PCSK9 regulates the NODAL signaling pathway and cellular proliferation in hiPSCs

In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates

(2021) Kiran Musunuru et al.   NATURE

Lipid-Modifying Agents, From Statins to PCSK9 Inhibitors

(2020) David Preiss et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

New Pharmacological Approaches to Target PCSK9

(2020) Alberico L. Catapano et al.   Current Atherosclerosis Reports

PANTHER version 16: a revised family classification, tree-based classification tool, enhancer regions and extensive API

(2020) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

Inhibiting PCSK9 — biology beyond LDL control

(2018) Robert M. Stoekenbroek et al.   Nature Reviews Endocrinology

Temporal and spatial requirements for Nodal-induced anterior mesendoderm and mesoderm in anterior neurulation

(2016) Ngawang Gonsar et al.   GENESIS

Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes

(2016) Brian A. Ference et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tumor-Induced Hyperlipidemia Contributes to Tumor Growth

(2016) Jianfeng Huang et al.   Cell Reports

Role of PCSK9 beyond liver involvement

(2015) Bertrand Cariou et al.   CURRENT OPINION IN LIPIDOLOGY

Activin/Nodal signalling in stem cells

(2015) S. Pauklin et al.   DEVELOPMENT

Identification of PCSK9 as a novel serum biomarker for the prenatal diagnosis of neural tube defects using iTRAQ quantitative proteomics

(2015) Dong An et al.   Scientific Reports

Proprotein Convertase Subtilisin/Kexin Type 9 Deficiency Reduces Melanoma Metastasis in Liver

(2015) Xiaowei Sun et al.   NEOPLASIA

Reviewing and Updating the Major Molecular Markers for Stem Cells

(2013) Raquel Calloni et al.   STEM CELLS AND DEVELOPMENT

TGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairs

(2011) Tao Huang et al.   EMBO JOURNAL

Genetic engineering of human pluripotent cells using TALE nucleases

(2011) Dirk Hockemeyer et al.   NATURE BIOTECHNOLOGY

Generation of human induced pluripotent stem cells by simple transient transfection of plasmid DNA encoding reprogramming factors

(2010) Karim Si-Tayeb et al.   BMC DEVELOPMENTAL BIOLOGY

SIP1 Mediates Cell-Fate Decisions between Neuroectoderm and Mesendoderm in Human Pluripotent Stem Cells

(2010) Zhenzhi Chng et al.   Cell Stem Cell

PCSK9 Dominant Negative Mutant Results in Increased LDL Catabolic Rate and Familial Hypobetalipoproteinemia

(2009) Bertrand Cariou et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Activin/Nodal signalling maintains pluripotency by controlling Nanog expression

(2009) L. Vallier et al.   DEVELOPMENT

Dissection of the Endogenous Cellular Pathways of PCSK9-induced Low Density Lipoprotein Receptor Degradation

(2009) Steve Poirier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PRDM14 suppresses expression of differentiation marker genes in human embryonic stem cells

(2008) Norihiro Tsuneyoshi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS