Article
Immunology
Ulrika Snygg-Martin, Kok Wai Giang, Mikael Dellborg, Josefina Robertson, Zacharias Mandalenakis
Summary: Patients with congenital heart disease have a higher cumulative incidence of infective endocarditis compared to controls, and this incidence increases with age. The incidence of infective endocarditis varies by age but not by birth year.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Multidisciplinary Sciences
Siegfried Geyer, Katharina Fleig, Kambiz Norozi, Lena Roebbel, Thomas Paul, Matthias Mueller, Claudia Dellas
Summary: Patients of congenital heart disease surgery have good prospects for reaching old age, and the educational and occupational performance of patients over 15 years was examined. While some patients retired prematurely or never entered the labour force, their educational and occupational careers proceeded more favorably than expected.
Article
Nutrition & Dietetics
Ming-Xin Yan, Yan Zhao, Dou-Dou Zhao, Shao-Nong Dang, Ruo Zhang, Xin-Yu Duan, Pei-Xi Rong, Yu-Song Dang, Lei-Lei Pei, Peng-Fei Qu
Summary: This study found that supplementation of folic acid and iron during pregnancy can reduce the risk of congenital heart disease in offspring. The study also confirmed a significant multiplicative interaction between folic acid and iron nutrition in reducing the risk of congenital heart disease in offspring.
Article
Environmental Sciences
Doudou Zhao, Leqian Guo, Ruo Zhang, Qixia Zhu, Hongli Wang, Rong Liu, Hong Yan, Shaonong Dang
Summary: Exposure to certain electrical appliances during early pregnancy was associated with a higher risk of CHD, while wearing a radiation protection suit was linked to a lower risk of CHD. Women should reduce the use of electrical appliances before and during pregnancy to minimize the risk.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Cardiac & Cardiovascular Systems
Kok Wai Giang, Maria Fedchenko, Mikael Dellborg, Peter Eriksson, Zacharias Mandalenakis
Summary: Patients with congenital heart disease have a 5-fold higher risk of developing index ischemic stroke compared with controls, but they have a 34% lower risk of recurrent stroke and a 47% lower risk of all-cause mortality after index stroke.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Nutrition & Dietetics
Letao Chen, Tubao Yang, Tingting Wang, Mengting Sun, Jiabi Qin
Summary: This study found an association between maternal FA supplementation and non-chromosomal congenital heart disease (CHD) in offspring. Specific polymorphisms of the GATA4 gene were also related to CHD. Additionally, there was a gene-environment interaction between specific GATA4 gene polymorphisms and FA supplementation before/during pregnancy, which increased the risk of CHD.
Article
Biochemistry & Molecular Biology
Maria C. Escobar-Diaz, Miriam Perez-Cruz, Miguel Arraez, Mari-Merce Cascant-Vilaplana, Abel Albiach-Delgado, Julia Kuligowski, Maximo Vento, Narcis Masoller, Maria Dolores Gomez-Roig, Olga Gomez, Joan Sanchez-de-Toledo, Marta Camprubi-Camprubi
Summary: Fetuses with congenital heart disease (CHD) may experience circulatory changes affecting normal brain development. Research found that CHD fetuses had higher levels of oxidative stress biomarkers (OSB) that correlated with expected cyanosis levels and malnutrition.
