Article
Environmental Sciences
Xinzong Zhang, Zhaoyu Fan, Qiling Wang, Xinyi Deng, Ruijun Xu, Yingxin Li, Tingting Liu, Rui Wang, Chunxiang Shi, Suli Huang, Ziquan Lv, Gongbo Chen, Yong-Gang Duan, Yuewei Liu
Summary: This study reveals an association between ambient temperature and semen quality in South China, with higher temperatures leading to a reduction in semen quality. The findings indicate that a 5-degree Celsius increase in temperature during the 0-90 day period before ejaculation is associated with decreased sperm concentration, total sperm number, total motility, and normal sperm morphology. Furthermore, specific critical exposure windows of 10-14 days and 70-90 days before ejaculation were identified for sperm motility, count, and morphology.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Agriculture, Dairy & Animal Science
Carlota Quinones-Perez, Amparo Martinez, Isabel Ortiz, Francisco Crespo, Jose Luis Vega-Pla
Summary: Stallion infertility is a significant issue in the horse industry, and recent research has found that seminal microflora may play a role in sperm quality. This study identified correlations between the presence of certain bacteria families and sperm motility parameters, providing new insights for infertility treatment.
Article
Medicine, General & Internal
Qingtai Wang, Chengwen Que, Gangxin Chen
Summary: This study analyzed the effect of leukocyte elastase (LE) in semen on sperm quality and explored the reference range of normal LE levels in semen. The study found no significant difference in LE levels between normal semen and abnormal semen. According to different standards, a concentration of 600 ng/mL was determined as the appropriate threshold for LE in semen. The correlation between LE levels and sperm quality was not significant.
Review
Obstetrics & Gynecology
Lars Bjorndahl
Summary: The WHO laboratory manual for the examination and processing of human semen is a globally recognized authoritative source on semen examination techniques. It focuses on male infertility factors and medical assisted reproduction, with adjustments made to improve efficacy and user-friendliness, as well as incorporating more data on couples preparing for pregnancy.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Article
Obstetrics & Gynecology
Lars Bjorndahl, Jackson Kirkman Brown
Summary: The principles of basic semen investigation are crucial for obtaining reliable and internationally comparable results. However, many studies and practices in reproductive medicine fail to adhere to these principles, leading to a lack of comparable data and accuracy. To address this issue, the sixth edition of the WHO manual introduces revised methods and a complementary formal standard from the International Standards Organization. The new edition also reintroduces the four-category distinction of sperm motility and emphasizes the importance of semen examination for assessing male reproductive functions and overall male health.
FERTILITY AND STERILITY
(2022)
Article
Cell Biology
Francesco Manfrevola, Bruno Ferraro, Carolina Sellitto, Domenico Rocco, Silvia Fasano, Riccardo Pierantoni, Rosanna Chianese
Summary: The study reveals the important role of circular RNAs in human asthenozoospermia, involved in regulating the expression of genes related to sperm motility through competitive endogenous RNA networks.
Article
Endocrinology & Metabolism
Xianchun Fu, Jun Fang, Zhijun Dai, Mingyun Hong
Summary: This study found that Ureaplasma urealyticum infection is associated with semen quality and sperm morphology, leading to decreased male fertility.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Francesca Nicoli, Alessandro Prete, Fabrizia Citro, Alessandra Bertolotto, Michele Aragona, Giovanni de Gennaro, Stefano Del Prato, Cristina Bianchi
Summary: Pregnant women commonly consume non-nutritive-sweetened soft drinks, which is associated with an increased risk of gestational diabetes independently from traditional risk factors, as observed in this study of 376 pregnant women consecutively screened for gestational diabetes.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2021)
Article
Obstetrics & Gynecology
Ido Feferkorn, Liat Azani, Einav Kadour-Peero, Ranit Hizkiyahu, Guy Shrem, Mali Salmon-Divon, Michael H. Dahan
Summary: Significant geographic variations in sperm parameters were found in this study, suggesting the importance of considering regional reference ranges based on local experience and treatment outcomes.
FERTILITY AND STERILITY
(2022)
Article
Agriculture, Dairy & Animal Science
Ewa Lukaszewicz, Anna Jerysz, Artur Kowalczyk
Summary: The creation of genetic reserves for domesticated animal species and breeds has become a necessity in recent years. This study evaluated the quantitative and qualitative characteristics of semen collected through dorso-abdominal massage in six different goose breeds, and found that both breed and individual have an effect on semen traits.
REPRODUCTION IN DOMESTIC ANIMALS
(2022)
Article
Biology
Maria del Carmen Fuentes-Albero, Silvia Abril Sanchez, Jose Luis Ros-Santaella, Eliana Pintus, Chiara Luongo, Sara Ruiz Diaz, Carlos Barros Garcia, Maria Jesus Sanchez Calabuig, Daniel Garcia Parraga, Francisco Alberto Garcia Vazquez
Summary: Dolphins are well-adapted aquatic mammals in captivity and are ideal for studying their reproductive features for conservation programs. Sperm shape and dimensions differ between male dolphins and can be classified into subpopulations, which are influenced by testosterone levels and refrigeration. This study provides new insights into sperm competition in dolphins and has implications for other endangered aquatic mammalian species.
Article
Nutrition & Dietetics
Lana Vanderlee, Christine M. White, Sharon Kirkpatrick, Vicki L. Rynard, Alejandra Jauregui, Jean Adams, Gary Sacks, David Hammond
Summary: This study compared the consumption of commonly consumed beverages among adults in 5 countries, finding that individuals in Mexico and the USA had higher consumption of sugary drinks, while those in the UK were more likely to consume diet drinks.
JOURNAL OF NUTRITION
(2021)
Article
Agriculture, Dairy & Animal Science
Ewa Lukaszewicz, Artur Kowalczyk, Anna Jerysz
Summary: A study on the sperm quality of geese in Poland revealed significant differences in reproductive traits among different genetic groups. Attention should be paid to semen quality in order to avoid weakening the reproductive capacity of flocks covered by genetic resources protection programs.
Article
Agriculture, Dairy & Animal Science
Nicole Sugai, Stephen Werre, Julie Cecere, Orsolya Balogh
Summary: The study aimed to determine the clinically relevant centrifugation parameters for processing canine semen. It was hypothesized that higher gravitational force and longer centrifugation time would improve spermatozoa recovery rate but decrease semen quality. The results showed that centrifugation within the range of 400 g-900 g for 5-10 min is appropriate for processing canine semen.
Article
Endocrinology & Metabolism
Hongyi Yang, Yan Liu, Wenbin Niu, Zilan Yang, Yang Wang, Haixia Jin, Gang Li
Summary: This study aimed to evaluate the influence of abnormal semen parameters on embryo aneuploidy using a single nucleotide polymorphism microarray (SNP array). The results showed that abnormal semen parameters may affect embryo quality and increase the rate of aneuploidy in blastocyst chromosomes.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Obstetrics & Gynecology
Mette Jorgensen Langergaard, Andreas Ernst, Nis Brix, Anne Gaml-Sorensen, Sandra S. Tottenborg, Jens Peter E. Bonde, Gunnar Toft, Karin S. Hougaard, Cecilia H. Ramlau-Hansen
Summary: This study found that later maternal age at menarche was associated with impaired semen characteristics, lower testes volume, and altered levels of reproductive hormones in sons. However, earlier maternal age at menarche was not strongly associated with reproductive outcomes in sons. These findings may suggest a shared heritability or underlying epigenetic profile of reproductive health, but the exact mechanism remains unknown.
HUMAN REPRODUCTION
(2023)
Article
Obstetrics & Gynecology
Anne Gaml-Sorensen, Nis Brix, Sandra Sogaard Tottenborg, Karin Sorig Hougaard, Katia Keglberg Haervig, Jens Peter Ellekilde Bonde, Tine Brink Henriksen, Gunnar Toft, Cecilia Host Ramlau-Hansen
Summary: A study investigates the risk of selection bias in etiological studies on prenatal risk factors of poor male fecundity in a cohort of young men. The study finds that the risk of selection bias is limited despite a low participation rate.
HUMAN REPRODUCTION
(2023)
Article
Public, Environmental & Occupational Health
Anne Gaml-Sorensen, Nis Brix, Andreas Ernst, Lea Lykke Harrits Lunddorf, Christian Lindh, Gunnar Toft, Tine Brink Henriksen, Onyebuchi A. Arah, Cecilia Host Ramlau-Hansen
Summary: This study investigated whether the season of first trimester or maternal 25-hydroxyvitamin D-3 levels were associated with pubertal timing in children. The results showed that children of mothers who had their first trimester during November-April or had lower 25(OH)D-3 levels had earlier pubertal timing.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Anne Gaml-Sorensen, Nis Brix, Lea Lykke Harrits Lunddorf, Andreas Ernst, Birgit Bjerre Hoyer, Sjurdur Frodi Olsen, Charlotta Granstrom, Gunnar Toft, Tine Brink Henriksen, Cecilia Host Ramlau-Hansen
Summary: A study found that maternal intake of folate during pregnancy was not associated with pubertal timing in girls, but it was slightly later in boys. The minor delay is unlikely to be clinically significant.
PAEDIATRIC AND PERINATAL EPIDEMIOLOGY
(2023)
Article
Clinical Neurology
M. Meldgaard, R. S. Kristensen, W. J. Z'Graggen, S. V. Tan, K. Sondergaard, E. Qerama, H. Andersen, A. Fuglsang-Frederiksen, H. Tankisi
Summary: Objective: To investigate the pathophysiology of myopathies using MVRC and RAMP methodologies. Methods: qEMG, MVRC, and RAMP were conducted on 42 myopathy patients and 42 healthy controls. Results: Significant differences in MUP duration, MVRC supernormalities, and RAMP latencies were observed in myopathy patients compared to controls, particularly in non-inflammatory myopathy subtype. Conclusions: MVRC and RAMP parameters can differentiate between healthy individuals and myopathy patients, providing insights into the pathogenesis of myopathies.
CLINICAL NEUROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Louise F. Udholm, Ninna H. Ebdrup, Linn H. Arendt, Ulla B. Knudsen, Vibeke E. Hjortdal, Cecilia H. Ramlau-Hansen
Summary: This nationwide cohort study evaluated the risk of impaired fertility in women with congenital heart disease (CHD) compared with unaffected women. The results showed that women with CHD did not have an increased risk in time to pregnancy (TTP).
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Pernille Jul Clemmensen, Nis Brix, Jorg Schullehner, Andreas Ernst, Lea Lykke Harrits Lunddorf, Anne Ahrendt Bjerregaard, Thorhallur Ingi Halldorsson, Sjurdur Frodi Olsen, Birgitte Hansen, Leslie Thomas Stayner, Henrik Albert Kolstad, Torben Sigsgaard, Cecilia Host Ramlau-Hansen
Summary: This study investigated the association between prenatal exposure to nitrosatable drugs and timing of puberty, and found no significant association between the two. Sub-analyses examining different subtypes of nitrosatable drugs, dose-dependency, and the potential effect of maternal intake of nitrate, nitrite, and antioxidants also yielded null findings. This research suggests that prenatal exposure to nitrosatable drugs does not appear to impact the timing of puberty in children.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2023)
Article
Reproductive Biology
Anne Hjorth Thomsen, Anne Gaml-Sorensen, Nis Brix, Sandra Sogaard Tottenborg, Karin Sorig Hougaard, Andreas Ernst, Linn Hakonsen Arendt, Gunnar Toft, Jens Peter Bonde, Cecilia Host Ramlau-Hansen
Summary: Maternal alcohol intake in early pregnancy may be associated with biomarkers of fecundity in adult sons, especially in those whose mothers consumed more than 3 drinks per week and had 3 or more episodes of binge drinking during pregnancy. However, the effect estimates were generally small and inconsistent, with no indication of a dose-dependent association.
REPRODUCTIVE TOXICOLOGY
(2023)
Article
Nutrition & Dietetics
Anne Gaml-Sorensen, Nis Brix, Lea Lykke Harrits Lunddorf, Andreas Ernst, Birgit Bjerre Hoyer, Gunnar Toft, Tine Brink Henriksen, Cecilia Host Ramlau-Hansen
Summary: Maternal intake of vitamin D supplements may affect the timing of puberty in children, with a more significant impact observed in boys.
Article
Andrology
Andreas Ernst, Nis Brix, Anne Gaml-Sorensen, Linn Hakonsen Arendt, Gunnar Toft, Sandra Sogaard Tottenborg, Karin Soring Hougaard, Jens Peter Ellekilde Bonde, Cecilia Host Ramlau-Hansen
Summary: This study investigated the association between high parental age at birth and biomarkers of male fecundity. The results showed that sons of mothers aged 35 and above had lower sperm concentration and total sperm count. The analysis of parental age combinations also revealed a significant decrease in sperm concentration when both parents were aged 35 and above.
Review
Public, Environmental & Occupational Health
Mette J. Langergaard, Andreas Ernst, Nis Brix, Lea L. H. Lunddorf, Cecilia H. Ramlau-Hansen
Summary: The purpose of this study is to review recent epidemiological studies published from 2017 to 2022 on the potential associations between prenatal exposure to parental lifestyle factors, diseases, and medication use and pubertal development in sons. The reviewed studies found that maternal pre-pregnancy obesity and smoking during pregnancy may be associated with earlier pubertal development in sons, while the association between paternal obesity and timing of puberty was less clear. Maternal alcohol consumption may be associated with later pubertal development in sons. Maternal gestational diabetes mellitus was associated with faster pubertal development in terms of growth, but no association was found with other markers of pubertal timing. Recent studies also reported earlier timing of puberty in sons born to mothers with hyperthyroidism and mothers accidentally using oral contraceptives during early pregnancy. No other explored prenatal exposures were associated with pubertal development in sons.
CURRENT EPIDEMIOLOGY REPORTS
(2023)
Article
Obstetrics & Gynecology
Anne Gaml-Sorensen, Anne Hjorth Thomsen, Sandra Sogaard Tottenborg, Nis Brix, Karin Sorig Hougaard, Gunnar Toft, Siri Eldevik Haberg, Mikko Myrskyla, Jens Peter Bonde, Cecilia Host Ramlau-Hansen
Summary: The maternal pre-pregnancy BMI was associated with altered reproductive hormone profile in young adult sons, characterized by higher levels of estradiol, LH, and free androgen index, and lower levels of sex hormone-binding globulin. The effects of maternal pre-pregnancy BMI on hormone levels may be partly mediated by sons' birthweight, fat mass, and BMI.
HUMAN REPRODUCTION
(2023)