Wnt signaling mediates acquisition of blood–brain barrier properties in naïve endothelium derived from human pluripotent stem cells
出版年份 2021 全文链接
标题
Wnt signaling mediates acquisition of blood–brain barrier properties in naïve endothelium derived from human pluripotent stem cells
作者
关键词
-
出版物
eLife
Volume 10, Issue -, Pages -
出版商
eLife Sciences Publications, Ltd
发表日期
2021-11-10
DOI
10.7554/elife.70992
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate
- (2021) Tyler M. Lu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells
- (2021) Qiuyu Guo et al. eLife
- Integrative analysis of the human brain mural cell transcriptome
- (2021) Benjamin D Gastfriend et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Decoding the development of the human hippocampus
- (2020) Suijuan Zhong et al. NATURE
- Identification of a combination of transcription factors that synergistically increases endothelial cell barrier resistance
- (2020) Filip Roudnicky et al. Scientific Reports
- A genome-wide view of the de-differentiation of central nervous system endothelial cells in culture
- (2020) Mark F Sabbagh et al. eLife
- The blood–brain barrier in health and disease: Important unanswered questions
- (2020) Caterina P. Profaci et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Construction of a human cell landscape at single-cell level
- (2020) Xiaoping Han et al. NATURE
- Recent advances in human iPSC-derived models of the blood–brain barrier
- (2020) Michael J. Workman et al. Fluids and Barriers of the CNS
- Lack of Flvcr2 impairs brain angiogenesis without affecting the blood-brain barrier
- (2020) Nicolas Santander et al. JOURNAL OF CLINICAL INVESTIGATION
- Inducers of the endothelial cell barrier identified through chemogenomic screening in genome-edited hPSC-endothelial cells
- (2020) Filip Roudnicky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human CNS barrier-forming organoids with cerebrospinal fluid production
- (2020) Laura Pellegrini et al. SCIENCE
- Transcriptomic comparison of human and mouse brain microvessels
- (2020) Hannah W. Song et al. Scientific Reports
- Commentary on human pluripotent stem cell-based blood–brain barrier models
- (2020) Ethan S. Lippmann et al. Fluids and Barriers of the CNS
- UniProt: the universal protein knowledgebase in 2021
- (2020) et al. NUCLEIC ACIDS RESEARCH
- Astrocyte-derived Wnt growth factors are required for endothelial blood-brain barrier maintenance
- (2020) Sylvaine Guérit et al. PROGRESS IN NEUROBIOLOGY
- Claudin-3-deficient C57BL/6J mice display intact brain barriers
- (2019) Mariana Castro Dias et al. Scientific Reports
- Human pluripotent stem cell–derived brain pericyte–like cells induce blood-brain barrier properties
- (2019) Matthew J. Stebbins et al. Science Advances
- Beta-catenin signaling regulates barrier-specific gene expression in circumventricular organ and ocular vasculatures
- (2019) Yanshu Wang et al. eLife
- Low wnt/β-catenin signaling determines leaky vessels in the subfornical organ and affects water homeostasis in mice
- (2019) Fabienne Benz et al. eLife
- Human iPSC-Derived Blood-Brain Barrier Chips Enable Disease Modeling and Personalized Medicine Applications
- (2019) Gad D. Vatine et al. Cell Stem Cell
- A Single-Cell Transcriptomic Atlas of Human Neocortical Development during Mid-gestation
- (2019) Damon Polioudakis et al. NEURON
- WNT/β-catenin modulates the axial identity of embryonic stem cell-derived human neural crest
- (2019) Gustavo A. Gomez et al. DEVELOPMENT
- Conserved cell types with divergent features in human versus mouse cortex
- (2019) Rebecca D. Hodge et al. NATURE
- Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood–brain barrier dysfunction module
- (2019) Roeben Nocon Munji et al. NATURE NEUROSCIENCE
- Ensembl 2020
- (2019) Andrew D Yates et al. NUCLEIC ACIDS RESEARCH
- Derivation of Brain Capillary-like Endothelial Cells from Human Pluripotent Stem Cell-Derived Endothelial Progenitor Cells
- (2019) Catarina Praça et al. Stem Cell Reports
- Modulation of Wnt/β-catenin signaling promotes blood-brain barrier phenotype in cultured brain endothelial cells
- (2019) Marlyn D. Laksitorini et al. Scientific Reports
- The Human Transcription Factors
- (2018) Samuel A. Lambert et al. CELL
- A molecular mechanism for Wnt ligand-specific signaling
- (2018) Marie Eubelen et al. SCIENCE
- A molecular atlas of cell types and zonation in the brain vasculature
- (2018) Michael Vanlandewijck et al. NATURE
- Barrier properties and transcriptome expression in human iPSC-derived models of the blood-brain barrier
- (2018) Louise Delsing et al. STEM CELLS
- Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells
- (2018) Mark F Sabbagh et al. eLife
- Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types
- (2018) Liqun He et al. Scientific Data
- Fine Tuning of Sox17 and Canonical Wnt Coordinates the Permeability Properties of the Blood-Brain Barrier
- (2018) Monica Corada et al. CIRCULATION RESEARCH
- Wnt/β-catenin signaling regulates VE-cadherin-mediated anastomosis of brain capillaries by counteracting S1pr1 signaling
- (2018) Kathleen Hübner et al. Nature Communications
- A RECK-WNT7 Receptor-Ligand Interaction Enables Isoform-Specific Regulation of Wnt Bioavailability
- (2018) Mario Vallon et al. Cell Reports
- Brain barriers in health and disease
- (2017) Richard Daneman et al. NEUROBIOLOGY OF DISEASE
- The Wnt Inhibitor Apcdd1 Coordinates Vascular Remodeling and Barrier Maturation of Retinal Blood Vessels
- (2017) Jenna Mazzoni et al. NEURON
- Reck and Gpr124 Are Essential Receptor Cofactors for Wnt7a/Wnt7b-Specific Signaling in Mammalian CNS Angiogenesis and Blood-Brain Barrier Regulation
- (2017) Chris Cho et al. NEURON
- Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis
- (2017) Benjamin J. Andreone et al. NEURON
- Huntington’s Disease iPSC-Derived Brain Microvascular Endothelial Cells Reveal WNT-Mediated Angiogenic and Blood-Brain Barrier Deficits
- (2017) Ryan G. Lim et al. Cell Reports
- Directed differentiation of human pluripotent stem cells to blood-brain barrier endothelial cells
- (2017) Tongcheng Qian et al. Science Advances
- Medulloblastoma Genotype Dictates Blood Brain Barrier Phenotype
- (2016) Timothy N. Phoenix et al. CANCER CELL
- Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells
- (2016) Gioele La Manno et al. CELL
- Differentiation and characterization of human pluripotent stem cell-derived brain microvascular endothelial cells
- (2016) Matthew J. Stebbins et al. METHODS
- Notch regulates BMP responsiveness and lateral branching in vessel networks via SMAD6
- (2016) Kevin P. Mouillesseaux et al. Nature Communications
- Endothelial β-Catenin Signaling Is Required for Maintaining Adult Blood–Brain Barrier Integrity and Central Nervous System HomeostasisCLINICAL PERSPECTIVE
- (2015) Khiem A. Tran et al. CIRCULATION
- LSR/angulin-1 is a tricellular tight junction protein involved in blood–brain barrier formation
- (2015) Fabien Sohet et al. JOURNAL OF CELL BIOLOGY
- Brain barriers: Crosstalk between complex tight junctions and adherens junctions
- (2015) Silvia Tietz et al. JOURNAL OF CELL BIOLOGY
- Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells
- (2015) Christoph Patsch et al. NATURE CELL BIOLOGY
- Glycogen synthase kinase-3 (GSK3): Regulation, actions, and diseases
- (2015) Eleonore Beurel et al. PHARMACOLOGY & THERAPEUTICS
- Generation of functional hippocampal neurons from self-organizing human embryonic stem cell-derived dorsomedial telencephalic tissue
- (2015) Hideya Sakaguchi et al. Nature Communications
- Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis
- (2015) Benoit Vanhollebeke et al. eLife
- The Molecular Signatures Database Hallmark Gene Set Collection
- (2015) Arthur Liberzon et al. Cell Systems
- Sox7, Sox17, and Sox18 Cooperatively Regulate Vascular Development in the Mouse Retina
- (2015) Yulian Zhou et al. PLoS One
- Novel insights into the development and maintenance of the blood–brain barrier
- (2014) Britta Engelhardt et al. CELL AND TISSUE RESEARCH
- Mfsd2a is critical for the formation and function of the blood–brain barrier
- (2014) Ayal Ben-Zvi et al. NATURE
- Instruction of Circulating Endothelial Progenitors In Vitro towards Specialized Blood-Brain Barrier and Arterial Phenotypes
- (2014) Julie Boyer-Di Ponio et al. PLoS One
- A Stable and Reproducible Human Blood-Brain Barrier Model Derived from Hematopoietic Stem Cells
- (2014) Romeo Cecchelli et al. PLoS One
- Efficient Differentiation of Human Pluripotent Stem Cells to Endothelial Progenitors via Small-Molecule Activation of WNT Signaling
- (2014) Xiaojun Lian et al. Stem Cell Reports
- Development, maintenance and disruption of the blood-brain barrier
- (2013) Birgit Obermeier et al. NATURE MEDICINE
- Wnt Activation of Immortalized Brain Endothelial Cells as a Tool for Generating a Standardized Model of the Blood Brain Barrier In Vitro
- (2013) Roberta Paolinelli et al. PLoS One
- Norrin/Frizzled4 Signaling in Retinal Vascular Development and Blood Brain Barrier Plasticity
- (2012) Yanshu Wang et al. CELL
- Lack of endothelial diaphragms in fenestrae and caveolae of mutant Plvap-deficient mice
- (2012) Leonie Herrnberger et al. HISTOCHEMISTRY AND CELL BIOLOGY
- Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells
- (2012) Ethan S Lippmann et al. NATURE BIOTECHNOLOGY
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- Fast gapped-read alignment with Bowtie 2
- (2012) Ben Langmead et al. NATURE METHODS
- Cozzarelli Prize Winner: Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling
- (2012) X. Lian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural Basis of Wnt Recognition by Frizzled
- (2012) C. Y. Janda et al. SCIENCE
- Insulin Inhibits Cardiac Mesoderm, Not Mesendoderm, Formation During Cardiac Differentiation of Human Pluripotent Stem Cells and Modulation of Canonical Wnt Signaling Can Rescue This Inhibition
- (2012) Xiaojun Lian et al. STEM CELLS
- RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
- (2011) Bo Li et al. BMC BIOINFORMATICS
- Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors
- (2011) Yasuo Uchida et al. JOURNAL OF NEUROCHEMISTRY
- GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier
- (2011) M. Cullen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pericytes regulate the blood–brain barrier
- (2010) Annika Armulik et al. NATURE
- Pericytes are required for blood–brain barrier integrity during embryogenesis
- (2010) Richard Daneman et al. NATURE
- The Mouse Blood-Brain Barrier Transcriptome: A New Resource for Understanding the Development and Function of Brain Endothelial Cells
- (2010) Richard Daneman et al. PLoS One
- Essential Regulation of CNS Angiogenesis by the Orphan G Protein-Coupled Receptor GPR124
- (2010) F. Kuhnert et al. SCIENCE
- Norrin, Frizzled-4, and Lrp5 Signaling in Endothelial Cells Controls a Genetic Program for Retinal Vascularization
- (2009) Xin Ye et al. CELL
- Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt
- (2009) Steffen Durinck et al. Nature Protocols
- Wnt/ -catenin signaling is required for CNS, but not non-CNS, angiogenesis
- (2009) R. Daneman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- WGCNA: an R package for weighted correlation network analysis
- (2008) Peter Langfelder et al. BMC BIOINFORMATICS
- Species Differences in Blood-Brain Barrier Transport of Three Positron Emission Tomography Radioligands with Emphasis on P-Glycoprotein Transport
- (2008) S. Syvanen et al. DRUG METABOLISM AND DISPOSITION
- Wnt/β-catenin signaling controls development of the blood–brain barrier
- (2008) Stefan Liebner et al. JOURNAL OF CELL BIOLOGY
- R-Spondin Family Members Regulate the Wnt Pathway by a Common Mechanism
- (2008) Kyung-Ah Kim et al. MOLECULAR BIOLOGY OF THE CELL
- Canonical Wnt Signaling Regulates Organ-Specific Assembly and Differentiation of CNS Vasculature
- (2008) J. M. Stenman et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now