Targeting Wnt Signaling in the Tumor Immune Microenvironment to Enhancing EpCAM CAR T-Cell therapy
出版年份 2021 全文链接
标题
Targeting Wnt Signaling in the Tumor Immune Microenvironment to Enhancing EpCAM CAR T-Cell therapy
作者
关键词
-
出版物
Frontiers in Pharmacology
Volume 12, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2021-11-01
DOI
10.3389/fphar.2021.724306
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A four-chemokine signature is associated with a T cell-inflamed phenotype in primary and metastatic pancreatic cancer
- (2020) Joan Miguel Romero et al. CLINICAL CANCER RESEARCH
- WNT/β-catenin pathway activation correlates with immune exclusion across human cancers
- (2019) Jason J. Luke et al. CLINICAL CANCER RESEARCH
- Optimization of manufacturing conditions for chimeric antigen receptor T cells to favor cells with a central memory phenotype
- (2019) TESSA Gargett et al. CYTOTHERAPY
- Pharmacological inhibition of β-catenin/BCL9 interaction overcomes resistance to immune checkpoint blockades by modulating Treg cells
- (2019) M. Feng et al. Science Advances
- Hypoxia modulates stem cell properties and induces EMT through N ‐glycosylation of EpCAM in breast cancer cells
- (2019) Dandan Zhang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Current challenges and emerging opportunities of CAR-T cell therapies
- (2019) Teresa R. Abreu et al. JOURNAL OF CONTROLLED RELEASE
- Extracellular domain of EpCAM enhances tumor progression through EGFR signaling in colon cancer cells
- (2018) Kang-Hao Liang et al. CANCER LETTERS
- Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia
- (2018) Joseph A. Fraietta et al. NATURE MEDICINE
- Genetic Mechanisms of Immune Evasion in Colorectal Cancer
- (2018) Catherine S. Grasso et al. Cancer Discovery
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- RNAi-Mediated β-Catenin Inhibition Promotes T Cell Infiltration and Antitumor Activity in Combination with Immune Checkpoint Blockade
- (2018) Shanthi Ganesh et al. MOLECULAR THERAPY
- TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells
- (2018) Sanjeev Mariathasan et al. NATURE
- Chimeric antigen receptor T-cell therapy — assessment and management of toxicities
- (2017) Sattva S. Neelapu et al. Nature Reviews Clinical Oncology
- Tumor-Specific T Cell Dysfunction Is a Dynamic Antigen-Driven Differentiation Program Initiated Early during Tumorigenesis
- (2016) Andrea Schietinger et al. IMMUNITY
- Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies
- (2016) Marco Ruella et al. JOURNAL OF CLINICAL INVESTIGATION
- Randomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma
- (2016) Stephanie L. Goff et al. JOURNAL OF CLINICAL ONCOLOGY
- Reprogramming the tumor microenvironment to enhance adoptive cellular therapy
- (2016) Paul A. Beavis et al. SEMINARS IN IMMUNOLOGY
- TRUCKs: the fourth generation of CARs
- (2015) Markus Chmielewski et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
- (2015) Stefani Spranger et al. NATURE
- Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy
- (2015) E. Sotillo et al. Cancer Discovery
- Differentiation of CD8 memory T cells depends on Foxo1
- (2013) Rodrigo Hess Michelini et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Differential Localization of T-bet and Eomes in CD8 T Cell Memory Populations
- (2013) L. M. McLane et al. JOURNAL OF IMMUNOLOGY
- Id2-Mediated Inhibition of E2A Represses Memory CD8+ T Cell Differentiation
- (2013) F. Masson et al. JOURNAL OF IMMUNOLOGY
- Tumor microenvironment and lymphocyte infiltration
- (2012) Gwendoline Rahir et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Epithelial cell adhesion molecule expression (CD326) in cancer: A short review
- (2011) Carlo Patriarca et al. CANCER TREATMENT REVIEWS
- Chimeric antigen receptor (CAR)-engineered lymphocytes for cancer therapy
- (2011) Carlos A Ramos et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Trafficking of CAR-Engineered Human T Cells Following Regional or Systemic Adoptive Transfer in SCID Beige Mice
- (2011) Ana Caterina Parente-Pereira et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Cutting Edge: -Catenin Is Dispensable for T Cell Effector Differentiation, Memory Formation, and Recall Responses
- (2011) M. Prlic et al. JOURNAL OF IMMUNOLOGY
- A critical role for TCF-1 in T-lineage specification and differentiation
- (2011) Brittany Nicole Weber et al. NATURE
- Blimp-1 Transcription Factor Is Required for the Differentiation of Effector CD8+ T Cells and Memory Responses
- (2009) Axel Kallies et al. IMMUNITY
- Chimeric Antigen Receptors Combining 4-1BB and CD28 Signaling Domains Augment PI3kinase/AKT/Bcl-XL Activation and CD8+ T Cell–mediated Tumor Eradication
- (2009) Xiao-Song Zhong et al. MOLECULAR THERAPY
- Prognostic Effect of Epithelial Cell Adhesion Molecule Overexpression in Untreated Node-Negative Breast Cancer
- (2008) M. Schmidt et al. CLINICAL CANCER RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation