DNA-encoded library versus RNA-encoded library selection enables design of an oncogenic noncoding RNA inhibitor

Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer

(2020) Matthew G. Costales et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Progress toward the development of the small molecule equivalent of small interfering RNA

(2020) Matthew D. Disney et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

MicroRNA-941 regulates the proliferation of breast cancer cells by altering histone H3 Ser 10 phosphorylation

(2020) Sunil Kumar Surapaneni et al.   Scientific Reports

Activity-Based DNA-Encoded Library Screening

(2019) Wesley G. Cochrane et al.   ACS Combinatorial Science

Perspectives on targeting RNA with small molecules to capture opportunities at the intersection of chemistry, biology, and medicine

(2019) Matthew D. Disney   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Novel Nucleic Acid Binding Small Molecules Discovered Using DNA-Encoded Chemistry

(2019) Litovchick et al.   MOLECULES

Off-DNA DNA-Encoded Library Affinity Screening

(2019) Amber L. Hackler et al.   ACS Combinatorial Science

DNA-Encoded Chemical Libraries: A Selection System Based on Endowing Organic Compounds with Amplifiable Information

(2018) Dario Neri et al.   Annual Review of Biochemistry

Second-generation DNA-templated macrocycle libraries for the discovery of bioactive small molecules

(2018) Dmitry L. Usanov et al.   Nature Chemistry

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Drugging the RNA World

(2018) Matthew D. Disney et al.   Cold Spring Harbor Perspectives in Biology

Poisson Statistics of Combinatorial Library Sampling Predict False Discovery Rates of Screening

(2017) Andrew B. MacConnell et al.   ACS Combinatorial Science

The Human Cell Atlas

(2017) Aviv Regev et al.   eLife

Defining RNA–Small Molecule Affinity Landscapes Enables Design of a Small Molecule Inhibitor of an Oncogenic Noncoding RNA

(2017) Sai Pradeep Velagapudi et al.   ACS Central Science

High-throughput Identification of DNA-Encoded IgG Ligands that Distinguish Active and Latent Mycobacterium tuberculosis Infections

(2016) Kimberly R. Mendes et al.   ACS Chemical Biology

Analysis of secondary structural elements in human microRNA hairpin precursors

(2016) Biao Liu et al.   BMC BIOINFORMATICS

B4GALT3 up-regulation by miR-27a contributes to the oncogenic activity in human cervical cancer cells

(2016) Yanrui Sun et al.   CANCER LETTERS

The protein phosphatase 4 - PEA15 axis regulates the survival of breast cancer cells

(2016) Hiba N. Mohammed et al.   CELLULAR SIGNALLING

Small Molecule-Based Pattern Recognition To Classify RNA Structure

(2016) Christopher S. Eubanks et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA-encoded chemistry: enabling the deeper sampling of chemical space

(2016) Robert A. Goodnow et al.   NATURE REVIEWS DRUG DISCOVERY

DiffLogo: a comparative visualization of sequence motifs

(2015) Martin Nettling et al.   BMC BIOINFORMATICS

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

DataWarrior: An Open-Source Program For Chemistry Aware Data Visualization And Analysis

(2015) Thomas Sander et al.   Journal of Chemical Information and Modeling

Ribosome profiling reveals the what, when, where and how of protein synthesis

(2015) Gloria A. Brar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

DNA-Encoded Solid-Phase Synthesis: Encoding Language Design and Complex Oligomer Library Synthesis

(2015) Andrew B. MacConnell et al.   ACS Combinatorial Science

Predicting effective microRNA target sites in mammalian mRNAs

(2015) Vikram Agarwal et al.   eLife

Small Targeted Cytotoxics: Current State and Promises from DNA-Encoded Chemical Libraries

(2013) Nikolaus Krall et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Androgen-regulated processing of the oncomir MiR-27a, which targets Prohibitin in prostate cancer

(2012) Claire E. Fletcher et al.   HUMAN MOLECULAR GENETICS

MiR-27 as a Prognostic Marker for Breast Cancer Progression and Patient Survival

(2012) Wei Tang et al.   PLoS One

Small-molecule discovery from DNA-encoded chemical libraries

(2011) Ralph E. Kleiner et al.   CHEMICAL SOCIETY REVIEWS

MicroRNA-155 Functions as an OncomiR in Breast Cancer by Targeting the Suppressor of Cytokine Signaling 1 Gene

(2010) S. Jiang et al.   CANCER RESEARCH

MicroRNA-27a Indirectly Regulates Estrogen Receptor α Expression and Hormone Responsiveness in MCF-7 Breast Cancer Cells

(2010) Xiangrong Li et al.   ENDOCRINOLOGY

Cooperative and individualistic functions of the microRNAs in the miR-23a~27a~24-2 cluster and its implication in human diseases

(2010) Ravindresh Chhabra et al.   Molecular Cancer

Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion

(2010) A N Santhanam et al.   ONCOGENE

Post-transcriptional regulation of miR-27 in murine cytomegalovirus infection

(2010) A. H. Buck et al.   RNA

Design, synthesis and selection of DNA-encoded small-molecule libraries

(2009) Matthew A Clark et al.   Nature Chemical Biology

Discovering ligands for a microRNA precursor with peptoid microarrays

(2009) Sara Chirayil et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

(2009) N. T. Ingolia et al.   SCIENCE

MicroRNA-21 targets tumor suppressor genes in invasion and metastasis

(2008) Shuomin Zhu et al.   CELL RESEARCH

Development of a Dual-Luciferase Reporter System for In Vivo Visualization of MicroRNA Biogenesis and Posttranscriptional Regulation

(2008) J. Y. Lee et al.   JOURNAL OF NUCLEAR MEDICINE

Two-Dimensional Combinatorial Screening Identifies Specific Aminoglycoside−RNA Internal Loop Partners

(2008) Matthew D. Disney et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY