Neuropeptides and Behaviors: How Small Peptides Regulate Nervous System Function and Behavioral Outputs

Increased dopaminergic neurotransmission results in ethanol dependent sedative behaviors in Caenorhabditis elegans

(2021) Pratima Pandey et al.   PLoS Genetics

Mitochondrial hydrogen peroxide positively regulates neuropeptide secretion during diet-induced activation of the oxidative stress response

(2021) Qi Jia et al.   Nature Communications

Investigating autism associated genes in C. elegans reveals candidates with a role in social behaviour

(2021) Helena Rawsthorne et al.   PLoS One

Neuropeptide S Displays as a Key Neuromodulator in Olfactory Spatial Memory

(2020) Can Wang et al.   CHEMICAL SENSES

Neuromedin U signaling regulates retrieval of learned salt avoidance in a C. elegans gustatory circuit

(2020) Jan Watteyne et al.   Nature Communications

Olfactory specificity regulates lipid metabolism through neuroendocrine signaling in Caenorhabditis elegans

(2020) Ayse Sena Mutlu et al.   Nature Communications

Neuroendocrine control of lipid metabolism: lessons from C. elegans

(2020) Supriya Srinivasan   JOURNAL OF NEUROGENETICS

NPY/NPF-Related Neuropeptide FLP-34 Signals from Serotonergic Neurons to Modulate Aversive Olfactory Learning in Caenorhabditis elegans

(2020) Melissa Fadda et al.   JOURNAL OF NEUROSCIENCE

Evolution of Orexin Neuropeptide System: Structure and Function

(2020) Shingo Soya et al.   Frontiers in Neuroscience

Insulin: too much of a good thing is bad

(2020) Hubert Kolb et al.   BMC Medicine

Myoinhibitory peptide signaling modulates aversive gustatory learning in Caenorhabditis elegans

(2019) Katleen Peymen et al.   PLoS Genetics

Parallel Multimodal Circuits Control an Innate Foraging Behavior

(2019) Alejandro López-Cruz et al.   NEURON

Cannabinoids stimulate the TRP-channel dependent release of both serotonin and dopamine to modulate behavior in C. elegans

(2019) Mitchell Oakes et al.   JOURNAL OF NEUROSCIENCE

Sexually dimorphic regulation of behavioral states by dopamine in Caenorhabditis elegans

(2019) Satoshi Suo et al.   JOURNAL OF NEUROSCIENCE

Neuropeptide S Ameliorates Cognitive Impairment of APP/PS1 Transgenic Mice by Promoting Synaptic Plasticity and Reducing Aβ Deposition

(2019) Peng Zhao et al.   Frontiers in Behavioral Neuroscience

Differential Regulation of Innate and Learned Behavior by Creb1/Crh-1 in Caenorhabditis elegans

(2019) Yogesh Dahiya et al.   JOURNAL OF NEUROSCIENCE

Control of Locomotory Behavior of Caenorhabditis elegans by the Immunoglobulin Superfamily Protein RIG-3

(2019) Ashwani Bhardwaj et al.   GENETICS

A GABAergic and peptidergic sleep neuron as a locomotion stop neuron with compartmentalized Ca2+ dynamics

(2019) Wagner Steuer Costa et al.   Nature Communications

Pheromones Modulate Learning by Regulating the Balanced Signals of Two Insulin-like Peptides

(2019) Taihong Wu et al.   NEURON

FLP-18 Functions through the G-Protein-Coupled Receptors NPR-1 and NPR-4 to Modulate Reversal Length inCaenorhabditis elegans

(2018) Ashwani Bhardwaj et al.   JOURNAL OF NEUROSCIENCE

FLP-1 neuropeptides modulate sensory and motor circuits in the nematode Caenorhabditis elegans

(2018) Ingrid Buntschuh et al.   PLoS One

Rictor/TORC2 mediates gut-to-brain signaling in the regulation of phenotypic plasticity in C. elegans

(2018) Michael P. O’Donnell et al.   PLoS Genetics

PDF-1 neuropeptide signaling regulates sexually dimorphic gene expression in shared sensory neurons of C. elegans

