Review
Chemistry, Multidisciplinary
Zinovia Surlari, Dragos Ioan Virvescu, Elena-Raluca Baciu, Roxana-Ionela Vasluianu, Dana Gabriela Budala
Summary: Periodontal disease can have a systemic impact on the body, with potential links to other diseases like oral cancer. It is unclear if specific periodontal bacteria play a role in promoting systemic illness, but research suggests a correlation between periodontitis and oral cancer. Additional research is needed to strengthen this link and understand the mediators between these two pathologies.
APPLIED SCIENCES-BASEL
(2021)
Review
Microbiology
Roxana Loriana Negrut, Adrian Cote, Adrian Marius Maghiar
Summary: There is growing evidence that certain periodontopathogens, such as Fusobacterium nucleatum, in the oral microbiota may contribute to the development of colorectal cancer and could potentially be used as a biomarker for diagnosis.
Article
Dentistry, Oral Surgery & Medicine
An Li, Lianmin Chen, Renske Z. Thomas, Ubele van der Velden, Amaliya Amaliya, Luc W. M. van der Sluis, Annemarie A. Schuller, G-H E. Tjakkes
Summary: The study found strong correlations in periodontal characteristics between adjacent teeth, especially in severe periodontitis cases. Teeth adjacent to TLPD tooth were observed to have the most severe alveolar bone loss.
JOURNAL OF DENTISTRY
(2021)
Article
Microbiology
Natalia S. Rozas, Gena D. Tribble, Cameron B. Jeter
Summary: This study found significant differences in the oral microbiota of patients with PD compared to healthy controls, possibly due to factors such as dysphagia, drooling, and salivary pH. Understanding the factors influencing their oral microbiota could lead to the development of diagnostic and treatment strategies to improve the quality of life and survival of these patients.
Article
Oncology
Ji Zhang, Rino Bellocco, Gunilla Sandborgh-Englund, Jingru Yu, Margaret Sallberg Chen, Weimin Ye
Summary: This study found an association between poor dental health and increased risk of esophageal cancer, including both esophageal adenocarcinoma and esophageal squamous cell carcinoma. Root canal infection and periodontitis were associated with increased risk of esophageal adenocarcinoma, and fewer remaining teeth also increased the risk of both histopathological types of esophageal cancer.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2022)
Article
Health Care Sciences & Services
Georgios S. Chatzopoulos, Ziou Jiang, Nicholas Marka, Larry F. Wolff
Summary: The study aimed to analyze the relationship between the extent, severity, and rate of progression of periodontitis and systemic diseases as well as smoking. The analysis of a large database showed that smokers were significantly associated with rapid progression of periodontitis (grade C), while gender, age, number of missing teeth, and number of tooth loss during supportive periodontal treatment were associated with disease characteristics.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Anders Holmlund, Lars Lind
Summary: The study found that the number of teeth and baseline BOP were dose-dependently associated with incident diabetes. Poor response to treatment was associated with a 37% increased risk for future diabetes.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2021)
Article
Environmental Sciences
Najith Amarasena, Sergio Chrisopoulos, Lisa M. Jamieson, Liana Luzzi
Summary: Based on the findings of the National Study of Adult Oral Health in Australia, nearly one third of Australian adults had untreated dental caries, 29% had gingivitis, and 30.1% had periodontitis. Poorer oral health was evident in Australians from lower socioeconomic backgrounds, indicating socioeconomic inequalities in oral health. Time trends showed improvement in dental caries experience and tooth retention over 30 years, but deterioration in periodontal health between 2004-06 and 2017-18.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Shaima Al-Harthi, Giovanni Barbagallo, Alessandro Psaila, Umberto d'Urso, Luigi Nibali
Summary: This study highlights the importance of oral hygiene habits, initial bone loss, caries, and endodontic disease in predicting tooth survival in a primary care setting. Patients who did not receive professional mechanical plaque removal had a slightly higher rate of tooth loss compared to those who did.
JOURNAL OF PERIODONTOLOGY
(2022)
Article
Oncology
Baijun Zhou, Jiayun Lu, James D. Beck, Kevin L. Moss, Anna E. Prizment, Ryan T. Demmer, Kori A. Porosnicu Rodriguez, Corinne E. Joshu, Dominique S. Michaud, Elizabeth A. Platz
Summary: This study explores the associations between periodontal bacteria and lung cancer risk. The results indicate positive associations between certain oral bacteria, particularly the orange complex, and lung cancer, suggesting a potential role of periodontal bacteria in lung cancer etiology. Further research is needed to validate these associations and develop novel lung cancer prevention strategies.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2023)
Article
Multidisciplinary Sciences
Takamasa Komiyama, Takashi Ohi, Wakana Ito, Yoshitada Miyoshi, Takako Hiratsuka, Sanae Matsuyama, Ichiro Tsuji, Makoto Watanabe, Yoshinori Hattori
Summary: This prospective cohort study examined the relationship between the number of remaining teeth, maximum occlusal force, and incidence of gastrointestinal cancer in community-dwelling older Japanese individuals. The study found that low maximum occlusal force was associated with the incidence of gastrointestinal cancer.
SCIENTIFIC REPORTS
(2022)
Review
Biochemistry & Molecular Biology
Mattia Di Stefano, Alessandro Polizzi, Simona Santonocito, Alessandra Romano, Teresa Lombardi, Gaetano Isola
Summary: The oral cavity harbors a complex microbial community, which can lead to periodontal damage. Periodontal disease is a common chronic inflammatory condition globally, with diverse clinical manifestations.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biology
Ana Duran-Pinedo, Jose Solbiati, Flavia Teles, Ricardo Teles, Yanping Zang, Jorge Frias-Lopez
Summary: The study found that stable sites in periodontitis progression were characterized by high asynchrony, directional changes dominating community reordering, and new species more likely to be recruited if a close relative was not recruited previously. Progressing sites exhibited low asynchrony and convergence, while fluctuating sites had high asynchrony, community convergence, and a neutral recruitment model.
Article
Multidisciplinary Sciences
Giang T. Vu, Shaminul Shakib, Christian King, Varadraj Gurupur, Bert B. Little
Summary: This study examined the association between uncontrolled diabetes and periodontal disease (PD) among adults in the United States. The findings showed that uncontrolled diabetes was significantly associated with a higher risk of PD. Factors such as annual dental visits, female gender, and college education were found to decrease the prevalence of PD, while smoking, non-white race, low income, and older age increased the risk of PD.
SCIENTIFIC REPORTS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Muhammad H. A. Saleh, Debora R. Dias, Obada Mandil, Ricardo P. de Oliveira, Abdusalam Alrmali, Mauricio G. Araujo, Hom-Lay Wang, Zoltan Barath, Istvan A. Urban
Summary: Patients with RPc >= 5 mm at more than 15% of the sites are at risk for tooth loss. Grading and RPc >= 5 mm displayed very good predictive capability of TLP.
JOURNAL OF PERIODONTOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Jinli Li, Fatemeh Momen-Heravi, Xun Wu, Kaili He
Summary: This study reveals the involvement of METTL14 in the regulation of cell proliferation in oral squamous cell carcinoma (OSCC) through the MALAT1/miR-224-5p/KDM2A axis.
Letter
Dermatology
Fadwa Ahmed, Isabelle Moseley, Erica Lin, Rachel Lim, Navya Baranwal, Megan Hoang, Tiffany Libby, Oliver Wisco, Leslie Robinson-Bostom, Sameer Gupta, Abrar Qureshi, Eunyoung Cho
JOURNAL OF INVESTIGATIVE DERMATOLOGY
(2023)
Article
Oncology
Hanna Elomaa, Maarit Ahtiainen, Sara A. Vaeyrynen, Shuji Ogino, Jonathan A. Nowak, Mai Chan Lau, Olli Helminen, Erkki-Ville Wirta, Toni T. Seppaelae, Jan Boehm, Jukka-Pekka Mecklin, Teijo Kuopio, Juha P. Vaeyrynen
Summary: The expression patterns and prognostic significance of PD-L1 and PD-1 in the colorectal cancer microenvironment are inadequately characterised. This study found that PD-L1(+) macrophages and PD-1(+) T cells were associated with better clinical outcomes in colorectal cancer patients. These findings enhance the understanding of immune checkpoints in the tumor microenvironment and could contribute to the development of improved immunotherapies.
BRITISH JOURNAL OF CANCER
(2023)
Article
Oncology
Zhangyan Lyu, Dong Hang, Xiaosheng He, Kana Wu, Yin Cao, Bernard Rosner, Andrew T. Chan, Shuji Ogino, Ni Li, Min Dai, Edward L. Giovannucci, Mingyang Song
Summary: A simple prediction model based on five major risk factors for high-risk serrated polyps (SPs) was developed and validated, which may be useful for providing healthy lifestyle recommendations and tailored colorectal cancer screening.
CANCER PREVENTION RESEARCH
(2023)
Letter
Dermatology
Erica M. Lin, Abrar A. Qureshi, Oliver Wisco, Eunyoung Cho
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2023)
Letter
Dermatology
Megan M. Tran, Isabelle H. Moseley, Elisabeth A. George, Abrar A. Qureshi, Eunyoung Cho
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2023)
Article
Oncology
Irmina Maria Michalek, Rebecca E. Graff, Alejandro Sanchez, Toni K. Choueiri, Eunyoung Cho, Mark A. Preston, Kathryn M. Wilson
Summary: Through analyzing data from several large-scale studies, it is found that the use of statins is not significantly associated with the risk of renal cell carcinoma (RCC). However, in women, it may increase the risk of high-grade disease, and in men, using statins for more than 4 years may increase the risk of clear cell RCC.
