Article
Immunology
Motoya Kimura, Jun-Ichi Niwa, Manabu Doyu
Summary: Rhabdomyolysis following COVID-19 vaccination is a rare occurrence. This study reports a case of an elderly woman who developed recurring weakness and rhabdomyolysis after receiving the COVID-19 vaccine. Repeated MRI may be useful in predicting potential weakness and monitoring the course of vaccine-induced rhabdomyolysis.
Article
Immunology
Ariel Israel, Eugene Merzon, Yotam Shenhar, Ilan Green, Avivit Golan-Cohen, Alejandro A. Schaffer, Eytan Ruppin, Shlomo Vinker, Eli Magen
Summary: A population-based study in Israel found that individuals with chronic kidney disease and anemia had higher rates of COVID-19 infection within 14 days after booster vaccination.
Article
Immunology
Edrous Alamer, Abdulaziz Alhazmi, Naaif A. Qasir, Rahaf Alamer, Halima Areeshi, Gassem Gohal, Marwa Qadri, Anwar M. Hashem, Abdullah Algaissi
Summary: This study aimed to investigate the early side effects of the Pfizer-BioNTech (BNT162b2) mRNA vaccine in children aged 12-18 years in Saudi Arabia. Results showed that 60% of the participants reported at least one side effect, with pain or redness at the injection site, fatigue, fever, and headache being the most frequently reported. Female participants reported side effects more frequently than male participants, and side effects were more common after the second dose of the vaccine.
Article
Immunology
Samy Hakroush, Bjoern Tampe
Summary: Continuous monitoring of COVID-19 vaccine safety is crucial as vaccination programs expand worldwide, particularly in detecting rare adverse events associated with vaccination.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Takeharu Yoshikawa, Soichiro Miki, Takahiro Nakao, Saori Koshino, Naoto Hayashi, Osamu Abe
Summary: This study investigated the prevalence, predisposing factors, and MRI characteristics of COVID-19 vaccination-related axillary lymphadenopathy. It found that axillary lymphadenopathy was common within 2 weeks after vaccination, typically less than 10 mm in size, and had a normal apparent diffusion coefficient.
Article
Pediatrics
Sujeong Kim, Jiwon Jung, Haeyon Cho, Jina Lee, Heounjeong Go, Joo Hoon Lee
Summary: This is the first reported case of ANCA-negative CrGN after SARS-CoV-2 mRNA vaccination in the pediatric population. Monitoring for kidney complications should be warranted as children are increasingly vaccinated with SARS-CoV-2 mRNA vaccines.
PEDIATRIC NEPHROLOGY
(2023)
Article
Immunology
Rami Alqassieh, Aiman Suleiman, Sami Abu-Halaweh, Abeer Santarisi, Omar Shatnawi, Lara Shdaifat, Amjed Tarifi, Mohammad Al-Tamimi, Abdel-Ellah Al-Shudifat, Heba Alsmadi, Ahmed Al Sharqawi, Hadeel Alnawaiseh, Yara Anasweh, Farah Abo Domaidah, Haneen Abu Jaber, Mohammad Rashid Al-Zarir, Isam Bsisu
Summary: Fully vaccinated recipients of the Pfizer-BioNTech COVID-19 vaccine showed superior quantitative efficiency in specific antibody titers compared to those who received the Sinopharm vaccine. A booster dose is recommended for Sinopharm vaccine recipients or individuals with chronic immunosuppressive diseases.
Article
Urology & Nephrology
Seiji Kobayashi, Kazunori Fugo, Kazuto Yamazaki, Hiroyuki Terawaki
Summary: This case report describes the onset of minimal change disease (MCD) in a patient after receiving the second dose of the Pfizer-BioNTech mRNA vaccine for COVID-19. The patient achieved complete remission after treatment. While the definite causality between the vaccine and MCD is unclear, awareness of potential adverse effects of mRNA vaccines is crucial for determining their true incidence and frequency.
CLINICAL KIDNEY JOURNAL
(2021)
Article
Multidisciplinary Sciences
Mohammad Altermanini, Mhd Baraa Habib, Dania Alkhiyami, Khaled Ali, Mohamed Salah Abdelghani, Tahseen Hamamyh, Ahmad Elyas, Mawahib Elhassan
Summary: The Brugada syndrome is a rare inherited condition that increases the risk of ventricular tachyarrhythmias and sudden cardiac death. Fever, among other triggers, can cause the characteristic Brugada pattern on electrocardiogram. We report a case of syncope occurring two days after the administration of the BNT162b2 vaccine, attributed to fever-related unmasking of Brugada syndrome.
Article
Pediatrics
Mayme Marshall, Ian D. Ferguson, Paul Lewis, Preeti Jaggi, Christina Gagliardo, James Stewart Collins, Robin Shaughnessy, Rachel Caron, Cristina Fuss, Kathleen Jo E. Corbin, Leonard Emuren, Erin Faherty, E. Kevin Hall, Cecilia Di Pentima, Matthew E. Oster, Elijah Paintsil, Saira Siddiqui, Donna M. Timchak, Judith A. Guzman-Cottrill
Summary: This report presents 7 cases of acute myocarditis or myopericarditis in healthy male adolescents following the second dose of Pfizer-BioNTech COVID-19 vaccination, with patients rapidly recovering their symptoms through treatment with nonsteroidal anti-inflammatory drugs, intravenous immunoglobulin, and corticosteroids. The potential association between vaccine administration and myocarditis requires further monitoring and investigation.
Article
Immunology
Xuhua Xia
Summary: The design of Pfizer/BioNTech and Moderna mRNA vaccines involves various optimizations such as enhancing translation efficiency and improving mRNA stability. Different optimizations may conflict with each other, requiring compromises to be made.
Article
Immunology
Lisa Mueller, Marcel Andree, Wiebke Moskorz, Ingo Drexler, Lara Walotka, Ramona Grothmann, Johannes Ptok, Jonas Hillebrandt, Anastasia Ritchie, Denise Rabl, Philipp Niklas Ostermann, Rebekka Robitzsch, Sandra Hauka, Andreas Walker, Christopher Menne, Ralf Grutza, Jorg Timm, Ortwin Adams, Heiner Schaal
Summary: The study compared antibody responses to the BNT162b2 COVID-19 vaccine in young vaccinees below 60 and elderly vaccinees over 80. The elderly group had lower antibody titers and a lower frequency of neutralizing antibodies post-vaccination, indicating a potential need for closer monitoring or different vaccination strategies for this population.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Allergy
Emilia Anis, Sharon Alroy Preis, Noa Cedar, Yuval Tal, Isca Hershkowitz, Alon Y. Hershko
Summary: A study conducted in Israel investigated allergic reactions to COVID-19 vaccines and found that reporting of allergies decreased over time and did not affect vaccine adherence. A history of allergies may affect reporting profiles but not the occurrence of vaccine allergy.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2022)
Article
Multidisciplinary Sciences
Nazmul Islam, Natalie E. Sheils, Megan S. Jarvis, Kenneth Cohen
Summary: In this retrospective cohort study, Islam et al. found that mRNA-1273 vaccine provides slightly more protection against SARS-CoV-2 infection at 90 days compared to BNT162b2, but there are no significant differences in vaccine effectiveness for protection against hospitalization, ICU admission, or death/hospice transfer.
NATURE COMMUNICATIONS
(2022)
Article
Urology & Nephrology
Shota Obata, Sumi Hidaka, Mizuki Yamano, Mitsuru Yanai, Kunihiro Ishioka, Shuzo Kobayashi
Summary: COVID-19 vaccines may increase the risk of immune-mediated diseases, as shown in a case of ANCA-associated vasculitis following vaccination with the BNT162b2 vaccine. The causal relationship between the vaccine and vasculitis is uncertain, but environmental and genetic factors may have played a role in the development of the disease, with the vaccine potentially triggering a chain reaction.
CLINICAL KIDNEY JOURNAL
(2022)