(2018) Zoë A Hilbert et al.   eLife

A Caenorhabditis elegans assay of seizure-like activity optimised for identifying antiepileptic drugs and their mechanisms of action

(2018) Shi Quan Wong et al.   JOURNAL OF NEUROSCIENCE METHODS

An Afferent Neuropeptide System Transmits Mechanosensory Signals Triggering Sensitization and Arousal in C. elegans

(2018) Yee Lian Chew et al.   NEURON

Neuropeptides encoded by nlp-49 modulate locomotion, arousal and egg-laying behaviours in Caenorhabditis elegans via the receptor SEB-3

(2018) Yee Lian Chew et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Food Sensation Modulates Locomotion by Dopamine and Neuropeptide Signaling in a Distributed Neuronal Network

(2018) Alexandra Oranth et al.   NEURON

Overview of Neuropeptides: Awakening the Senses?

(2017) Andrew F. Russo   HEADACHE

Genetic variation in glia–neuron signalling modulates ageing rate

(2017) Jiang-An Yin et al.   NATURE

A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism

(2017) Lavinia Palamiuc et al.   Nature Communications

An Intestine-Derived Neuropeptide Controls Avoidance Behavior in Caenorhabditis elegans

(2017) Kiho Lee et al.   Cell Reports

Genetic and neuronal regulation of sleep by neuropeptide VF

(2017) Daniel A Lee et al.   eLife

The neuropeptide F/nitric oxide pathway is essential for shaping locomotor plasticity underlying locust phase transition

(2017) Li Hou et al.   eLife

Luqin-like RYamide peptides regulate food-evoked responses in C. elegans

(2017) Hayao Ohno et al.   eLife

C. elegans Stress-Induced Sleep Emerges from the Collective Action of Multiple Neuropeptides

(2016) Ravi D. Nath et al.   CURRENT BIOLOGY

Enkephalin and dynorphin neuropeptides are differently correlated with locomotor hypersensitivity and levodopa-induced dyskinesia in parkinsonian rats

(2016) Stefania Sgroi et al.   EXPERIMENTAL NEUROLOGY

Multiple excitatory and inhibitory neural signals converge to fine-tune Caenorhabditis elegans feeding to food availability

(2016) Nicolas Dallière et al.   FASEB JOURNAL

The Neuropeptides FLP-2 and PDF-1 Act in Concert To Arouse Caenorhabditis elegans Locomotion

(2016) D. Chen et al.   GENETICS

Context-dependent regulation of feeding behaviour by the insulin receptor, DAF-2, in Caenorhabditis elegans

(2016) James Dillon et al.   INVERTEBRATE NEUROSCIENCE

Alcohol Regulates BK Surface Expression via Wnt/ -Catenin Signaling

(2016) C. Velazquez-Marrero et al.   JOURNAL OF NEUROSCIENCE

Neural Architecture of Hunger-Dependent Multisensory Decision Making in C. elegans

(2016) D. Dipon Ghosh et al.   NEURON

FLP-4 neuropeptide and its receptor in a neuronal circuit regulate preference choice through functions of ASH-2 trithorax complex in Caenorhabditis elegans

(2016) Yonglin Yu et al.   Scientific Reports

Caenorhabditis elegans Male Copulation Circuitry Incorporates Sex-Shared Defecation Components To Promote Intromission and Sperm Transfer

(2016) Brigitte LeBoeuf et al.   G3-Genes Genomes Genetics

Neuropeptide-Driven Cross-Modal Plasticity following Sensory Loss in Caenorhabditis elegans

(2016) Ithai Rabinowitch et al.   PLOS BIOLOGY

NPR-9, a Galanin-Like G-Protein Coupled Receptor, and GLR-1 Regulate Interneuronal Circuitry Underlying Multisensory Integration of Environmental Cues in Caenorhabditis elegans

(2016) Jason C. Campbell et al.   PLoS Genetics

Neuroendocrine modulation sustains the C. elegans forward motor state

(2016) Maria A Lim et al.   eLife

Sleep-active neuron specification and sleep induction require FLP-11 neuropeptides to systemically induce sleep

