MicroRNA-200c-targeted contactin 1 facilitates the replication of influenza A virus by accelerating the degradation of MAVS

The PB1 protein of influenza A virus inhibits the innate immune response by targeting MAVS for NBR1-mediated selective autophagic degradation

(2021) Yan Zeng et al.   PLoS Pathogens

Regulation of host and virus genes by neuronal miR-138 favours herpes simplex virus 1 latency

(2021) Boqiang Sun et al.   Nature Microbiology

Genetic and biological properties of H7N9 avian influenza viruses detected after application of the H7N9 poultry vaccine in China

(2021) Xin Yin et al.   PLoS Pathogens

A Novel Intronic Circular RNA Antagonizes Influenza Virus by Absorbing a microRNA That Degrades CREBBP and Accelerating IFN-β Production

(2021) Zhiyuan Qu et al.   mBio

A genome-wide CRISPR/Cas9 gene knockout screen identifies immunoglobulin superfamily DCC subclass member 4 as a key host factor that promotes influenza virus endocytosis

(2021) Yangming Song et al.   PLoS Pathogens

OTUB1 Is a Key Regulator of RIG-I-Dependent Immune Signaling and Is Targeted for Proteasomal Degradation by Influenza A NS1

(2020) Akhee Sabiha Jahan et al.   Cell Reports

Virus subtype-specific suppression of MAVS aggregation and activation by PB1-F2 protein of influenza A (H7N9) virus

(2020) Pak-Hin Hinson Cheung et al.   PLoS Pathogens

The Network of Interactions Between Classical Swine Fever Virus Nonstructural Protein p7 and Host Proteins

(2020) Jindai Fan et al.   Frontiers in Microbiology

miR-193b represses influenza A virus infection by inhibiting Wnt/β-catenin signaling

(2019) Xiaoyun Yang et al.   CELLULAR MICROBIOLOGY

The Otubain YOD1 Suppresses Aggregation and Activation of the Signaling Adaptor MAVS through Lys63-Linked Deubiquitination

(2019) Chang Liu et al.   JOURNAL OF IMMUNOLOGY

USP19 Inhibits TNF-α– and IL-1β–Triggered NF-κB Activation by Deubiquitinating TAK1

(2019) Cao-Qi Lei et al.   JOURNAL OF IMMUNOLOGY

Zika virus circumvents host innate immunity by targeting the adaptor proteins MAVS and MITA

(2019) Wenjiao Li et al.   FASEB JOURNAL

Cellular quality control by the ubiquitin-proteasome system and autophagy

(2019) Christian Pohl et al.   SCIENCE

Dual targeting of RIG-I and MAVS by MARCH5 mitochondria ubiquitin ligase in innate immunity

(2019) Yeon-Ji Park et al.   CELLULAR SIGNALLING

miR-200c targets nuclear factor IA to suppress HBV replication and gene expression via repressing HBV Enhancer I activity

(2018) Hui Tian et al.   BIOMEDICINE & PHARMACOTHERAPY

Overexpression of Contactin 1 promotes growth, migration and invasion in Hs578T breast cancer cells

(2018) Nan Chen et al.   BMC CELL BIOLOGY

A Naturally Occurring Deletion in the Effector Domain of H5N1 Swine Influenza Virus Nonstructural Protein 1 Regulates Viral Fitness and Host Innate Immunity

(2018) Junyong Wang et al.   JOURNAL OF VIROLOGY

Rapid Evolution of H7N9 Highly Pathogenic Viruses that Emerged in China in 2017

(2018) Jianzhong Shi et al.   Cell Host & Microbe

RACK1 attenuates RLR antiviral signaling by targeting VISA-TRAF complexes

(2018) Tao Xie et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Contactin-1/F3 Regulates Neuronal Migration and Morphogenesis Through Modulating RhoA Activity

(2018) Yi-An Chen et al.   Frontiers in Molecular Neuroscience

The Ubiquitin Code in the Ubiquitin-Proteasome System and Autophagy

(2017) Yong Tae Kwon et al.   TRENDS IN BIOCHEMICAL SCIENCES

USP13 negatively regulates antiviral responses by deubiquitinating STING

(2017) He Sun et al.   Nature Communications

GP73 represses host innate immune response to promote virus replication by facilitating MAVS and TRAF6 degradation

