Article
Plant Sciences
Hongbo Zhang, Tongtong Yao, Yue Wang, Jiechen Wang, Jiaqi Song, Congcong Cui, Guangxin Ji, Jianing Cao, Salman Muhammad, Hong Ao, Huihui Zhang
Summary: In this study, the effects of overexpression of CDSP32 on reactive oxygen species (ROS) metabolism in tobacco leaves exposed to cadmium (Cd) were investigated. The results showed that the number of differentially expressed proteins (DEPs) in plants overexpressing CDSP32 was lower compared to wild-type tobacco under Cd exposure, especially down-regulated DEPs. Cd exposure disrupted ROS metabolism in tobacco leaves. Although Cd exposure inhibited the activities of SOD, CAT, and APX and the expression of proteins related to the Trx-Prx pathway, the increase in the activities of POD, MDHAR, DHAR, GR, GPX, and GST played an important role in the physiological response to Cd exposure. Notably, overexpression of CDSP32 alleviated the decrease in SOD and CAT expression and activities caused by Cd exposure and enhanced the function of POD. CDSP32 increased the H2O2 scavenging capacity of the AsA-GSH cycle and Trx-Prx pathway under Cd exposure, especially regulating 2-Cys Prx protein expression and TPX activity. Therefore, overexpression of CDSP32 can mitigate oxidative damage in tobacco leaves under Cd exposure by modulating antioxidant defense systems.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Review
Biochemistry & Molecular Biology
Tina Oberacker, Leonie Kraft, Moritz Schanz, Joerg Latus, Severin Schricker
Summary: Thioredoxin-1 (Trx-1) is a multifunctional protein that plays a crucial role in maintaining cellular functions such as redox homeostasis, proliferation, and DNA synthesis. It also modulates transcription factors and regulates cell death, making it essential for proper cell and organ function. Dysregulation of Trx gene expression or activity can contribute to various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. This review highlights the importance of Trx in health and disease, as well as its potential as a biomarker.
Article
Environmental Sciences
Chudai Zeng, Zheng Huang, Wengui Tao, Langchao Yan, Dong Tang, Fenghua Chen, Shifu Li
Summary: This study genetically predicts the causal relationship between smoking and intracranial aneurysms (IA). The results show that smoking, especially regular smoking, is associated with a higher risk of IA. Additionally, higher blood levels of cotinine and cadmium are also associated with increased IA risk.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Cell Biology
Daren L. Knoell, Todd A. Wyatt
Summary: Cadmium, a toxic heavy metal primarily released through industrial processes, enters the food chain and adversely affects organs like the kidneys, bones, vasculature, and lungs. Despite extensive studies on cells and animal models, the impact of cadmium on human immune function remains poorly understood. More research is needed to understand how chronic exposure to cadmium negatively impacts human health.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
(2021)
Article
Environmental Sciences
Xiong Li, Di Chen, Boqun Li, Ya Yang, Yongping Yang
Summary: Cadmium pollution is a major environmental issue, and this study investigated the detoxification mechanisms in a Cd-hyperaccumulating turnip landrace exposed to different Cd treatments. Enriched pathways such as flavonoid biosynthesis, sulfur metabolism, and glucosinolate biosynthesis were found to play important roles in Cd detoxification, while protein pathways like glutathione metabolism were also crucial. This research provides insights into the molecular mechanisms of Cd tolerance in turnips and highlights potential pathways for developing plants with reduced Cd accumulation for food or phytoremediation purposes.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Environmental Sciences
Antonio Leon-Vaz, Luis C. Romero, Cecilia Gotor, Rosa Leon, Javier Vigara
Summary: This study investigated the effect of cadmium on the microalga Chlorella sorokiniana through a proteomic approach, revealing adjustments in various metabolic pathways and an increase in pathways such as photorespiration and antioxidant enzymes. Additionally, it was found that Chlorella sorokiniana exhibits high tolerance to cadmium exposure, suggesting its potential use in bioremediation processes.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Environmental Sciences
Yang Yang, Yanling Li, Tianqi Wang, Weiping Chen, Meie Wang, Yating Dai
Summary: The study found that high concentrations of potentially toxic elements accumulated in tobacco leaves, mainly sourced from soil contamination, posing health risks to local smokers and passive smokers. Industrial emissions and applied fertilizers were identified as major sources of PTEs, with dynamic interactions between soil factors affecting the uptake by plants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Biochemistry & Molecular Biology
Yilin Zheng, Mengyu Li, Binman Liu, Yafei Qin, Jinhua Li, Yu Pan, Xingguo Zhang
Summary: Phytochelatins (PCs) are low molecular-weight polypeptides in plants that can bind to metal ions and affect physiological metabolism. This study found that the expression of PCL in transgenic plants improves resistance to Cd and antioxidant abilities, but also leads to higher levels of Cd accumulation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biophysics
Renata Guimaraes de Sa, Tatiane Moraes Arantes, Erenilda Ferreira de Macedo, Luisa Molina Dona, Jeniffer C. F. Pereira, Carolina Ramos Hurtado, R. Jose Varghese, Oluwatobi Samuel Oluwafemi, Dayane Batista Tada
Summary: This study focused on the evaluation of the photoprotective activity and cytotoxicity of zirconia nanoparticles. The results showed that ZrO2 NPs exhibited low cytotoxicity and provided effective protection under UV irradiation.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Review
Environmental Sciences
Liangjie Niu, Chunyang Li, Wei Wang, Jinghua Zhang, Monica Scali, Weiqiang Li, Hui Liu, Fuju Tai, Xiuli Hu, Xiaolin Wu
Summary: In this review, proteomic studies on Cd-tolerance mechanisms in Cd-tolerant crops and Cdhyperaccumulating plants were summarized, especially focusing on the similarities and differences across plant species. Enhanced differentially abundant proteins identified through proteomic studies can be potential targets for developing Cd-hyperaccumulators and Cd-tolerant crops, which is crucial for ensuring food security for the growing global population. The article also discusses the methodological drawbacks in current proteomic studies and suggests the utilization of better protocols and advanced techniques to enhance the reliability and applicability of future Cd-stress-related studies in plants. This review provides insights into improving phytoremediation efficiency and studying the molecular mechanisms of Cd enrichment in plants.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Biology
Halil Erdem
Summary: The study found that application of biochar can reduce the uptake of cadmium by tobacco plants, with corn cob biochar showing more effectiveness in this aspect.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2021)
Article
Multidisciplinary Sciences
Carla Roselli, Ivan Fagiolino, Donatella Desideri, Davide Sisti, Maria Assunta Meli
Summary: Cigarette butts are known to contain toxic metals, and the leachability of these metals when exposed to aqueous solutions in the environment determines the potential threat to the environment and human health. This study aimed to determine the presence and mobility of toxic elements in cigarette butts, with results showing that different environmental conditions can affect the solubility of these elements.
Article
Otorhinolaryngology
Carla R. Schubert, A. Alex Pinto, Adam J. Paulsen, Karen J. Cruickshanks
Summary: The study aims to determine the 10-year cumulative incidence of olfactory impairment and evaluate modifiable risk factors, with findings suggesting that higher blood cadmium levels and tobacco smoke exposure may contribute to an increased risk of developing olfactory impairment.
JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY
(2021)
Article
Engineering, Environmental
Dazhong Zhang, Jiajia Liu, Yuanbo Zhang, Hairong Wang, Shuwei Wei, Xu Zhang, Ding Zhang, Haosen Ma, Qin Ding, Lingjian Ma
Summary: Soil cadmium (Cd) contamination poses a threat to food security and human health by reducing wheat yield and quality. In this study, the mechanisms of Cd tolerance were investigated using two wheat cultivars, Luomai23 (LM, Cd-sensitive) and Zhongyu10 (ZY, Cd-tolerant). Cd inhibited wheat growth, caused oxidative stress, affected carbon and nitrogen metabolism, and altered root exudates. ZY showed lower root Cd concentration by about 35%, reduced Cd uptake through root exudation, and enhanced Cd cell wall fixation and vacuolar compartmentalization. ZY also exhibited increased resilience to Cd due to enhanced antioxidant capacity, plasma membrane stability, nitrogen metabolism, and endoplasmic reticulum homeostasis.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Plant Sciences
Nicole P. Porto, Raissa S. C. Bret, Paulo V. L. Souza, Silvio A. Candido-Sobrinho, David B. Medeiros, Alisdair R. Fernie, Danilo M. Daloso
Summary: The study found that TRX o1 restricts the carbon flux from glycolysis and TCAC to glutamine under light conditions. In contrast to the wild type, mutants exhibited significant changes in TCAC metabolite content and 13C enrichment under both dark and light conditions.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2022)
Article
Plant Sciences
Wanli You, Jinglin Zhang, Xueyin Ru, Feng Xu, Zhengguo Wu, Peng Jin, Yonghua Zheng, Shifeng Cao
Summary: This study investigated the effect of calcium chloride (CaCl2) treatment on GABA accumulation in fresh-cut cantaloupe and the underlying mechanisms. The results showed that CaCl2 treatment increased GABA content and the activities of GAD and SSADH enzymes, while reducing glutamate content and GABA-T activity. Additionally, CaCl2 treatment upregulated the expressions of CmCML11 and CmCAMTA5, as well as several GABA shunt genes, through the transcriptional activation by CmCAMTA5. Furthermore, the interaction between CmCML11 and CmCAMTA5 enhanced the transcriptional activation of GABA shunt genes. Overall, this study reveals that CaCl2 treatment promotes GABA accumulation in fresh-cut cantaloupe through the combined effect of CmCML11 and CmCAMTA5 in regulating the expressions of GABA shunt genes.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
Min Wang, Yupeng Wang, Xiaohui Wang, Guangwei Wei, Huiyi Yang, Xi Yang, Tinghai Shen, Huijie Qu, Sheng Fang, Ziming Wu
Summary: This study identified the high nitrogen use efficiency (NUE) black sesame variety 17-156 and analyzed its underlying physiological and molecular mechanisms. The results showed that 17-156 possesses a sophisticated nitrogen metabolizing machinery to uptake and assimilate higher quantities of inorganic nitrogen, simultaneously improving carbon metabolism and growth. Many important genes were up-regulated in 17-156 under high nitrogen condition. Additionally, 38 potential candidate genes were identified for future studies to improve sesame's NUE. These findings provide valuable resources for understanding the regulatory network of nitrogen metabolism and developing sesame cultivars with improved NUE.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
He Dong, Chongmei Xu, Chengtao Zhang, Li Zhang, Yaqin Yao, Suiqi Zhang
Summary: The study found that short cells in maize leaves not only improve leaf mechanical support and photosynthetic performance, enhance drought resistance, but also participate in stomatal regulation.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
Na Liu, Wenyan Shang, Mengxin Guan, Jibin Xiao, Guangxiang Tian, Baozhan Ma, Wenjing Shang, Xu Li, Shijia Zhao, Chuang Li, Kun Cheng, Wenming Zheng
Summary: This study cloned the full-length cDNA sequence of TaSPX3 gene in wheat and found that TaSPX3 responds to low phosphorus stress in multiple wheat genotypes. Overexpressing TaSPX3 can alleviate phosphorus deficiency symptoms and promote plant growth in Arabidopsis. The study also revealed the interaction of TaSPX3 with other genes related to the phosphorus starvation signaling pathway.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
Kongyuan Wu, Lizhen Wang, Zihan Wu, Ziqing Liu, Zengfei Li, Jun Shen, Shengjie Shi, Hong Liu, Christopher Rensing, Renwei Feng
Summary: Selenium (Se) can reduce uptake and translocation of cadmium (Cd) in plants by regulating root morphology. This study investigated the effects of Se(IV) on root exudates, root morphology, root endogenous hormones, and Cd uptake efficiency in rice under Cd stress. The results showed that Se(IV) significantly reduced Cd concentrations in shoots and roots, and decreased Cd uptake efficiency via root hairs. Se(IV) also affected root morphology, root exudates, and the synthesis of hormones like IAA and JA. However, transcriptome analysis revealed no upregulated differentially expressed genes (DEGs) in IAA synthesis.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
Di Wang, Huaifang Zhang, Xuefei Hu, Haizhen Zhang, Shuang Feng, Aimin Zhou
Summary: This study identified a cell number regulator gene called SlCNR8 in willow, which enhances resistance to trace metals in transgenic poplar seedlings. SlCNR8 reduces Cd uptake and accumulation, and can be used as a candidate gene for genetic improvement of phytostabilisation of trace metals.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)