reinhard Berner, Jakob P. Armann
Summary: Public health measures implemented to mitigate the effects of the COVID-19 pandemic disrupted the worldwide transmission of endemic respiratory viruses such as RSV, as well as other typical, seasonal, and viral respiratory pathogens. German pediatric hospitals monitored RSV cases from October 18, 2021 to March 31, 2022 using a newly established national Clinician-Led Reporting System.
Article
Immunology
Brechje de Gier, Liselotte van Asten, Tjarda M. Boere, Annika van Roon, Caren van Roekel, Joyce Pijpers, C. H. Henri van Werkhoven, Caroline van den Ende, Susan J. M. Hahne, Hester E. de Melker, Mirjam J. Knol, Susan van den Hof
Summary: The COVID-19 vaccine has an effectiveness of over 90% in reducing COVID-19 mortality, and there is no increased risk of death from other causes due to vaccination.
Editorial Material
Medicine, General & Internal
Tom T. Shimabukuro, Matthew Cole, John R. Su
Summary: This JAMA Insights review provides clinical details of anaphylactic reactions reported to and verified by the CDC in the first month of use of the Pfizer-BioNTech and Moderna COVID-19 vaccines in the US, December 14, 2020-January 18, 2021.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2021)
