Surface functionalisation-dependent adverse effects of metal nanoparticles and nanoplastics in zebrafish embryos

Towards FAIR nanosafety data

(2021) Nina Jeliazkova et al.   Nature Nanotechnology

Differential Nanoparticle Sequestration by Macrophages and Scavenger Endothelial Cells Visualized in Vivo in Real-Time and at Ultrastructural Resolution

(2020) Yuya Hayashi et al.   ACS Nano

Surface Chemistry-Dependent Evolution of the Nanomaterial Corona on TiO2 Nanomaterials Following Uptake and Sub-Cellular Localization

(2020) Abdullah O. Khan et al.   Nanomaterials

Multigenerational Exposures of Daphnia Magna to Pristine and Aged Silver Nanoparticles: Epigenetic Changes and Phenotypical Ageing Related Effects

(2020) Laura‐Jayne A. Ellis et al.   Small

Barrier function of zebrafish embryonic chorions against microplastics and nanoplastics and its impact on embryo development

(2020) Zhenghua Duan et al.   JOURNAL OF HAZARDOUS MATERIALS

Zebrafish: An emerging model to study microplastic and nanoplastic toxicity

(2020) Jacky Bhagat et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Development of Deep Learning Models for Predicting the Effects of Exposure to Engineered Nanomaterials on Daphnia magna

(2020) Pantelis Karatzas et al.   Small

Pax6 organizes the anterior eye segment by guiding two distinct neural crest waves

(2020) Masanari Takamiya et al.   PLoS Genetics

Nearly free surface silanols are the critical molecular moieties that initiate the toxicity of silica particles

(2020) Cristina Pavan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Size matters: Zebrafish (Danio rerio) as a model to study toxicity of nanoplastics from cells to the whole organism

(2020) M. Sendra et al.   ENVIRONMENTAL POLLUTION

Gathering at the top? Environmental controls of microplastic uptake and biomagnification in freshwater food webs

(2020) Stefan Krause et al.   ENVIRONMENTAL POLLUTION

Emergence of nanoplastic in the environment and possible impact on human health

(2019) Roman Lehner et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Biocompatibility of Amine‐Functionalized Silica Nanoparticles: The Role of Surface Coverage

(2019) I‐Lun Hsiao et al.   Small

Synthesis of metal-doped nanoplastics and their utility to investigate fate and behaviour in complex environmental systems

(2019) Denise M. Mitrano et al.   Nature Nanotechnology

A high throughput imaging database of toxicological effects of nanomaterials tested on HepaRG cells

(2019) Elisabeth Joossens et al.   Scientific Data

Zebrafish: Housing and husbandry recommendations

(2019) Peter Aleström et al.   LABORATORY ANIMALS

The puzzling issue of silica toxicity: are silanols bridging the gaps between surface states and pathogenicity?

(2019) Cristina Pavan et al.   Particle and Fibre Toxicology

Uptake, tissue distribution, and toxicity of polystyrene nanoparticles in developing zebrafish ( Danio rerio )

(2018) Jordan A. Pitt et al.   AQUATIC TOXICOLOGY

Cationic polystyrene nanoparticle and the sea urchin immune system: biocorona formation, cell toxicity, and multixenobiotic resistance phenotype

(2018) L. F. Marques-Santos et al.   Nanotoxicology

Fate of Nanoplastics in Marine Larvae: A Case Study Using Barnacles, Amphibalanus amphitrite

(2018) Samarth Bhargava et al.   ACS Sustainable Chemistry & Engineering

Intrinsically Fluorescent, Stealth Polypyrazoline Nanoparticles with Large Stokes Shift for In Vivo Imaging

(2018) Shivshankar R. Mane et al.   Small

Quantifying ecological risks of aquatic micro- and nanoplastic

(2018) Ellen Besseling et al.   CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY

Effects of polymethylmethacrylate nanoplastics on Dicentrarchus labrax

(2018) I. Brandts et al.   GENOMICS

Automated morphological feature assessment for zebrafish embryo developmental toxicity screens

(2018) Elisabet Teixidó et al.   TOXICOLOGICAL SCIENCES

Relevance of nano- and microplastics for freshwater ecosystems: A critical review

(2018) Rita Triebskorn et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Amino-modified polystyrene nanoparticles affect signalling pathways of the sea urchin (Paracentrotus lividus) embryos

(2017) Annalisa Pinsino et al.   Nanotoxicology

Enhanced uptake of BPA in the presence of nanoplastics can lead to neurotoxic effects in adult zebrafish

(2017) Qiqing Chen et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Autophagy induced by silica nanoparticles protects RAW264.7 macrophages from cell death

(2017) Clarissa Marquardt et al.   TOXICOLOGY

Modeling of Interactions between the Zebrafish Hatching Enzyme ZHE1 and A Series of Metal Oxide Nanoparticles: Nano-QSAR and Causal Analysis of Inactivation Mechanisms