(2017) Xuewu Zhang et al.   PLoS Pathogens

miRNA-200c-3p is crucial in acute respiratory distress syndrome

(2017) Qiang Liu et al.   Cell Discovery

Neural Cell Adhesion Protein CNTN1 Promotes the Metastatic Progression of Prostate Cancer

(2016) Judy Yan et al.   CANCER RESEARCH

Duck Tembusu Virus Nonstructural Protein 1 Antagonizes IFN-β Signaling Pathways by Targeting VISA

(2016) Junyong Wang et al.   JOURNAL OF IMMUNOLOGY

The ubiquitin E3 ligase TRIM31 promotes aggregation and activation of the signaling adaptor MAVS through Lys63-linked polyubiquitination

(2016) Bingyu Liu et al.   NATURE IMMUNOLOGY

Genetic and biological characterization of two novel reassortant H5N6 swine influenza viruses in mice and chickens

(2015) Xuyong Li et al.   INFECTION GENETICS AND EVOLUTION

Induction of USP25 by viral infection promotes innate antiviral responses by mediating the stabilization of TRAF3 and TRAF6

(2015) Dandan Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mitochondrial ubiquitin ligase MARCH5 resolves MAVS aggregates during antiviral signalling

(2015) Young-Suk Yoo et al.   Nature Communications

Predicting effective microRNA target sites in mammalian mRNAs

(2015) Vikram Agarwal et al.   eLife

Smurf2 Negatively Modulates RIG-I-Dependent Antiviral Response by Targeting VISA/MAVS for Ubiquitination and Degradation

(2014) Y. Pan et al.   JOURNAL OF IMMUNOLOGY

miRNA-200c inhibits invasion and metastasis of human non-small cell lung cancer by directly targeting ubiquitin specific peptidase 25

(2014) Jing Li et al.   Molecular Cancer

Improved vectors and genome-wide libraries for CRISPR screening

(2014) Neville E Sanjana et al.   NATURE METHODS

Ferret H7N9 flu model questioned

(2013) Marc Lipsitch   NATURE

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

Enterovirus 71 Protease 2Apro Targets MAVS to Inhibit Anti-Viral Type I Interferon Responses

(2013) Bei Wang et al.   PLoS Pathogens

MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades

(2013) Siqi Liu et al.   eLife

F3/Contactin acts as a modulator of neurogenesis during cerebral cortex development

(2012) Antonella Bizzoca et al.   DEVELOPMENTAL BIOLOGY

MAVS Forms Functional Prion-like Aggregates to Activate and Propagate Antiviral Innate Immune Response

(2011) Fajian Hou et al.   CELL

Influenza A viruses: new research developments

(2011) Rafael A. Medina et al.   NATURE REVIEWS MICROBIOLOGY

Pathogen-Mediated Posttranslational Modifications: A Re-emerging Field

(2010) David Ribet et al.   CELL

TAX1BP1 and A20 Inhibit Antiviral Signaling by Targeting TBK1-IKKi Kinases

(2010) Kislay Parvatiyar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The E3 Ubiquitin Ligase RNF5 Targets Virus-Induced Signaling Adaptor for Ubiquitination and Degradation

(2010) B. Zhong et al.   JOURNAL OF IMMUNOLOGY

The Hepatitis B Virus X Protein Disrupts Innate Immunity by Downregulating Mitochondrial Antiviral Signaling Protein

(2010) C. Wei et al.   JOURNAL OF IMMUNOLOGY

The protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules

(2010) S. Bouyain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4

(2009) Fuping You et al.   NATURE IMMUNOLOGY

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) enhances invasiveness of lung cancer cells by up-regulating contactin-1 via the α7 nicotinic acetylcholine receptor/ERK signaling pathway

(2008) Yu-Hsuan Hung et al.   CHEMICO-BIOLOGICAL INTERACTIONS

RNA recognition and signal transduction by RIG-I-like receptors

(2008) Mitsutoshi Yoneyama et al.   IMMUNOLOGICAL REVIEWS

Contactin-1 Is a Functional Receptor for Neuroregulatory Chondroitin Sulfate-E

(2008) Tadahisa Mikami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY