microRNA-142 guards against autoimmunity by controlling Treg cell homeostasis and function

miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity

(2019) Marcin Łyszkiewicz et al.   PLOS BIOLOGY

microRNA-142–mediated repression of phosphodiesterase 3B critically regulates peripheral immune tolerance

(2019) Nelomi Anandagoda et al.   JOURNAL OF CLINICAL INVESTIGATION

Blockade of miR-142-3p promotes anti-apoptotic and suppressive function by inducing KDM6A-mediated H3K27me3 demethylation in induced regulatory T cells

(2019) Ji Gao et al.   Cell Death & Disease

miR-142-3p regulates autophagy by targeting ATG16L1 in thymic-derived regulatory T cell (tTreg)

(2018) Yunjie Lu et al.   Cell Death & Disease

Excessive expression of miR-27 impairs Treg-mediated immunological tolerance

(2017) Leilani O. Cruz et al.   JOURNAL OF CLINICAL INVESTIGATION

Altered lymphopoiesis and immunodeficiency in miR-142 null mice

(2015) N. J. Kramer et al.   BLOOD

E3 Ubiquitin Ligase VHL Regulates Hypoxia-Inducible Factor-1α to Maintain Regulatory T Cell Stability and Suppressive Capacity

(2015) Jee H. Lee et al.   IMMUNITY

Mature T cell responses are controlled by microRNA-142

(2015) Yaping Sun et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-142-3p acts as an essential modulator of neutrophil development in zebrafish

(2014) H.-B. Fan et al.   BLOOD

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

Mononuclear phagocyte miRNome analysis identifies miR-142 as critical regulator of murine dendritic cell homeostasis

(2012) A. Mildner et al.   BLOOD

Transcriptome-wide miR-155 Binding Map Reveals Widespread Noncanonical MicroRNA Targeting

(2012) Gabriel B. Loeb et al.   MOLECULAR CELL

Differentiation and function of Foxp3+ effector regulatory T cells

(2012) Erika Cretney et al.   TRENDS IN IMMUNOLOGY

A Requisite Role for Induced Regulatory T Cells in Tolerance Based on Expanding Antigen Receptor Diversity

(2011) Dipica Haribhai et al.   IMMUNITY

SylArray: a web server for automated detection of miRNA effects from expression data

(2010) N. Bartonicek et al.   BIOINFORMATICS

Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses

(2010) Li-Fan Lu et al.   CELL

MicroRNA control of signal transduction

(2010) Masafumi Inui et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein

(2009) Li-Fan Lu et al.   IMMUNITY

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

(2009) J. Chen et al.   NUCLEIC ACIDS RESEARCH

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

miR-142-3p restricts cAMP production in CD4+CD25− T cells and CD4+CD25+ TREG cells by targeting AC9 mRNA

(2008) Bo Huang et al.   EMBO REPORTS

Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

(2008) Yuri P. Rubtsov et al.   IMMUNITY

The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease

(2008) Mark M.W. Chong et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dicer-dependent microRNA pathway safeguards regulatory T cell function

(2008) Adrian Liston et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity

(2008) Xuyu Zhou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulatory T Cells: Mechanisms of Differentiation and Function

(2007) Steven Z. Josefowicz et al.   Annual Review of Immunology