(2017) Natalia Sizochenko et al.   Nanomaterials

Validation of weak biological effects by round robin experiments: cytotoxicity/biocompatibility of SiO2 and polymer nanoparticles in HepG2 cells

(2017) Lisa Landgraf et al.   Scientific Reports

Brain damage and behavioural disorders in fish induced by plastic nanoparticles delivered through the food chain

(2017) Karin Mattsson et al.   Scientific Reports

Highly Flexible Platform for Tuning Surface Properties of Silica Nanoparticles and Monitoring Their Biological Interaction

(2016) Isaac Ojea-Jiménez et al.   ACS Applied Materials & Interfaces

A critical evaluation of the fish early-life stage toxicity test for engineered nanomaterials: experimental modifications and recommendations

(2016) Benjamin J. Shaw et al.   ARCHIVES OF TOXICOLOGY

Biomimetic nanomaterials: Development of protein coated nanoceria as a potential antioxidative nano-agent for the effective scavenging of reactive oxygen species in vitro and in zebrafish model

(2016) Bharat Bhushan et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Sensory systems and ionocytes are targets for silver nanoparticle effects in fish

(2016) Olivia J. Osborne et al.   Nanotoxicology

Uptake and toxicity of methylmethacrylate-based nanoplastic particles in aquatic organisms

(2015) Andy M. Booth et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

The hazard assessment of nanostructured CeO2-based mixed oxides on the zebrafish Danio rerio under environmentally relevant UV-A exposure

(2015) Anita Jemec et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Aspect Ratio Plays a Role in the Hazard Potential of CeO2 Nanoparticles in Mouse Lung and Zebrafish Gastrointestinal Tract

(2014) Sijie Lin et al.   ACS Nano

Effects of metal nanoparticles on the lateral line system and behaviour in early life stages of zebrafish (Danio rerio)

(2014) Paul L. McNeil et al.   AQUATIC TOXICOLOGY

Systematic Investigation of the Physicochemical Factors That Contribute to the Toxicity of ZnO Nanoparticles

(2014) Qingshan Mu et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Accumulation and Embryotoxicity of Polystyrene Nanoparticles at Early Stage of Development of Sea Urchin Embryos Paracentrotus lividus

(2014) C. Della Torre et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Altered Behavior, Physiology, and Metabolism in Fish Exposed to Polystyrene Nanoparticles

(2014) Karin Mattsson et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

High Content Analysis Provides Mechanistic Insights on the Pathways of Toxicity Induced by Amine-Modified Polystyrene Nanoparticles

(2014) Sergio Anguissola et al.   PLoS One

Comparative effects of zinc oxide nanoparticles and dissolved zinc on zebrafish embryos and eleuthero-embryos: Importance of zinc ions

(2014) Nadja Rebecca Brun et al.   SCIENCE OF THE TOTAL ENVIRONMENT

DMSO modifies the permeability of the zebrafish (Danio rerio) chorion-Implications for the fish embryo test (FET)

(2013) B. Kais et al.   AQUATIC TOXICOLOGY

Acute ZnO nanoparticles exposure induces developmental toxicity, oxidative stress and DNA damage in embryo-larval zebrafish

(2013) Xuesong Zhao et al.   AQUATIC TOXICOLOGY

Cardiovascular toxicity evaluation of silica nanoparticles in endothelial cells and zebrafish model

(2013) Junchao Duan et al.   BIOMATERIALS

Assessment of nanosilver toxicity during zebrafish (Danio rerio) development

(2013) Andrey Massarsky et al.   CHEMOSPHERE

Producing nanotubes of biocompatible hydroxyapatite by continuous hydrothermal synthesis

(2013) Edward Lester et al.   CRYSTENGCOMM

TiO2 Nanoparticle Exposure and Illumination during Zebrafish Development: Mortality at Parts per Billion Concentrations

(2013) Ofek Bar-Ilan et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Influence of Humic Acid on Titanium Dioxide Nanoparticle Toxicity to Developing Zebrafish

(2013) Sarah P. Yang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Microplastic Ingestion by Zooplankton

(2013) Matthew Cole et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Zinc ions as effectors of environmental oxidative lung injury

(2013) Weidong Wu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Silver nanoparticles induce developmental stage-specific embryonic phenotypes in zebrafish

(2013) Kerry J. Lee et al.   Nanoscale

Mechanistic insights into the effect of nanoparticles on zebrafish hatch

(2013) Kimberly Jessica Ong et al.   Nanotoxicology

The zebrafish reference genome sequence and its relationship to the human genome

(2013) Kerstin Howe et al.   NATURE

Toxic Effects of Silica Nanoparticles on Zebrafish Embryos and Larvae

(2013) Junchao Duan et al.   PLoS One

Oxidative stress effects of titanium dioxide nanoparticle aggregates in zebrafish embryos

(2013) Melissa Faria et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Automated Processing of Zebrafish Imaging Data: A Survey

(2013) Ralf Mikut et al.   Zebrafish

Effect of Lighting Conditions on Zebrafish Growth and Development

(2013) Natalia Villamizar et al.   Zebrafish

Mechanisms of Silver Nanoparticle Release, Transformation and Toxicity: A Critical Review of Current Knowledge and Recommendations for Future Studies and Applications

(2013) Bogumiła Reidy et al.   Materials

A Chemical Screening System for Glucocorticoid Stress Hormone Signaling in an Intact Vertebrate

(2012) Benjamin D. Weger et al.   ACS Chemical Biology

Surface Defects on Plate-Shaped Silver Nanoparticles Contribute to Its Hazard Potential in a Fish Gill Cell Line and Zebrafish Embryos

(2012) Saji George et al.   ACS Nano

In Vivo Quantitative Study of Sized-Dependent Transport and Toxicity of Single Silver Nanoparticles Using Zebrafish Embryos

(2012) Kerry J. Lee et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Effects of four CeO2 nanocrystalline catalysts on early-life stages of zebrafish Danio rerio and crustacean Daphnia magna

(2012) Anita Jemec et al.   JOURNAL OF HAZARDOUS MATERIALS

Effects of particle size and coating on nanoscale Ag and TiO2exposure in zebrafish (Danio rerio) embryos

(2012) Olivia J. Osborne et al.   Nanotoxicology

Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism

(2012) Philipp Gut et al.   Nature Chemical Biology

Automated Phenotype Recognition for Zebrafish Embryo Based In Vivo High Throughput Toxicity Screening of Engineered Nano-Materials

(2012) Rong Liu et al.   PLoS One

Zebrafish High-Throughput Screening to Study the Impact of Dissolvable Metal Oxide Nanoparticles on the Hatching Enzyme, ZHE1

(2012) Sijie Lin et al.   Small

Zebrafish: An In Vivo Model for Nano EHS Studies

(2012) Sijie Lin et al.   Small

Use of a High-Throughput Screening Approach Coupled with In Vivo Zebrafish Embryo Screening To Develop Hazard Ranking for Engineered Nanomaterials

(2011) Saji George et al.   ACS Nano

Physiological effects of nanoparticles on fish: A comparison of nanometals versus metal ions

(2011) Benjamin J. Shaw et al.   ENVIRONMENT INTERNATIONAL

Titanium dioxide nanoparticles produce phototoxicity in the developing zebrafish

(2011) Ofek Bar-Ilan et al.   Nanotoxicology

Silver nanoparticles alter zebrafish development and larval behavior: Distinct roles for particle size, coating and composition

(2011) Christina M. Powers et al.   NEUROTOXICOLOGY AND TERATOLOGY

Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes

(2011) Wan-Seob Cho et al.   Particle and Fibre Toxicology

Zebrafish embryos as an alternative to animal experiments—A commentary on the definition of the onset of protected life stages in animal welfare regulations

(2011) Uwe Strähle et al.   REPRODUCTIVE TOXICOLOGY

Effects of nano-scale TiO2, ZnO and their bulk counterparts on zebrafish: Acute toxicity, oxidative stress and oxidative damage

(2011) Daowen Xiong et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Assessment of uptake and toxicity of fluorescent silica nanoparticles in zebrafish (Danio rerio) early life stages

(2010) Karl Fent et al.   AQUATIC TOXICOLOGY

A review of the in vivo and in vitro toxicity of silver and gold particulates: Particle attributes and biological mechanisms responsible for the observed toxicity

(2010) Helinor J. Johnston et al.   CRITICAL REVIEWS IN TOXICOLOGY

Silver nanoparticles: Behaviour and effects in the aquatic environment

(2010) Julia Fabrega et al.   ENVIRONMENT INTERNATIONAL

High-throughput in vivo vertebrate screening

(2010) Carlos Pardo-Martin et al.   NATURE METHODS

Fate and Effects of CeO2Nanoparticles in Aquatic Ecotoxicity Tests

(2009) Karen Van Hoecke et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Modeled Environmental Concentrations of Engineered Nanomaterials (TiO2, ZnO, Ag, CNT, Fullerenes) for Different Regions

(2009) Fadri Gottschalk et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Automated high-throughput mapping of promoter-enhancer interactions in zebrafish embryos

(2009) Jochen Gehrig et al.   NATURE METHODS

Zebrafish embryos as models for embryotoxic and teratological effects of chemicals

(2009) Lixin Yang et al.   REPRODUCTIVE TOXICOLOGY

Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties

(2008) Tian Xia et al.   ACS Nano

The ecotoxicology and chemistry of manufactured nanoparticles

(2008) Richard D. Handy et al.   ECOTOXICOLOGY

Manufactured nanoparticles: their uptake and effects on fish—a mechanistic analysis

(2008) Richard D. Handy et al.   ECOTOXICOLOGY