Filarial Lymphedema Patients Are Characterized by Exhausted CD4+ T Cells

Financial burden impact quality of life among lymphatic Filariasis patients

(2021) Samuel Opoku Asiedu et al.   BMC PUBLIC HEALTH

Distinct Immune Profiles of Exhausted Effector and Memory CD8+ T Cells in Individuals With Filarial Lymphedema

(2021) Sacha Horn et al.   Frontiers in Cellular and Infection Microbiology

The clinical characteristics of lower extremity lymphedema in 440 patients

(2020) Steven M. Dean et al.   Journal of Vascular Surgery-Venous and Lymphatic Disorders

The impact of leprosy, podoconiosis and lymphatic filariasis on family quality of life: A qualitative study in Northwest Ethiopia

(2020) Anna T. van ‘t Noordende et al.   PLoS Neglected Tropical Diseases

Wuchereria bancrofti-infected individuals harbor distinct IL-10-producing regulatory B and T cell subsets which are affected by anti-filarial treatment

(2019) Manuel Ritter et al.   PLoS Neglected Tropical Diseases

CD4+ T cell exhaustion revealed by high PD-1 and LAG-3 expression and the loss of helper T cell function in chronic hepatitis B

(2019) Yuejiao Dong et al.   BMC IMMUNOLOGY

Wuchereria bancrofti infection is linked to systemic activation of CD4 and CD8 T cells

(2019) Inge Kroidl et al.   PLoS Neglected Tropical Diseases

Helminth-induced Th2 cell dysfunction is distinct from exhaustion and is maintained in the absence of antigen

(2019) Johanna A. Knipper et al.   PLoS Neglected Tropical Diseases

Seroepidemiology of helminths and the association with severe malaria among infants and young children in Tanzania

(2018) Jennifer L. Kwan et al.   PLoS Neglected Tropical Diseases

Myeloid cell recruitment versus local proliferation differentiates susceptibility from resistance to filarial infection

(2018) Sharon M Campbell et al.   eLife

T-cell tolerance and exhaustion in the clearance of Echinococcus multilocularis: role of inoculum size in a quantitative hepatic experimental model

(2017) Chuanshan Zhang et al.   Scientific Reports

The Chronic Stages of Bovine Fasciola hepatica Are Dominated by CD4 T-Cell Exhaustion

(2017) Divya Sachdev et al.   Frontiers in Immunology

Fasciola hepaticategumental antigens induce anergic-like T cells via dendritic cells in a mannose receptor-dependent manner

(2016) Allison Aldridge et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Effect of Wuchereria bancrofti infection on HIV incidence in southwest Tanzania: a prospective cohort study

(2016) Inge Kroidl et al.   LANCET

Reductions in microfilaridermia by repeated ivermectin treatment are associated with lower Plasmodium-specific Th17 immune responses in Onchocerca volvulus-infected individuals

(2015) Kathrin Arndts et al.   Parasites & Vectors

CD39 Expression Identifies Terminally Exhausted CD8+ T Cells

(2015) Prakash K. Gupta et al.   PLoS Pathogens

Incidence of Active Pulmonary Tuberculosis in Patients with Coincident Filarial and/or Intestinal Helminth Infections Followed Longitudinally in South India

(2014) Soumya Chatterjee et al.   PLoS One

Progress and Impact of 13 Years of the Global Programme to Eliminate Lymphatic Filariasis on Reducing the Burden of Filarial Disease

(2014) K. D. Ramaiah et al.   PLoS Neglected Tropical Diseases

Helminth Infections Coincident with Active Pulmonary Tuberculosis Inhibit Mono- and Multifunctional CD4+ and CD8+ T Cell Responses in a Process Dependent on IL-10

(2014) Parakkal Jovvian George et al.   PLoS Pathogens

Immunology of lymphatic filariasis

(2013) S. Babu et al.   PARASITE IMMUNOLOGY

Th2 Cell-Intrinsic Hypo-Responsiveness Determines Susceptibility to Helminth Infection

(2013) Nienke van der Werf et al.   PLoS Pathogens

Immunopathogenesis of lymphatic filarial disease

(2012) Subash Babu et al.   Seminars in Immunopathology

Elevated Adaptive Immune Responses Are Associated with Latent Infections of Wuchereria bancrofti

(2012) Kathrin Arndts et al.   PLoS Neglected Tropical Diseases

Regulatory T Cells in Human Lymphatic Filariasis: Stronger Functional Activity in Microfilaremics

(2012) Linda J. Wammes et al.   PLoS Neglected Tropical Diseases

T cell exhaustion

(2011) E John Wherry   NATURE IMMUNOLOGY

Elevated Levels of Plasma Angiogenic Factors Are Associated with Human Lymphatic Filarial Infections

(2010) Sasisekhar Bennuru et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Induction of immunoglobulin G4 in human filariasis: an indicator of immunoregulation

(2010) T. Adjobimey et al.   ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY

At Homeostasis Filarial Infections Have Expanded Adaptive T Regulatory but Not Classical Th2 Cells

(2010) S. Metenou et al.   JOURNAL OF IMMUNOLOGY

Th2 cell hyporesponsiveness during chronic murine schistosomiasis is cell intrinsic and linked to GRAIL expression

(2009) Justin J. Taylor et al.   JOURNAL OF CLINICAL INVESTIGATION

Filarial Lymphedema Is Characterized by Antigen-Specific Th1 and Th17 Proinflammatory Responses and a Lack of Regulatory T Cells

(2009) Subash Babu et al.   PLoS Neglected Tropical Diseases

Lymphangiogenesis and Lymphatic Remodeling Induced by Filarial Parasites: Implications for Pathogenesis

(2009) Sasisekhar Bennuru et al.   PLoS Pathogens