期刊
NUTRIENTS
卷 14, 期 1, 页码 -出版社
MDPI
DOI: 10.3390/nu14010103
关键词
metabolic-associated fatty liver disease; diabetes mellitus; cardiovascular disease; fructose; microbiota
Non-alcoholic fatty liver disease (NAFLD) is a common condition associated with type 2 diabetes (T2DM) and cardiovascular disease (CVD). The new term metabolic-associated fatty liver disease (MAFLD) highlights the bidirectional relationships between NAFLD, T2DM, and CVD. Lifestyle changes and targeting the gut microbiota may be important for NAFLD treatment.
Non-alcoholic fatty liver disease (NAFLD) is an increasingly common condition associated with type 2 diabetes (T2DM) and cardiovascular disease (CVD). Since systemic metabolic dysfunction underlies NAFLD, the current nomenclature has been revised, and the term metabolic-associated fatty liver disease (MAFLD) has been proposed. The new definition emphasizes the bidirectional relationships and increases awareness in looking for fatty liver disease among patients with T2DM and CVD or its risk factors, as well as looking for these diseases among patients with NAFLD. The most recommended treatment method of NAFLD is lifestyle changes, including dietary fructose limitation, although other treatment methods of NAFLD have recently emerged and are being studied. Given the focus on the liver-gut axis targeting, bacteria may also be a future aim of NAFLD treatment given the microbiome signatures discriminating healthy individuals from those with NAFLD. In this review article, we will provide an overview of the associations of fructose consumption, gut microbiota, diabetes, and CVD in patients with NAFLD.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据