(2016) Michal Turek et al.   eLife

Kynurenic Acid Is a Nutritional Cue that Enables Behavioral Plasticity

(2015) George A. Lemieux et al.   CELL

Oxytocin enables maternal behaviour by balancing cortical inhibition

(2015) Bianca J. Marlin et al.   NATURE

NPY signaling inhibits extended amygdala CRF neurons to suppress binge alcohol drinking

(2015) Kristen E Pleil et al.   NATURE NEUROSCIENCE

Neuropeptide S Increases locomotion activity through corticotropin-releasing factor receptor 1 in substantia nigra of mice

(2015) M.S. Li et al.   PEPTIDES

An opioid-like system regulating feeding behavior in C. elegans

(2015) Mi Cheong Cheong et al.   eLife

Modulation of Locomotion and Reproduction by FLP Neuropeptides in the Nematode Caenorhabditis elegans

(2015) Yan-Jung Chang et al.   PLoS One

FRPR-4 Is a G-Protein Coupled Neuropeptide Receptor That Regulates Behavioral Quiescence and Posture in Caenorhabditis elegans

(2015) Matthew D. Nelson et al.   PLoS One

Neurobiology of Caenorhabditis elegans Locomotion: Where Do We Stand?

(2014) Julijana Gjorgjieva et al.   BIOSCIENCE

Cellular Stress Induces a Protective Sleep-like State in C. elegans

(2014) Andrew J. Hill et al.   CURRENT BIOLOGY

FMRFamide-like FLP-13 Neuropeptides Promote Quiescence following Heat Stress in Caenorhabditis elegans

(2014) Matthew D. Nelson et al.   CURRENT BIOLOGY

Nematode Tango Milonguero – The C. elegans male's search for the hermaphrodite vulva

(2014) Amrita L. Sherlekar et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Chemical mating cues in C. elegans

(2014) Christopher D. Chute et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Exploratory decisions of the Caenorhabditis elegans male: A conflict of two drives

(2014) Arantza Barrios   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A Conserved Dopamine-Cholecystokinin Signaling Pathway Shapes Context–Dependent Caenorhabditis elegans Behavior

(2014) Raja Bhattacharya et al.   PLoS Genetics

Caenorhabditis elegans male sensory-motor neurons and dopaminergic support cells couple ejaculation and post-ejaculatory behaviors

(2014) Brigitte LeBoeuf et al.   eLife

Serotonin and the Neuropeptide PDF Initiate and Extend Opposing Behavioral States in C. elegans

(2013) Steven W. Flavell et al.   CELL

The FMRFamide-related neuropeptide FLP-20 is required in the mechanosensory neurons during memory for massed training in C. elegans

(2013) C. Li et al.   LEARNING & MEMORY

Analysis of NPR-1 Reveals a Circuit Mechanism for Behavioral Quiescence in C. elegans

(2013) Seungwon Choi et al.   NEURON

Two Insulin-like Peptides Antagonistically Regulate Aversive Olfactory Learning in C. elegans

(2013) Zhunan Chen et al.   NEURON

The C. elegans Male Exercises Directional Control during Mating through Cholinergic Regulation of Sex-Shared Command Interneurons

(2013) Amrita L. Sherlekar et al.   PLoS One

Insulin/IGF-1 Signaling, including Class II/III PI3Ks, β-Arrestin and SGK-1, Is Required in C. elegans to Maintain Pharyngeal Muscle Performance during Starvation

(2013) Donard S. Dwyer et al.   PLoS One

The Roles of Neuropeptides in Caenorhabditis elegans Including their Importance in the Regulation of Feeding and Metabolism

(2013) Lindy Holden-Dye et al.   PROTEIN AND PEPTIDE LETTERS

The neuropeptide NLP-22 regulates a sleep-like state in Caenorhabditis elegans

(2013) M.D. Nelson et al.   Nature Communications

Neuropeptides Function in a Homeostatic Manner to Modulate Excitation-Inhibition Imbalance in C. elegans

(2013) Tamara M. Stawicki et al.   PLoS Genetics

The Role of NPY and Ghrelin in Anorexia Nervosa

(2012) Lei Zhang et al.   CURRENT PHARMACEUTICAL DESIGN

SEB-3, a CRF receptor-like GPCR, regulates locomotor activity states, stress responses and ethanol tolerance inCaenorhabditiselegans

