The Emulsifier Carboxymethylcellulose Induces More Aggressive Colitis in Humanized Mice with Inflammatory Bowel Disease Microbiota Than Polysorbate-80

Rationally designed bacterial consortia to treat chronic immune-mediated colitis and restore intestinal homeostasis

(2021) Daniel van der Lelie et al.   Nature Communications

Strategies to Dissect Host-Microbial Immune Interactions That Determine Mucosal Homeostasis vs. Intestinal Inflammation in Gnotobiotic Mice

(2020) Allison R. Rogala et al.   Frontiers in Immunology

Fecal Microbiota Alterations Associated With Clinical and Endoscopic Response to Infliximab Therapy in Crohn’s Disease

(2020) Xiaojun Zhuang et al.   INFLAMMATORY BOWEL DISEASES

Emulsifiers Impact Colonic Length in Mice and Emulsifier Restriction is Feasible in People with Crohn’s Disease

(2020) Alicia M. Sandall et al.   Nutrients

Dietary Emulsifiers Directly Impact Adherent-Invasive E. coli Gene Expression to Drive Chronic Intestinal Inflammation

(2020) Emilie Viennois et al.   Cell Reports

Food additive emulsifiers and their impact on gut microbiome, permeability and inflammation: mechanistic insights in inflammatory bowel disease

(2020) Aaron S Bancil et al.   Journal of Crohns & Colitis

Dietary emulsifiers consumption alters anxiety-like and social-related behaviors in mice in a sex-dependent manner

(2019) Mary K. Holder et al.   Scientific Reports

Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

(2019) Jason Lloyd-Price et al.   NATURE

Crohn’s Disease Exclusion Diet Plus Partial Enteral Nutrition Induces Sustained Remission in a Randomized Controlled Trial

(2019) Arie Levine et al.   GASTROENTEROLOGY

Microbiota maintain colonic homeostasis by activating TLR2/MyD88/PI3K signaling in IL-10–producing regulatory B cells

(2019) Yoshiyuki Mishima et al.   JOURNAL OF CLINICAL INVESTIGATION

Impact of Food Additives on Gut Homeostasis

(2019) Laudisi et al.   Nutrients

Urbanization and the gut microbiota in health and inflammatory bowel disease

(2018) Tao Zuo et al.   Nature Reviews Gastroenterology & Hepatology

Humanizing the gut microbiota of mice: Opportunities and challenges

(2018) Randi Lundberg   LABORATORY ANIMALS

Dietary Exposures to Common Emulsifiers and Their Impact on the Gut Microbiota: Is There a Cause for Concern?

(2018) Trung D. Vo et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Species-level functional profiling of metagenomes and metatranscriptomes

(2018) Eric A. Franzosa et al.   NATURE METHODS

Roles for Intestinal Bacteria, Viruses, and Fungi in Pathogenesis of Inflammatory Bowel Diseases and Therapeutic Approaches

(2017) R. Balfour Sartor et al.   GASTROENTEROLOGY

Diet as a Trigger or Therapy for Inflammatory Bowel Diseases

(2017) James D. Lewis et al.   GASTROENTEROLOGY

Dietary emulsifiers directly alter human microbiota composition and gene expression ex vivo potentiating intestinal inflammation

(2017) Benoit Chassaing et al.   GUT

Dietary Therapy With the Crohn’s Disease Exclusion Diet is a Successful Strategy for Induction of Remission in Children and Adults Failing Biological Therapy

(2017) Rotem Sigall Boneh et al.   Journal of Crohns & Colitis

Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation

(2017) Koji Atarashi et al.   SCIENCE

A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients

(2017) Andrew Brantley Hall et al.   Genome Medicine

Dietary Emulsifier–Induced Low-Grade Inflammation Promotes Colon Carcinogenesis

(2016) Emilie Viennois et al.   CANCER RESEARCH

Lipocalin 2 Protects from Inflammation and Tumorigenesis Associated with Gut Microbiota Alterations

(2016) Alexander R. Moschen et al.   Cell Host & Microbe

Bifidobacteria and Butyrate-Producing Colon Bacteria: Importance and Strategies for Their Stimulation in the Human Gut

(2016) Audrey Rivière et al.   Frontiers in Microbiology

Metagenomic Analysis of Microbiome in Colon Tissue from Subjects with Inflammatory Bowel Diseases Reveals Interplay of Viruses and Bacteria

(2015) Weiwei Wang et al.   INFLAMMATORY BOWEL DISEASES

Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome

(2015) Benoit Chassaing et al.   NATURE

The Treatment-Naive Microbiome in New-Onset Crohn’s Disease

(2014) Dirk Gevers et al.   Cell Host & Microbe

Lipocalin 2 Expression and Secretion Is Highly Regulated by Metabolic Stress, Cytokines, and Nutrients in Adipocytes

(2014) Yuanyuan Zhang et al.   PLoS One

Antigen-Presenting Cell Production of IL-10 Inhibits T-Helper 1 and 17 Cell Responses and Suppresses Colitis in Mice

(2011) Bo Liu et al.   GASTROENTEROLOGY

Gut Microbiota and Inflammation

(2011) Asa Hakansson et al.   Nutrients

Mucosal T cells in gut homeostasis and inflammation

(2010) Femke van Wijk et al.   Expert Review of Clinical Immunology

Translocation of Crohn's disease Escherichia coli across M-cells: contrasting effects of soluble plant fibres and emulsifiers

(2010) C. L. Roberts et al.   GUT

Upregulation of T-bet and tight junction molecules by Bifidobactrium longum improves colonic inflammation of ulcerative colitis

(2009) Yasuhiro Takeda et al.   INFLAMMATORY BOWEL DISEASES