Lung directed antibody gene transfer confers protection against SARS-CoV-2 infection

K18-hACE2 mice develop respiratory disease resembling severe COVID-19

(2021) Claude Kwe Yinda et al.   PLoS Pathogens

Prevalence of neutralising antibodies against SARS-CoV-2 in acute infection and convalescence: A systematic review and meta-analysis

(2021) Helen R. Savage et al.   PLoS Neglected Tropical Diseases

Intranasal gene therapy to prevent infection by SARS-CoV-2 variants

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Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody

(2020) Xiaolong Tian et al.   Emerging Microbes & Infections

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

A Mouse Model of SARS-CoV-2 Infection and Pathogenesis

(2020) Shi-Hui Sun et al.   Cell Host & Microbe

Protection From Influenza by Intramuscular Gene Vector Delivery of a Broadly Neutralizing Nanobody Does Not Depend on Antibody Dependent Cellular Cytotoxicity

(2020) Joanne Marie M. Del Rosario et al.   Frontiers in Immunology

Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment

(2020) Jing Sun et al.   CELL

Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling

(2020) Benjamin Israelow et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mutations Strengthened SARS-CoV-2 Infectivity

(2020) Jiahui Chen et al.   JOURNAL OF MOLECULAR BIOLOGY

Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial

(2020) Pedro M Folegatti et al.   LANCET

Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies

(2020) Alina Baum et al.   SCIENCE

Lung Expression of Human ACE2 Sensitizes the Mouse to SARS-CoV-2 Infection

(2020) Kun Han et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Animal models for COVID-19

(2020) César Muñoz-Fontela et al.   NATURE

Lung-targeting lentiviral vector for passive immunisation against influenza

(2020) Tiong Kit Tan et al.   THORAX

Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial

(2020) Maheshi N Ramasamy et al.   LANCET

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

(2020) Fernando P. Polack et al.   NEW ENGLAND JOURNAL OF MEDICINE

REGN-COV2, a Neutralizing Antibody Cocktail, in Outpatients with Covid-19

(2020) David M. Weinreich et al.   NEW ENGLAND JOURNAL OF MEDICINE

Adeno-associated virus vectored immunoprophylaxis to prevent HIV in healthy adults: a phase 1 randomised controlled trial

(2019) Frances H Priddy et al.   Lancet HIV

The murine lung as a factory to produce secreted intrapulmonary and circulatory proteins

(2018) Michael C. Paul-Smith et al.   GENE THERAPY

Intramuscular Adeno-Associated Virus–Mediated Expression of Monoclonal Antibodies Provides 100% Protection Against Ebola Virus Infection in Mice

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Emerging Issues in AAV-Mediated In Vivo Gene Therapy

(2018) Pasqualina Colella et al.   Molecular Therapy-Methods & Clinical Development

Adeno-associated virus gene delivery of broadly neutralizing antibodies as prevention and therapy against HIV-1

(2018) Allen Lin et al.   Retrovirology

Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis

(2016) Eric W F W Alton et al.   THORAX

Focused antibody response to influenza linked to antigenic drift

(2015) Kuan-Ying A. Huang et al.   JOURNAL OF CLINICAL INVESTIGATION

Vectored Expression of the Broadly Neutralizing Antibody FI6 in Mouse Airway Provides Partial Protection against a New Avian Influenza A Virus, H7N9

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Broad protection against influenza infection by vectored immunoprophylaxis in mice

(2013) Alejandro B Balazs et al.   NATURE BIOTECHNOLOGY

Intranasal Antibody Gene Transfer in Mice and Ferrets Elicits Broad Protection Against Pandemic Influenza

(2013) M. P. Limberis et al.   Science Translational Medicine

Antibody-based protection against HIV infection by vectored immunoprophylaxis

(2011) Alejandro B. Balazs et al.   NATURE

Analysis of AAV Serotypes 1–9 Mediated Gene Expression and Tropism in Mice After Systemic Injection

(2008) Carmela Zincarelli et al.   MOLECULAR THERAPY

Genetic delivery of an anti-RSV antibody to protect against pulmonary infection with RSV

(2008) Davor Skaricic et al.   VIROLOGY