The proteomic architecture of schizophrenia iPSC-derived cerebral organoids reveals alterations in GWAS and neuronal development factors
出版年份 2021 全文链接
标题
The proteomic architecture of schizophrenia iPSC-derived cerebral organoids reveals alterations in GWAS and neuronal development factors
作者
关键词
-
出版物
Translational Psychiatry
Volume 11, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-10-20
DOI
10.1038/s41398-021-01664-5
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Multiple Neurodevelopmental Mechanisms of Schizophrenia in Patient-Derived Cerebral Organoids
- (2021) Michael Notaras et al. BIOLOGICAL PSYCHIATRY
- Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
- (2021) Annalisa L.E. Carli et al. PROTEOMICS
- Carboxypeptidase E Regulates Activity-Dependent TrkB Neuronal Surface Insertion and Hippocampal Memory
- (2021) Na Li et al. JOURNAL OF NEUROSCIENCE
- Neurodevelopmental signatures of narcotic and neuropsychiatric risk factors in 3D human-derived forebrain organoids
- (2021) Michael Notaras et al. MOLECULAR PSYCHIATRY
- Patient-derived iPSC-cerebral organoid modeling of the 17q11.2 microdeletion syndrome establishes CRLF3 as a critical regulator of neurogenesis
- (2021) Michelle L. Wegscheid et al. Cell Reports
- Cerebral organoid and mouse models reveal a RAB39b–PI3K–mTOR pathway-dependent dysregulation of cortical development leading to macrocephaly/autism phenotypes
- (2020) Wei Zhang et al. GENES & DEVELOPMENT
- Sustained subcutaneous delivery of secretome of human cardiac stem cells promotes cardiac repair following myocardial infarction
- (2020) Andrew R Kompa et al. CARDIOVASCULAR RESEARCH
- Transcriptomic Landscape and Functional Characterization of Induced Pluripotent Stem Cell–Derived Cerebral Organoids in Schizophrenia
- (2020) Annie Kathuria et al. JAMA Psychiatry
- Developmental excitation-inhibition imbalance underlying psychoses revealed by single-cell analyses of discordant twins-derived cerebral organoids
- (2020) Tomoyo Sawada et al. MOLECULAR PSYCHIATRY
- PsychENCODE and beyond: transcriptomics and epigenomics of brain development and organoids
- (2020) Alexandre Jourdon et al. NEUROPSYCHOPHARMACOLOGY
- Neuronal defects in a human cellular model of 22q11.2 deletion syndrome
- (2020) Themasap A. Khan et al. NATURE MEDICINE
- Positive association between PTN polymorphisms and schizophrenia in Northeast Chinese Han population
- (2020) Ye Lv et al. PSYCHIATRIC GENETICS
- Immune Factor, TNFα, Disrupts Human Brain Organoid Development Similar to Schizophrenia—Schizophrenia Increases Developmental Vulnerability to TNFα
- (2020) Courtney A. Benson et al. Frontiers in Cellular Neuroscience
- Effect of Cell Spreading on Rosette Formation by Human Pluripotent Stem Cell-Derived Neural Progenitor Cells
- (2020) Ryan F. Townshend et al. Frontiers in Cell and Developmental Biology
- Modeling brain development and diseases with human cerebral organoids
- (2020) Yingchao Shi et al. CURRENT OPINION IN NEUROBIOLOGY
- Cell type-specific gene expression patterns associated with posttraumatic stress disorder in World Trade Center responders
- (2019) Pei-Fen Kuan et al. Translational Psychiatry
- Neurocalcin Delta Knockout Impairs Adult Neurogenesis Whereas Half Reduction Is Not Pathological
- (2019) Aaradhita Upadhyay et al. Frontiers in Molecular Neuroscience
- Altered neuronal migratory trajectories in human cerebral organoids derived from individuals with neuronal heterotopia
- (2019) Johannes Klaus et al. NATURE MEDICINE
- Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution
- (2019) Alex A. Pollen et al. CELL
- iPSC-derived homogeneous populations of developing schizophrenia cortical interneurons have compromised mitochondrial function
- (2019) Peiyan Ni et al. MOLECULAR PSYCHIATRY
- The maternal immune activation model uncovers a role for the Arx gene in GABAergic dysfunction in schizophrenia
- (2019) Jay P. Nakamura et al. BRAIN BEHAVIOR AND IMMUNITY
- Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss
- (2019) Angeliki M. Nikolakopoulou et al. NATURE NEUROSCIENCE
- Distinct Vulnerability and Resilience of Human Neuroprogenitor Subtypes in Cerebral Organoid Model of Prenatal Hypoxic Injury
- (2019) Nicolas Daviaud et al. Frontiers in Cellular Neuroscience
- Long-Lasting Rescue of Network and Cognitive Dysfunction in a Genetic Schizophrenia Model
- (2019) Arghya Mukherjee et al. CELL
- Synaptic deficits in iPSC-derived cortical interneurons in schizophrenia are mediated by NLGN2 and rescued by N-acetylcysteine
- (2019) Annie Kathuria et al. Translational Psychiatry
- Chronic methamphetamine interacts with BDNF Val66Met to remodel psychosis pathways in the mesocorticolimbic proteome
- (2019) David W. Greening et al. MOLECULAR PSYCHIATRY
- Psychiatry in a Dish: Stem Cells and Brain Organoids Modeling Autism Spectrum Disorders
- (2018) Mirolyba Ilieva et al. BIOLOGICAL PSYCHIATRY
- OUP accepted manuscript
- (2018) CEREBRAL CORTEX
- The daunting polygenicity of mental illness: making a new map
- (2018) Steven E. Hyman PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Polymorphism in Tmem132d regulates expression and anxiety-related behavior through binding of RNA polymerase II complex
- (2018) Roshan R. Naik et al. Translational Psychiatry
- Common and Rare Genetic Risk Factors Converge in Protein Interaction Networks Underlying Schizophrenia
- (2018) Xiao Chang et al. Frontiers in Genetics
- Neural Stem Cells Behave as a Functional Niche for the Maturation of Newborn Neurons through the Secretion of PTN
- (2018) Changyong Tang et al. NEURON
- Brain-Derived Neurotrophic Factor (BDNF): Novel Insights into Regulation and Genetic Variation
- (2018) Michael Notaras et al. NEUROSCIENTIST
- The PRIDE database and related tools and resources in 2019: improving support for quantification data
- (2018) Yasset Perez-Riverol et al. NUCLEIC ACIDS RESEARCH
- Cellular Retinoic Acid–Binding Protein 1 Modulates Stem Cell Proliferation to Affect Learning and Memory in Male Mice
- (2017) Yu-Lung Lin et al. ENDOCRINOLOGY
- DISC1 Regulates Neurogenesis via Modulating Kinetochore Attachment of Ndel1/Nde1 during Mitosis
- (2017) Fei Ye et al. NEURON
- A Novel Single Nucleotide T980C Polymorphism in the Human Carboxypeptidase E Gene Results in Loss of Neuroprotective Function
- (2017) Lin Cong et al. PLoS One
- Quantitative Map of Proteome Dynamics during Neuronal Differentiation
- (2017) Christian K. Frese et al. Cell Reports
- Cerebral organoids reveal early cortical maldevelopment in schizophrenia—computational anatomy and genomics, role of FGFR1
- (2017) E. K. Stachowiak et al. Translational Psychiatry
- Zika Virus Depletes Neural Progenitors in Human Cerebral Organoids through Activation of the Innate Immune Receptor TLR3
- (2016) Jason Dang et al. Cell Stem Cell
- Modeling synaptogenesis in schizophrenia and autism using human iPSC derived neurons
- (2016) Christa W. Habela et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- The Perseus computational platform for comprehensive analysis of (prote)omics data
- (2016) Stefka Tyanova et al. NATURE METHODS
- Building brains in a dish: Prospects for growing cerebral organoids from stem cells
- (2016) John O. Mason et al. NEUROSCIENCE
- Zika virus impairs growth in human neurospheres and brain organoids
- (2016) P. P. Garcez et al. SCIENCE
- Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain
- (2016) Chongyuan Luo et al. Cell Reports
- FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders
- (2015) Jessica Mariani et al. CELL
- Human cerebral organoids recapitulate gene expression programs of fetal neocortex development
- (2015) J. Gray Camp et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia
- (2014) K Brennand et al. MOLECULAR PSYCHIATRY
- Generation of cerebral organoids from human pluripotent stem cells
- (2014) Madeline A Lancaster et al. Nature Protocols
- Mirror neuron dysfunction in schizophrenia and its functional implications: A systematic review
- (2014) Urvakhsh Meherwan Mehta et al. SCHIZOPHRENIA RESEARCH
- Carboxypeptidase E (NF-α1): a new trophic factor in neuroprotection
- (2014) Yong Cheng et al. Neuroscience Bulletin
- Human iPSC Neurons Display Activity-Dependent Neurotransmitter Secretion: Aberrant Catecholamine Levels in Schizophrenia Neurons
- (2014) Vivian Hook et al. Stem Cell Reports
- Inhibitory neurons in human cortical circuits: substrate for cognitive dysfunction in schizophrenia
- (2013) David A Lewis CURRENT OPINION IN NEUROBIOLOGY
- Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients
- (2013) O Robicsek et al. MOLECULAR PSYCHIATRY
- Cerebral organoids model human brain development and microcephaly
- (2013) Madeline A. Lancaster et al. NATURE
- Potential biomarkers in psychiatry: focus on the cholesterol system
- (2012) Alisa G. Woods et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Cortical basket cell dysfunction in schizophrenia
- (2012) Allison A. Curley et al. JOURNAL OF PHYSIOLOGY-LONDON
- Metabolomic Profiling to Identify Potential Serum Biomarkers for Schizophrenia and Risperidone Action
- (2011) Jiekun Xuan et al. JOURNAL OF PROTEOME RESEARCH
- GABA Neuron Alterations, Cortical Circuit Dysfunction and Cognitive Deficits in Schizophrenia
- (2011) Guillermo Gonzalez-Burgos et al. NEURAL PLASTICITY
- Podocalyxin Is a Novel Polysialylated Neural Adhesion Protein with Multiple Roles in Neural Development and Synapse Formation
- (2010) Nathalia Vitureira et al. PLoS One
- Different apolipoprotein E, apolipoprotein A1 and prostaglandin-H2 D-isomerase levels in cerebrospinal fluid of schizophrenia patients and healthy controls
- (2010) Daniel Martins-De-Souza et al. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
- MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
- (2008) Jürgen Cox et al. NATURE BIOTECHNOLOGY
- GABA Neurons and the Mechanisms of Network Oscillations: Implications for Understanding Cortical Dysfunction in Schizophrenia
- (2008) G. Gonzalez-Burgos et al. SCHIZOPHRENIA BULLETIN
- Plasma apolipoprotein E is decreased in schizophrenia spectrum and bipolar disorder
- (2007) Brian Dean et al. PSYCHIATRY RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started