Two oppositely-charged sf3b1 mutations cause defective development, impaired immune response, and aberrant selection of intronic branch sites in Drosophila
出版年份 2021 全文链接
标题
Two oppositely-charged sf3b1 mutations cause defective development, impaired immune response, and aberrant selection of intronic branch sites in Drosophila
作者
关键词
Drosophila melanogaster, Introns, Mutant strains, Climbing, Point mutation, Reverse transcriptase-polymerase chain reaction, Gene expression, Cancers and neoplasms
出版物
PLoS Genetics
Volume 17, Issue 11, Pages e1009861
出版商
Public Library of Science (PLoS)
发表日期
2021-11-02
DOI
10.1371/journal.pgen.1009861
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Contribution of Intellectual Disability–Related Genes to ADHD Risk and to Locomotor Activity in Drosophila
- (2020) Marieke Klein et al. AMERICAN JOURNAL OF PSYCHIATRY
- Clinical presentation and differential splicing of SRSF2, U2AF1 and SF3B1 mutations in patients with acute myeloid leukemia
- (2020) Stefanos A. Bamopoulos et al. LEUKEMIA
- Impact of cancer-associated mutations in Hsh155/SF3b1 HEAT repeats 9-12 on pre-mRNA splicing in Saccharomyces cerevisiae
- (2020) Harpreet Kaur et al. PLoS One
- Mutations in the RNA Splicing Factor SF3B1 Promote Tumorigenesis through MYC Stabilization
- (2020) Zhaoqi Liu et al. Cancer Discovery
- Targeted Next-Generation Sequencing of 117 Routine Clinical Samples Provides Further Insights into the Molecular Landscape of Uveal Melanoma
- (2020) Sophie Thornton et al. Cancers
- Normal Ethanol Sensitivity and Rapid Tolerance Require the G Protein Receptor Kinase 2 in Ellipsoid Body Neurons in Drosophila
- (2020) Yuan Yuan Kang et al. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
- Molecular architecture of the human 17S U2 snRNP
- (2020) Zhenwei Zhang et al. NATURE
- A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion
- (2019) Shanye Yin et al. CANCER CELL
- Mechanism of 5ʹ splice site transfer for human spliceosome activation
- (2019) Clément Charenton et al. SCIENCE
- Disease-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1
- (2019) Jian Zhang et al. MOLECULAR CELL
- CRISPR editing of sftb-1/SF3B1 in Caenorhabditis elegans allows the identification of synthetic interactions with cancer-related mutations and the chemical inhibition of splicing
- (2019) Xènia Serrat et al. PLoS Genetics
- Structure of the human activated spliceosome in three conformational states
- (2018) Xiaofeng Zhang et al. CELL RESEARCH
- The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations
- (2018) Liang Chen et al. MOLECULAR CELL
- Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
- (2018) Rui Bai et al. SCIENCE
- Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types
- (2018) Michael Seiler et al. Cell Reports
- Prognostic value and clinical feature of SF3B1 mutations in myelodysplastic syndromes: A meta-analysis
- (2018) Yaqiong Tang et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface
- (2018) Sarah Loerch et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mechanistic insights into precursor messenger RNA splicing by the spliceosome
- (2017) Yigong Shi NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia
- (2016) Lili Wang et al. CANCER CELL
- Physiologic Expression of Sf3b1 K700E Causes Impaired Erythropoiesis, Aberrant Splicing, and Sensitivity to Therapeutic Spliceosome Modulation
- (2016) Esther A. Obeng et al. CANCER CELL
- Spliceosomal component Sf3b1 is essential for hematopoietic differentiation in zebrafish
- (2016) Adriana De La Garza et al. EXPERIMENTAL HEMATOLOGY
- SF3B1/Hsh155 HEAT motif mutations affect interaction with the spliceosomal ATPase Prp5, resulting in altered branch site selectivity in pre-mRNA splicing
- (2016) Qing Tang et al. GENES & DEVELOPMENT
- Hemopoietic-specific Sf3b1-K700E knock-in mice display the splicing defect seen in human MDS but develop anemia without ring sideroblasts
- (2016) A Mupo et al. LEUKEMIA
- Molecular Architecture of SF3b and Structural Consequences of Its Cancer-Related Mutations
- (2016) Constantin Cretu et al. MOLECULAR CELL
- Cancer-associated SF3B1 mutants recognize otherwise inaccessible cryptic 3′ splice sites within RNA secondary structures
- (2016) A K Kesarwani et al. ONCOGENE
- Splicing-factor alterations in cancers
- (2016) Olga Anczuków et al. RNA
- Cancer-associated SF3B1 mutations affect alternative splicing by promoting alternative branchpoint usage
- (2016) Samar Alsafadi et al. Nature Communications
- Mutations driving CLL and their evolution in progression and relapse
- (2015) Dan A. Landau et al. NATURE
