Arthritis flares mediated by tissue-resident memory T cells in the joint

Biological classification of childhood arthritis: roadmap to a molecular nomenclature

(2021) Peter A. Nigrovic et al.   Nature Reviews Rheumatology

Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses

(2020) Jun Siong Low et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Distinct fibroblast subsets drive inflammation and damage in arthritis

(2019) Adam P. Croft et al.   NATURE

Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry

(2019) Fan Zhang et al.   NATURE IMMUNOLOGY

Location, location, location: Tissue resident memory T cells in mice and humans

(2019) Peter A. Szabo et al.   Science Immunology

Integrin and transcriptomic profiles identify a distinctive synovial CD8+ T cell subpopulation in spondyloarthritis

(2019) Zoya Qaiyum et al.   ANNALS OF THE RHEUMATIC DISEASES

Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes

(2019) Myles J. Lewis et al.   Cell Reports

Tissue-resident memory T cells in tissue homeostasis, persistent infection, and cancer surveillance

(2018) Thomas Gebhardt et al.   IMMUNOLOGICAL REVIEWS

Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes

(2018) Rizi Ai et al.   Nature Communications

PD-1+CD8+ T cells are clonally expanding effectors in human chronic inflammation

(2018) Alessandra Petrelli et al.   JOURNAL OF CLINICAL INVESTIGATION

CD49a Expression Defines Tissue-Resident CD8 + T Cells Poised for Cytotoxic Function in Human Skin

(2017) Stanley Cheuk et al.   IMMUNITY

Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis

(2017) Deepak A. Rao et al.   NATURE

Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism

(2017) Youdong Pan et al.   NATURE

Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours

(2017) J. Justin Milner et al.   NATURE

Transcriptional Regulation of Tissue-Resident Lymphocytes

(2017) Laura K. Mackay et al.   TRENDS IN IMMUNOLOGY

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

(2017) Brahma V. Kumar et al.   Cell Reports

Review: Genetics and the Classification of Arthritis in Adults and Children

(2017) Peter A. Nigrovic et al.   Arthritis & Rheumatology

A High-Dimensional Atlas of Human T Cell Diversity Reveals Tissue-Specific Trafficking and Cytokine Signatures

(2016) Michael Thomas Wong et al.   IMMUNITY

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

(2016) L. K. Mackay et al.   SCIENCE

Bone Marrow T Cells and the Integrated Functions of Recirculating and Tissue-Resident Memory T Cells

(2016) Francesca Di Rosa et al.   Frontiers in Immunology

Cutting Edge: CD69 Interference with Sphingosine-1-Phosphate Receptor Function Regulates Peripheral T Cell Retention

(2015) Laura K. Mackay et al.   JOURNAL OF IMMUNOLOGY

The emerging role of resident memory T cells in protective immunity and inflammatory disease

(2015) Chang Ook Park et al.   NATURE MEDICINE

Human skin is protected by four functionally and phenotypically discrete populations of resident and recirculating memory T cells

(2015) Rei Watanabe et al.   Science Translational Medicine

Resident memory T cells in human health and disease

(2015) R. A. Clark   Science Translational Medicine

IL-1 receptor antagonist-deficient mice develop autoimmune arthritis due to intrinsic activation of IL-17-producing CCR2+Vγ6+γδ T cells

(2015) Aoi Akitsu et al.   Nature Communications

Fine Mapping Seronegative and Seropositive Rheumatoid Arthritis to Shared and Distinct HLA Alleles by Adjusting for the Effects of Heterogeneity

(2014) Buhm Han et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The global burden of rheumatoid arthritis: estimates from the Global Burden of Disease 2010 study

(2014) Marita Cross et al.   ANNALS OF THE RHEUMATIC DISEASES

Resident memory CD8 T cells trigger protective innate and adaptive immune responses

(2014) J. M. Schenkel et al.   SCIENCE

Identification of rheumatoid arthritis and osteoarthritis patients by transcriptome-based rule set generation

(2014) Dirk Woetzel et al.   ARTHRITIS RESEARCH & THERAPY

Nonclassical Ly6C− Monocytes Drive the Development of Inflammatory Arthritis in Mice

(2014) Alexander V. Misharin et al.   Cell Reports

Sensing and alarm function of resident memory CD8+ T cells

(2013) Jason M Schenkel et al.   NATURE IMMUNOLOGY

The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin

(2013) Laura K Mackay et al.   NATURE IMMUNOLOGY

Human Epidermal Langerhans Cells Maintain Immune Homeostasis in Skin by Activating Skin Resident Regulatory T Cells

(2012) Julien Seneschal et al.   IMMUNITY

Tissue Exit: a Novel Control Point in the Accumulation of Antigen-Specific CD8 T Cells in the Influenza A Virus-Infected Lung

(2012) S. Jennrich et al.   JOURNAL OF VIROLOGY

Skin infection generates non-migratory memory CD8+ TRM cells providing global skin immunity

(2012) Xiaodong Jiang et al.   NATURE

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

(2012) Soumya Raychaudhuri et al.   NATURE GENETICS

Skin Effector Memory T Cells Do Not Recirculate and Provide Immune Protection in Alemtuzumab-Treated CTCL Patients

(2012) R. A. Clark et al.   Science Translational Medicine

Sustained rheumatoid arthritis remission is uncommon in clinical practice

(2012) Femke HM Prince et al.   ARTHRITIS RESEARCH & THERAPY

Local immunity by tissue-resident CD8+ memory T cells

(2012) Thomas Gebhardt et al.   Frontiers in Immunology

Cutting Edge: Regulator of G Protein Signaling-1 Selectively Regulates Gut T Cell Trafficking and Colitic Potential

(2011) D. L. Gibbons et al.   JOURNAL OF IMMUNOLOGY

Resident Memory T Cells (TRM) Are Abundant in Human Lung: Diversity, Function, and Antigen Specificity

(2011) Rahul Purwar et al.   PLoS One

E-cadherin promotes accumulation of a unique memory CD8 T-cell population in murine salivary glands

(2011) M. Hofmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Supplementation of diet with krill oil protects against experimental rheumatoid arthritis

(2010) Michelle Ierna et al.   BMC MUSCULOSKELETAL DISORDERS

Molecular signatures and new candidates to target the pathogenesis of rheumatoid arthritis

(2010) U. Ungethuem et al.   PHYSIOLOGICAL GENOMICS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH