FAT1 is a novel upstream regulator of HIF1α and invasion of high grade glioma

miR-429 regulates the transition between Hypoxia-Inducible Factor (HIF)1A and HIF3A expression in human endothelial cells

(2016) Anna Janaszak-Jasiecka et al.   Scientific Reports

Knockdown of NAT12/NAA30 reduces tumorigenic features of glioblastoma-initiating cells

(2015) Awais A. Mughal et al.   Molecular Cancer

A Combined Gene Signature of Hypoxia and Notch Pathway in Human Glioblastoma and Its Prognostic Relevance

(2015) Khushboo Irshad et al.   PLoS One

Regulation and function of the atypical cadherin FAT1 in hepatocellular carcinoma

(2014) Daniela Valletta et al.   CARCINOGENESIS

MDM2 Regulates Hypoxic Hypoxia-inducible Factor 1α Stability in an E3 Ligase, Proteasome, and PTEN-Phosphatidylinositol 3-Kinase-AKT-dependent Manner

(2014) Shweta Joshi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation

(2013) Luc G T Morris et al.   NATURE GENETICS

FAT1 acts as an upstream regulator of oncogenic and inflammatory pathways, via PDCD4, in glioma cells

(2012) B Dikshit et al.   ONCOGENE

Hypoxia Induced Aggressiveness of Prostate Cancer Cells Is Linked with Deregulated Expression of VEGF, IL-6 and miRNAs That Are Attenuated by CDF

(2012) Bin Bao et al.   PLoS One

The Fat1 cadherin is overexpressed and an independent prognostic factor for survival in paired diagnosis–relapse samples of precursor B-cell acute lymphoblastic leukemia

(2011) C E de Bock et al.   LEUKEMIA

Knock down of HIF-1α in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres

(2010) Olga Méndez et al.   Molecular Cancer

Frequent loss of heterozygosity and altered expression of the candidate tumor suppressor gene 'FAT' in human astrocytic tumors

(2009) Kunzang Chosdol et al.   BMC CANCER

Atrophin Proteins Interact with the Fat1 Cadherin and Regulate Migration and Orientation in Vascular Smooth Muscle Cells

(2009) Rong Hou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sensing invasion: Cell surface receptors driving spreading of glioblastoma

(2009) Marcin Teodorczyk et al.   JOURNAL OF CELLULAR PHYSIOLOGY