- HISAT: a fast spliced aligner with low memory requirements
- (2015) Daehwan Kim et al. NATURE METHODS
- RNA mis-splicing in disease
- (2015) Marina M. Scotti et al. NATURE REVIEWS GENETICS
- Aberrant RNA splicing in cancer; expression changes and driver mutations of splicing factor genes
- (2015) A Sveen et al. ONCOGENE
- Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3′ Splice Site Selection through Use of a Different Branch Point
- (2015) Rachel B. Darman et al. Cell Reports
- Transcriptome Sequencing Reveals Potential Mechanism of Cryptic 3’ Splice Site Selection in SF3B1-mutated Cancers
- (2015) Christopher DeBoever et al. PLoS Computational Biology
- HTSeq--a Python framework to work with high-throughput sequencing data
- (2014) S. Anders et al. BIOINFORMATICS
- The effect of neurospecific knockdown of candidate genes for locomotor behavior and sound production inDrosophila melanogaster
- (2014) Sergey A Fedotov et al. FLY
- Positive and negative gustatory inputs affect Drosophila lifespan partly in parallel to dFOXO signaling
- (2014) I. Ostojic et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data
- (2014) Shihao Shen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Skeletal muscle myogenesis is regulated by G protein-coupled receptor kinase 2
- (2014) Lucia Garcia-Guerra et al. Journal of Molecular Cell Biology
- Splicing factor mutations and cancer
- (2014) Kenichi Yoshida et al. Wiley Interdisciplinary Reviews-RNA
- Clinical and biological implications of driver mutations in myelodysplastic syndromes
- (2013) E. Papaemmanuil et al. BLOOD
- Landscape of genetic lesions in 944 patients with myelodysplastic syndromes
- (2013) T Haferlach et al. LEUKEMIA
- Exome sequencing identifies recurrent somatic mutations in EIF1AX and SF3B1 in uveal melanoma with disomy 3
- (2013) Marcel Martin et al. NATURE GENETICS
- Recurrent mutations at codon 625 of the splicing factor SF3B1 in uveal melanoma
- (2013) J William Harbour et al. NATURE GENETICS
- SF3B1 Mutations Are Associated with Alternative Splicing in Uveal Melanoma
- (2013) S. J. Furney et al. Cancer Discovery
- Misregulation of Pre-mRNA Alternative Splicing in Cancer
- (2013) J. Zhang et al. Cancer Discovery
- SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML)
- (2012) M. Meggendorfer et al. BLOOD
- Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing
- (2012) Marcin Imielinski et al. CELL
- The conserved transcription factor Mef2 has multiple roles in adult Drosophila musculature formation
- (2012) C. Soler et al. DEVELOPMENT
- The zebrafish sf3b1b460mutant reveals differential requirements for the sf3b1 pre-mRNA processing gene during neural crest development
- (2012) Min An et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
- The landscape of cancer genes and mutational processes in breast cancer
- (2012) Philip J. Stephens et al. NATURE
- Whole-genome analysis informs breast cancer response to aromatase inhibition
- (2012) Matthew J. Ellis et al. NATURE
- Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
- (2012) Andrew V. Biankin et al. NATURE
- A GAL4-Driver Line Resource for Drosophila Neurobiology
- (2012) Arnim Jenett et al. Cell Reports
- Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms
- (2011) L. Malcovati et al. BLOOD
- Mechanical analysis of Drosophila indirect flight and jump muscles
- (2011) Douglas M. Swank METHODS
- A U1-U2 snRNP Interaction Network during Intron Definition
- (2011) W. Shao et al. MOLECULAR AND CELLULAR BIOLOGY
- Frequent pathway mutations of splicing machinery in myelodysplasia
- (2011) Kenichi Yoshida et al. NATURE
- Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes
- (2011) Timothy A Graubert et al. NATURE GENETICS
- Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
- (2011) Víctor Quesada et al. NATURE GENETICS
- SomaticSF3B1Mutation in Myelodysplasia with Ring Sideroblasts
- (2011) E. Papaemmanuil et al. NEW ENGLAND JOURNAL OF MEDICINE
- SF3B1and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia
- (2011) Lili Wang et al. NEW ENGLAND JOURNAL OF MEDICINE
- Systematic genetic analysis of muscle morphogenesis and function in Drosophila
- (2010) Frank Schnorrer et al. NATURE
- Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing
- (2010) R. M. Lardelli et al. RNA
- Molecular Evolution and Functional Characterization of Drosophila Insulin-Like Peptides
- (2010) Sebastian Grönke et al. PLoS Genetics
- Regulation of cytochrome P450 expression in Drosophila: Genomic insights
- (2009) Maeva Giraudo et al. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
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