Proto-oncogene tyrosine-protein kinase SRC (Src) inhibition in microglia relieves neuroinflammation in neuropathic pain mouse models

Src Inhibition Attenuates Neuroinflammation and Protects Dopaminergic Neurons in Parkinson’s Disease Models

(2020) Hanyu Yang et al.   Frontiers in Neuroscience

Nuclear Functions of the Tyrosine Kinase Src

(2020) Giulia Bagnato et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IL-8 and MCP-1/CCL2 regulate proteolytic activity in triple negative inflammatory breast cancer a mechanism that might be modulated by Src and Erk1/2

(2020) Hossam Taha Mohamed et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

LRP1 deficiency in microglia blocks neuro-inflammation in the spinal dorsal horn and neuropathic pain processing

(2019) Coralie Brifault et al.   GLIA

Src family kinases, HCK and FGR, associate with local inflammation and tumour progression in colorectal cancer

(2019) Antonia K. Roseweir et al.   CELLULAR SIGNALLING

Targeting the complexity of Src signalling in the tumour microenvironment of pancreatic cancer: from mechanism to therapy

(2019) Ashleigh Parkin et al.   FEBS Journal

Microglia-neuron interactions in the models of neuropathic pain

(2019) Hidetoshi Tozaki-Saitoh et al.   BIOCHEMICAL PHARMACOLOGY

Flavonoid fisetin alleviates kidney inflammation and apoptosis via inhibiting Src-mediated NF-κB p65 and MAPK signaling pathways in septic AKI mice

(2019) Qian Ren et al.   BIOMEDICINE & PHARMACOTHERAPY

Mechanisms for Reducing Neuropathic Pain

(2019) Damien P. Kuffler   MOLECULAR NEUROBIOLOGY

Loganin prevents chronic constriction injury-provoked neuropathic pain by reducing TNF-α/IL-1β-mediated NF-κB activation and Schwann cell demyelination

(2019) Li-Wen Chu et al.   PHYTOMEDICINE

Inhibition of protein tyrosine phosphatase 1B in spinal cord dorsal horn of rats attenuated diabetic neuropathic pain

(2018) Ji-Yuan Zhao et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Andrographolide Antagonizes TNF-α-Induced IL-8 via Inhibition of NADPH Oxidase/ROS/NF-κB and Src/MAPKs/AP-1 Axis in Human Colorectal Cancer HCT116 Cells

(2018) Miaomiao Yuan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The Src module: an ancient scaffold in the evolution of cytoplasmic tyrosine kinases

(2018) Neel H. Shah et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

The receptor tyrosine kinase-like orphan receptor ROR2 modulates neuropathic pain via phosphorylation of N-methyl-D-aspartate receptor subunit GluN2B

(2018) X.L. Zhou et al.   BRITISH JOURNAL OF ANAESTHESIA

Matairesinol Suppresses Neuroinflammation and Migration Associated with Src and ERK1/2-NF-κB Pathway in Activating BV2 Microglia

(2017) Peng Xu et al.   NEUROCHEMICAL RESEARCH

Src family kinases (SFKs) and cell polarity in the testis

(2017) Xiang Xiao et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Effects of Src-kinase inhibition in cancer-induced bone pain

(2016) Milena De Felice et al.   Molecular Pain

Spinal Microgliosis Due to Resident Microglial Proliferation Is Required for Pain Hypersensitivity after Peripheral Nerve Injury

(2016) Nan Gu et al.   Cell Reports

Tumor necrosis factor-alpha is a potential diagnostic biomarker for chronic neuropathic pain after spinal cord injury

(2015) Jun Xu et al.   NEUROSCIENCE LETTERS

Wnt/Ryk signaling contributes to neuropathic pain by regulating sensory neuron excitability and spinal synaptic plasticity in rats

(2015) Su Liu et al.   PAIN

c-Src function is necessary and sufficient for triggering microglial cell activation

(2014) Renato Socodato et al.   GLIA

Surgical animal models of neuropathic pain: Pros and Cons

(2014) Siva Reddy Challa   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Immune responses of microglia in the spinal cord: Contribution to pain states

(2011) Dominic Schomberg et al.   EXPERIMENTAL NEUROLOGY

Amyloid-β oligomers stimulate microglia through a tyrosine kinase dependent mechanism

(2011) Gunjan Dhawan et al.   NEUROBIOLOGY OF AGING

Neuron–glia crosstalk gets serious: role in pain hypersensitivity

(2008) Ke Ren et al.   Current Opinion in Anesthesiology