A method of separating extracellular vesicles from blood shows potential clinical translation, and reveals extracellular vesicle cargo gremlin-1 as a diagnostic biomarker

Gremlin-1 augments the oestrogen-related receptor α signalling through EGFR activation: implications for the progression of breast cancer

(2020) Sin-Aye Park et al.   BRITISH JOURNAL OF CANCER

Gremlin-1 activates Akt/STAT3 signaling, which increases the glycolysis rate in breast cancer cells

(2020) Na Hui Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Extracellular vesicles in blood: are they viable as diagnostic and predictive tools in breast cancer?

(2020) Róisín Daly et al.   DRUG DISCOVERY TODAY

Gremlin-1 Promotes Metastasis of Breast Cancer Cells by Activating STAT3-MMP13 Signaling Pathway

(2020) Nam Ji Sung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Polyethylene glycol improves current methods for circulating extracellular vesicle-derived DNA isolation

(2019) N. García-Romero et al.   Journal of Translational Medicine

GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients

(2019) Ulrike Neckmann et al.   Cell Communication and Signaling

Detailed analysis of the plasma extracellular vesicle proteome after separation from lipoproteins

(2018) Nasibeh Karimi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Expanding on Exosomes and Ectosomes in Cancer

(2015) Lorraine O’Driscoll   NEW ENGLAND JOURNAL OF MEDICINE

miR-134 in extracellular vesicles reduces triple-negative breast cancer aggression and increases drug sensitivity

(2015) Keith O’Brien et al.   Oncotarget

Exosomes from triple-negative breast cancer cells can transfer phenotypic traits representing their cells of origin to secondary cells

(2013) Keith O’Brien et al.   EUROPEAN JOURNAL OF CANCER

Do serum biomarkers really measure breast cancer?

(2009) Jonathan L Jesneck et al.   BMC CANCER