Article
Public, Environmental & Occupational Health
Marie Tindborg, Anders Koch, Mikael Andersson, Klaus Juul, Uka Wilhjelm Geisler, Bolette Soborg, Sascha Wilk Michelsen
Summary: The incidence rates of heart disease (HD) and congenital heart disease (CHD) were compared between young Inuit populations in Greenland and Denmark. It was found that the incidence rate of HD was lower in Greenland compared to Denmark, while the incidence rates of CHD were similar in both countries. Individuals of Inuit/mixed ethnicity had a higher risk of both HD and CHD compared to non-Inuit individuals in both countries.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Environmental Sciences
Huanhuan Zhang, Xiaoan Zhang, Xin Zhao, Guomei Cheng, Hui Chang, Xiaofang Ye, Jingzhe Wang, Zengli Yu, Qiong Wang, Cunrui Huang
Summary: In Henan, China, exposure to CO in the first and second trimester was associated with an increased risk of overall CHDs. Additionally, NO2 and CO in the first trimester, PM2.5 and PM10 in the second trimester were linked to a higher risk of ASD, with susceptible windows occurring mainly in the 1st-6th gestational weeks. No positive association was found between air pollution and tetralogy of Fallot.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Pediatrics
Prachi Kukshal, Radha O. Joshi, Ajay Kumar, Shadab Ahamad, Prabhatha Rashmi Murthy, Yogesh Sathe, Krishna Manohar, Soma Guhathakurta, Subramanian Chellappan
Summary: This study investigated the association between Caucasian SNPs and congenital heart diseases (CHDs) in a population from northern India. The study found that some SNPs were strongly correlated with disease manifestation. The findings partly replicated the results of Caucasian studies, suggesting the contribution of genetic, environmental, and sociodemographic factors in this population's CHDs.
Article
Medicine, General & Internal
Jue Seong, Jin-Man Jung, Jongun Choi, Woo-Keun Seo, Hong Ju Shin
Summary: This study evaluated the prevalence of vascular events and all-cause mortality in Korean patients with CHD, finding that CHD is a significant risk factor for cardiovascular events and mortality.
YONSEI MEDICAL JOURNAL
(2022)
Article
Environmental Sciences
Pengfei Qu, Doudou Zhao, Mingxin Yan, Danmeng Liu, Ruo Zhang, Shanshan Li, Leilei Pei, Hong Yan, Lingxia Zeng, Shaonong Dang
Summary: This study aimed to investigate the association between maternal exposure to housing renovation during the periconceptional period and isolated congenital heart disease (CHD) in infants. A multi-hospitals case-control study was conducted, and it was found that maternal exposure to home improvement projects was associated with an increased risk of isolated CHD in offspring.
ENVIRONMENTAL HEALTH
(2023)
Article
Cardiac & Cardiovascular Systems
DanQing Hu, TingXiang Lan, YiFan Chen, LinYan Chen, JinGuo Li, XuDong Sun, Hua Chen, Jun Fang
Summary: Based on a Chinese echocardiography database, this study analyzed the observed rate and spectrum changes of congenital heart disease (CHD) in China over the past 18 years, with a focus on congenital aortic valve malformation (CAVM) and Adult CHD (ACHD). The study found a decrease in the observed rate of Total CHD and proportion of Complex CHD, an increase in the proportion of Simple CHD and ACHD (including CAVM and CAVM with aortic stenosis), and an increase in the proportion of CHD patients receiving intervention.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Yinyu Yang, Yibei Wu, Wen Zhang, Qing Cao, Haibo Zhang, Hao Zhang, Wei Dong
Summary: This study analyzed the clinical characteristics and prognostic factors of SARS-CoV-2 Omicron variant infections in children with congenital heart disease. The study found that these infections mostly presented with mild upper respiratory tract symptoms and negative or mildly changed chest imaging in these vulnerable patients. Through appropriate treatment of the underlying disease in the quarantine ward, patients might obtain good outcomes, even after long periods of hospitalization.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Environmental Sciences
Meixian Wang, Yan Tian, Ping Yu, Nana Li, Ying Deng, Lu Li, Hong Kang, Dapeng Chen, Hui Wang, Zhen Liu, Juan Liang
Summary: The study revealed a correlation between maternal manganese and iron concentrations and the risk of CHD among infants, with a potential higher risk associated with concurrent high levels of manganese and iron. Excessive manganese concentration in pregnant women was linked to a significantly increased risk of CHDs. Additionally, high maternal iron status was also found to correlate with CHDs, but no interaction between maternal manganese and iron concentrations was observed in the study.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Jing Li, Yujiao Du, Fengyi Qu, Hui Jing, Hong Yan, Shaonong Dang
Summary: This study aimed to assess the association between maternal exposure to second-hand tobacco smoke (SHS) and birth defects in a Chinese population. The results showed that pregnant women exposed to SHS had a 58% increased risk of overall birth defects and a 75% increased risk of circulatory system defects. The risk of overall birth defects also increased with the frequency of exposure. Sensitivity analyses confirmed the robustness of the findings.
JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE
(2022)
Article
Nutrition & Dietetics
Danmeng Liu, Shanshan Li, Binyan Zhang, Yijun Kang, Yue Cheng, Lingxia Zeng, Fangyao Chen, Baibing Mi, Pengfei Qu, Doudou Zhao, Zhonghai Zhu, Hong Yan, Duolao Wang, Shaonong Dang
Summary: This study reveals that maternal hemoglobin concentration during different trimesters of pregnancy is associated with neonatal birth weight, low birth weight (LBW), and small for gestational age (SGA). Both low and high hemoglobin concentrations in the third trimester can have adverse effects on fetal weight growth and increase the risks of LBW and SGA, respectively.
Article
Nutrition & Dietetics
Shanshan Li, Danmeng Liu, Yijun Kang, Pengfei Qu, Baibing Mi, Zhonghai Zhu, Lixin Han, Yaling Zhao, Fangyao Chen, Leilei Pei, Lingxia Zeng, Duolao Wang, Hong Yan, Shaonong Dang
Summary: This study aimed to investigate the relationship between maternal dietary pattern, B vitamins variation during pregnancy, and birth outcomes. The study found that a high B-vitamin dietary pattern was associated with higher birth weight and lower risk of SGA.
Article
Nutrition & Dietetics
Miaojia Yan, Yezhou Liu, Lichen Wu, Huimeng Liu, Yutong Wang, Fangyao Chen, Leilei Pei, Yaling Zhao, Lingxia Zeng, Shaonong Dang, Hong Yan, Baibing Mi
Summary: This study investigated the association between dietary purine intake and mortality among Chinese adults. The results showed an inverse association between purine intake and mortality, especially for plant-derived purine. A U-shaped relationship between purine intake and mortality was observed in males, while there was no significant dose-response relationship in females.
Article
Nutrition & Dietetics
Jiaomei Yang, Yijun Kang, Qianqian Chang, Binyan Zhang, Xin Liu, Lingxia Zeng, Hong Yan, Shaonong Dang
Summary: This study investigated the associations between maternal total, dietary, and supplemental intakes of zinc, copper, and selenium during pregnancy and congenital heart defects (CHDs). The results showed that higher intakes of zinc and selenium during pregnancy were associated with a reduced risk of CHDs, highlighting the importance of promoting zinc and selenium intakes in reducing the incidence of CHDs in the Chinese population.
Article
Environmental Sciences
Pengfei Qu, Doudou Zhao, Mingxin Yan, Danmeng Liu, Leilei Pei, Lingxia Zeng, Hong Yan, Shaonong Dang
Summary: This study developed a nomogram risk model for the assessment of any type of birth defect risk in the Chinese population. Factors such as household registration, history of miscarriages, family history of birth defects, infection, medication, pesticide exposure, folic acid supplementation, and single/twin pregnancy were found to be significant in the occurrence of birth defects.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Nutrition & Dietetics
Ming-Xin Yan, Yan Zhao, Dou-Dou Zhao, Shao-Nong Dang, Ruo Zhang, Xin-Yu Duan, Pei-Xi Rong, Yu-Song Dang, Lei-Lei Pei, Peng-Fei Qu
Summary: This study found that supplementation of folic acid and iron during pregnancy can reduce the risk of congenital heart disease in offspring. The study also confirmed a significant multiplicative interaction between folic acid and iron nutrition in reducing the risk of congenital heart disease in offspring.
Article
Nutrition & Dietetics
Jiaomei Yang, Qianqian Chang, Shaonong Dang, Xin Liu, Lingxia Zeng, Hong Yan
Summary: Limited studies have explored the relationship between maternal dietary quality and congenital heart defects (CHD) in the Chinese population. This case-control study found that pregnant women with higher dietary quality scores had a lower risk of fetal CHD. The inverse associations were stronger among women with lower education levels or living in rural areas. Maternal dietary quality scores had good predictive values for CHD.
Article
Nutrition & Dietetics
Binyan Zhang, Baibing Mi, Danmeng Liu, Huimeng Liu, Yutong Wang, Guoshuai Shi, Hui Jing, Yijun Kang, Jiaomei Yang, Shaonong Dang, Hong Yan
Summary: This study aimed to explore the association between maternity formula supplementation and small for gestational age (SGA) status in Chinese newborns. The results showed that there was no significant association between maternal formula supplementation during pregnancy and the risk of total SGA birth. However, for twins, maternity formula supplementation during pregnancy was associated with a lower risk of SGA birth, especially when supplemented during the first trimester.
Article
Nutrition & Dietetics
Kun Xu, Binyan Zhang, Yezhou Liu, Baibing Mi, Yutong Wang, Yuefan Shen, Guoshuai Shi, Shaonong Dang, Xin Liu, Hong Yan
Summary: This study investigated the association between staple food preference and obesity phenotypes in the Northwest Chinese population. The findings suggest that rice preference may be associated with lower odds ratios of excessive body fat and central obesity, compared with wheat preference. Similar inverse associations were observed in participants with normal body mass index.
Article
Cardiac & Cardiovascular Systems
Huimeng Liu, Yutong Wang, Binyan Zhang, Yating Huo, Suixia Cao, Jingchun Liu, Lingxia Zeng, Hong Yan, Shaonong Dang, Baibing Mi
Summary: This study suggests that a preference for stronger tastes of salty, sour, and spicy may be associated with an increased risk of hypertension, especially in females. This is possibly due to an increase in diastolic blood pressure. Therefore, it is encouraged for people to modify their dietary preferences towards a bland taste.
INTERNATIONAL JOURNAL OF HYPERTENSION
(2022)
Article
Nutrition & Dietetics
Jiaomei Yang, Qianqian Chang, Qiancheng Du, Shaonong Dang, Lingxia Zeng, Hong Yan
Summary: This study explored the relationship between diet-related inflammation during pregnancy and congenital heart defects (CHD). The findings revealed that a higher dietary inflammation index (DII) during pregnancy was associated with an increased risk of CHD in the offspring.
Article
Nutrition & Dietetics
Yating Huo, Suixia Cao, Jingchun Liu, Binyan Zhang, Kun Xu, Yutong Wang, Huimeng Liu, Peiying Yang, Lingxia Zeng, Hong Yan, Shaonong Dang, Baibing Mi
Summary: This study investigated the association between a plant-based diet and metabolic syndrome (MetS) in Chinese adults. The findings suggest a possible causal relationship between a healthy plant-based diet and a reduced risk of MetS, particularly abdominal obesity. BMI was found to mediate the relationship between a healthy plant-based diet and MetS. Controlling early dietary patterns and BMI may help reduce the risk of MetS.
Article
Nutrition & Dietetics
Hui Jing, Yuxin Teng, Samuel Chacha, Ziping Wang, Guoshuai Shi, Baibing Mi, Binyan Zhang, Jiaxin Cai, Yezhou Liu, Qiang Li, Yuan Shen, Jiaomei Yang, Yijun Kang, Shanshan Li, Danmeng Liu, Duolao Wang, Hong Yan, Shaonong Dang
Summary: This study investigates the impact of the diversity of animal foods on the health-related quality of life (HRQoL) among residents. The results show that a diverse intake of animal-sourced foods is positively associated with better HRQoL, particularly for men.
Article
Obstetrics & Gynecology
Yujiao Du, Jing Li, Pengfei Qu, Shaonong Dang
Summary: Deficiency in vitamin B-12 and folate in Chinese women during late pregnancy is prevalent. The nutritional status of these two vitamins in umbilical cord serum is nonlinearly correlated with that in maternal serum. Folic acid supplementation should be accompanied by vitamin B-12 to improve the status of both vitamins during pregnancy.
INTERNATIONAL JOURNAL OF WOMENS HEALTH
(2023)
