期刊
NANOMATERIALS
卷 12, 期 2, 页码 -出版社
MDPI
DOI: 10.3390/nano12020192
关键词
bacterial cellulose; composites; production; properties
类别
资金
- Ministry of Science and Higher Education of the Russian Federation [FSRZ-2020-0006]
This study investigated the synthesis of bacterial cellulose (BC) by Komagataeibacter xylinus strain B-12068 on various C-substrates under different culture conditions. The highest productivity of BC synthesis was achieved in static surface cultures, where large BC films were grown. Molasses and glycerol were found to be the most productive substrates. In addition, BC composites showed significant antibacterial activity against Escherichia coli and Staphylococcus aureus.
The synthesis of bacterial cellulose (BC) by Komagataeibacter xylinus strain B-12068 was investigated on various C-substrates, under submerged conditions with stirring and in static surface cultures. We implemented the synthesis of BC on glycerol, glucose, beet molasses, sprat oil, and a mixture of glucose with sunflower oil. The most productive process was obtained during the production of inoculum in submerged culture and subsequent growth of large BC films (up to 0.2 m(2) and more) in a static surface culture. The highest productivity of the BC synthesis process was obtained with the growth of bacteria on molasses and glycerol, 1.20 and 1.45 g/L per day, respectively. We obtained BC composites with silver nanoparticles (BC/AgNPs) and antibacterial drugs (chlorhexidine, baneocin, cefotaxime, and doripenem), and investigated the structure, physicochemical, and mechanical properties of composites. The disc-diffusion method showed pronounced antibacterial activity of BC composites against E. coli ATCC 25922 and S. aureus ATCC 25923.
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