Article
Dermatology
M. Sachar, B. M. Lin, V. Wong, W. Li, V. Huang, J. Harris, K. Ezzedine, E. Cho, A. A. Qureshi
Summary: Regular use of acetaminophen may increase the risk of vitiligo in women.
AUSTRALASIAN JOURNAL OF DERMATOLOGY
(2023)
Article
Oncology
Shanshan Shi, Kai Wang, Tomotaka Ugai, Marios Giannakis, Jules Cazaubiel, Andrew T. Chan, Edward L. Giovannucci, Jonathan A. Nowak, Jeffrey A. Meyerhardt, Shuji Ogino, Mingyang Song
Summary: The association between vitamin C intake and colorectal cancer survival varies depending on the KRAS or BRAF mutation status, suggesting potential benefits for patients with mutated tumors.
BRITISH JOURNAL OF CANCER
(2023)
Letter
Dermatology
Erica M. Lin, Rachel K. Lim, Shirley Lin, Eunyoung Cho
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2023)
Review
Gastroenterology & Hepatology
Kosuke Mima, Tsuyoshi Hamada, Kentaro Inamura, Hideo Baba, Tomotaka Ugai, Shuji Ogino
Summary: There has been a significant increase in the incidence of early-onset cancers, particularly in the digestive system. While some of these cancers are associated with genetic variants, the majority are sporadic and multifactorial. Factors such as diets, lifestyle, environment, and the microbiome from early life to adulthood may play a role in the development of these cancers, but their exact contributions are still uncertain. To address this rising trend, interdisciplinary research approaches are needed to improve our understanding of the etiology and develop better prevention and treatment strategies.
Article
Medicine, General & Internal
Markus Dines Knudsen, Kai Wang, Liang Wang, Georgios Polychronidis, Paula Berstad, Kana Wu, Xiaosheng He, Dong Hang, Zhe Fang, Shuji Ogino, Andrew T. Chan, Edward Giovannucci, Molin Wang, Mingyang Song
Summary: This study developed an effective risk stratification tool for predicting post-polypectomy colorectal cancer (PPCRC) based on three population-based cohorts and validated the tool in a clinical cohort. By collecting detailed data on demographics, endoscopic history, polyp features, and lifestyle factors, the researchers developed an 11-predictor risk score for PPCRC, which can guide tailored colonoscopy surveillance strategies.
Review
Biology
Marcelo Paiva, Sara Yumeen, Benjamin J. Kahn, Hongmei Nan, Eunyoung Cho, Elie Saliba, Abrar Qureshi
Summary: Climate change and environmental health have an impact on agriculture and food supply, which ultimately affects population health. Research suggests that dietary nutrients, particularly those found in commonly consumed beverages, may influence the risk for skin cancer. Citrus juices and white wine may be associated with increased risk for skin cancer, while caffeinated beverages like coffee, tea, and cola may be associated with decreased risk for certain types of skin cancer.
YALE JOURNAL OF BIOLOGY AND MEDICINE
(2023)
Article
Dermatology
Isabelle H. Moseley, Elisabeth A. George, Megan M. Tran, Hemin Lee, Abrar A. Qureshi, Eunyoung Cho
Summary: This study estimated the prevalence of alopecia areata (AA) in different racial/ethnic and socio-economic groups. It found that individuals with skin of color had a higher prevalence of AA, while those with lower education and income levels and no health insurance had a lower prevalence.
ARCHIVES OF DERMATOLOGICAL RESEARCH
(2023)
Article
Dermatology
Isabelle H. Moseley, Jordan M. Thompson, Elisabeth A. George, Sara D. Ragi, Jae H. Kang, Anthony M. Reginato, Abrar Qureshi, Eunyoung Cho
Summary: This prospective study found that personal history of immune-mediated diseases is associated with an increased risk of alopecia areata (AA).
ARCHIVES OF DERMATOLOGICAL RESEARCH
(2023)
Article
Oncology
Yuxin Liu, Swati Bhardwaj, Keith Sigel, John Winters, Joseph Terlizzi, Michael M. Gaisa
Summary: This study investigated the prevalence and severity of anal HPV disease among MSM LWH under the age of 35, finding a high prevalence of HPV infection and precancer but no cases of invasive anal cancer. This supports the adoption of age-based anal cancer screening for this population.
INTERNATIONAL JOURNAL OF CANCER
(2024)
Correction
Oncology
J. Gu, S. Xie, S. Wang
INTERNATIONAL JOURNAL OF CANCER
(2024)