Local extracellular matrix alignment directs cellular protrusion dynamics and migration through Rac1 and FAK

Comparative mechanisms of cancer cell migration through 3D matrix and physiological microtracks

(2015) Shawn P. Carey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Cell-mediated fibre recruitment drives extracellular matrix mechanosensing in engineered fibrillar microenvironments

(2015) Brendon M. Baker et al.   NATURE MATERIALS

Three-dimensional matrix fiber alignment modulates cell migration and MT1-MMP utility by spatially and temporally directing protrusions

(2015) Stephanie I. Fraley et al.   Scientific Reports

3D Collagen Alignment Limits Protrusions to Enhance Breast Cancer Cell Persistence

(2014) Kristin M. Riching et al.   BIOPHYSICAL JOURNAL

Mechanistic adaptability of cancer cells strongly affects anti-migratory drug efficacy

(2014) W. Sun et al.   Journal of the Royal Society Interface

Mechanotransduction of fluid stresses governs 3D cell migration

(2014) W. J. Polacheck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-dimensional cell migration does not follow a random walk

(2014) P.-H. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Leading malignant cells initiate collective epithelial cell invasion in a three-dimensional heterotypic tumor spheroid model

(2013) Shawn P. Carey et al.   CLINICAL & EXPERIMENTAL METASTASIS

Matrix Microarchitecture and Myosin II Determine Adhesion in 3D Matrices

(2013) Kristopher E. Kubow et al.   CURRENT BIOLOGY

Patterned Collagen Fibers Orient Branching Mammary Epithelium through Distinct Signaling Modules

(2013) Douglas G. Brownfield et al.   CURRENT BIOLOGY

Dimensions in cell migration

(2013) Andrew D Doyle et al.   CURRENT OPINION IN CELL BIOLOGY

Preclinical intravital microscopy of the tumour-stroma interface: invasion, metastasis, and therapy response

(2013) Stephanie Alexander et al.   CURRENT OPINION IN CELL BIOLOGY

Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

(2013) Katarina Wolf et al.   JOURNAL OF CELL BIOLOGY

Extracellular matrix determinants and the regulation of cancer cell invasion stratagems

(2013) A.L. WILLIS et al.   JOURNAL OF MICROSCOPY

Topographical guidance of 3D tumor cell migration at an interface of collagen densities

(2013) Francois Bordeleau et al.   PHYSICAL BIOLOGY

Rapid disorganization of mechanically interacting systems of mammary acini

(2013) Q. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of filopodia in the recognition of nanotopographies

(2013) Jörg Albuschies et al.   Scientific Reports

Biophysical control of invasive tumor cell behavior by extracellular matrix microarchitecture

(2012) Shawn P. Carey et al.   BIOMATERIALS

Force Fluctuations within Focal Adhesions Mediate ECM-Rigidity Sensing to Guide Directed Cell Migration

(2012) Sergey V. Plotnikov et al.   CELL

The extracellular matrix: A dynamic niche in cancer progression

(2012) Pengfei Lu et al.   JOURNAL OF CELL BIOLOGY

United we stand – integrating the actin cytoskeleton and cell–matrix adhesions in cellular mechanotransduction

(2012) Ulrich S. Schwarz et al.   JOURNAL OF CELL SCIENCE

The Outgrowth of Micrometastases Is Enabled by the Formation of Filopodium-like Protrusions

(2012) Tsukasa Shibue et al.   Cancer Discovery

Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma

(2011) Matthew W. Conklin et al.   AMERICAN JOURNAL OF PATHOLOGY

Mechanobiology of tumor invasion: Engineering meets oncology

(2011) Shawn P. Carey et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Intravital microscopy: new insights into metastasis of tumors

(2011) E. Beerling et al.   JOURNAL OF CELL SCIENCE

Microfluidic Generation of Haptotactic Gradients through 3D Collagen Gels for Enhanced Neurite Growth

(2011) Harini G. Sundararaghavan et al.   JOURNAL OF NEUROTRAUMA

Interstitial guidance of cancer invasion

(2011) Pavlo G. Gritsenko et al.   JOURNAL OF PATHOLOGY

Origins of regulated cell-to-cell variability

(2011) Berend Snijder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

(2010) Ana M. Pasapera et al.   JOURNAL OF CELL BIOLOGY

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Fibril Microstructure Affects Strain Transmission Within Collagen Extracellular Matrices

(2009) Blayne A. Roeder   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Plasticity of cell migration: a multiscale tuning model

(2009) Peter Friedl et al.   JOURNAL OF CELL BIOLOGY

Adhesion signaling - crosstalk between integrins, Src and Rho

(2009) S. Huveneers et al.   JOURNAL OF CELL SCIENCE

Coordination of Rho GTPase activities during cell protrusion

(2009) Matthias Machacek et al.   NATURE

Random versus directionally persistent cell migration

(2009) Ryan J. Petrie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK–ERK linkage

(2009) P P Provenzano et al.   ONCOGENE

Collagen-based cell migration models in vitro and in vivo

(2009) Katarina Wolf et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The Signaling Mechanisms Underlying Cell Polarity and Chemotaxis

(2009) F. Wang   Cold Spring Harbor Perspectives in Biology

Guiding cell migration in 3D: A collagen matrix with graded directional stiffness

(2009) Ektoras Hadjipanayi et al.   CELL MOTILITY AND THE CYTOSKELETON

Contact Guidance Mediated Three-Dimensional Cell Migration is Regulated by Rho/ROCK-Dependent Matrix Reorganization

(2008) Paolo P. Provenzano et al.   BIOPHYSICAL JOURNAL

Mapping Local Matrix Remodeling Induced by a Migrating Tumor Cell Using Three-Dimensional Multiple-Particle Tracking

(2008) Ryan J. Bloom et al.   BIOPHYSICAL JOURNAL

Crosstalk between small GTPases and polarity proteins in cell polarization

(2008) Sandra Iden et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Polarity proteins in migration and invasion

(2008) S Etienne-Manneville   ONCOGENE

Quantification of Cell Edge Velocities and Traction Forces Reveals Distinct Motility Modules during Cell Spreading

(2008) Benjamin J. Dubin-Thaler et al.   PLoS One

Lamellipodia nucleation by filopodia depends on integrin occupancy and downstream Rac1 signaling

(2007) Hervé Guillou et al.   EXPERIMENTAL CELL RESEARCH