(2012) C. Jee et al.   GENES BRAIN AND BEHAVIOR

PDF-1 neuropeptide signaling modulates a neural circuit for mate-searching behavior in C. elegans

(2012) Arantza Barrios et al.   NATURE NEUROSCIENCE

Stress-Related Neuropeptides and Addictive Behaviors: Beyond the Usual Suspects

(2012) Jesse R. Schank et al.   NEURON

Neuropeptide Transmission in Brain Circuits

(2012) Anthony N. van den Pol   NEURON

A Predictable Worm: Application of Caenorhabditis elegans for Mechanistic Investigation of Movement Disorders

(2012) Paige M. Dexter et al.   Neurotherapeutics

Oxytocin/Vasopressin-Related Peptides Have an Ancient Role in Reproductive Behavior

(2012) J. L. Garrison et al.   SCIENCE

C. elegans Dopaminergic D2-Like Receptors Delimit Recurrent Cholinergic-Mediated Motor Programs during a Goal-Oriented Behavior

(2012) Paola Correa et al.   PLoS Genetics

The Neural Circuits and Synaptic Mechanisms Underlying Motor Initiation in C. elegans

(2011) Beverly J. Piggott et al.   CELL

Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor

(2011) Kerry J. Ressler et al.   NATURE

A Neuropeptide-Mediated Stretch Response Links Muscle Contraction to Changes in Neurotransmitter Release

(2011) Zhitao Hu et al.   NEURON

A Hormone-Activated Central Pattern Generator for Courtship

(2010) Daniel A. Wagenaar et al.   CURRENT BIOLOGY

Neuropeptides in the Drosophila central complex in modulation of locomotor behavior

(2010) L. Kahsai et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Neuropeptide feedback modifies odor-evoked dynamics in Caenorhabditis elegans olfactory neurons

(2010) Sreekanth H Chalasani et al.   NATURE NEUROSCIENCE

Differential Association of Circadian Genes with Mood Disorders: CRY1 and NPAS2 are Associated with Unipolar Major Depression and CLOCK and VIP with Bipolar Disorder

(2010) Virginia Soria et al.   NEUROPSYCHOPHARMACOLOGY

Central control of penile erection: A re-visitation of the role of oxytocin and its interaction with dopamine and glutamic acid in male rats

(2010) Maria Rosaria Melis et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Phenotypic plasticity in development and evolution: facts and concepts

(2010) G. Fusco et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A Differential Role for Neuropeptides in Acute and Chronic Adaptive Responses to Alcohol: Behavioural and Genetic Analysis in Caenorhabditis elegans

(2010) Philippa Mitchell et al.   PLoS One

Metabolic Stress Responses in Drosophila Are Modulated by Brain Neurosecretory Cells That Produce Multiple Neuropeptides

(2010) Lily Kahsai et al.   PLoS One

Ventral lateral and DN1 clock neurons mediate distinct properties of male sex drive rhythm in Drosophila

(2010) S. Fujii et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coordinated Regulation of Foraging and Metabolism in C. elegans by RFamide Neuropeptide Signaling

(2009) Merav Cohen et al.   Cell Metabolism

Discovery and characterization of a conserved pigment dispersing factor-like neuropeptide pathway inCaenorhabditis elegans

(2009) Tom Janssen et al.   JOURNAL OF NEUROCHEMISTRY

Molecular Mechanisms of Sleep and Wakefulness

(2008) Miroslaw Mackiewicz et al.   Annals of the New York Academy of Sciences

Discovery of a Cholecystokinin-Gastrin-Like Signaling System in Nematodes

(2008) Tom Janssen et al.   ENDOCRINOLOGY

Activity-dependent volume transmission by transgene NPY attenuates glutamate release and LTP in the subiculum

(2008) Andreas T. Sørensen et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Lethargus is a Caenorhabditis elegans sleep-like state

(2008) David M. Raizen et al.   NATURE

A Role for Brain Stress Systems in Addiction

(2008) George F. Koob   NEURON

A Caenorhabditis elegans allatostatin/galanin-like receptor NPR-9 inhibits local search behavior in response to feeding cues

(2008) W. G. Bendena et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA