Centipeda minima extract sensitizes lung cancer cells to DNA-crosslinking agents via targeting Fanconi anemia pathway

Anti-cancer Activity of Centipeda minima Extract in Triple Negative Breast Cancer via Inhibition of AKT, NF-κB, and STAT3 Signaling Pathways

(2020) Magnolia Muk-Lan Lee et al.   Frontiers in Oncology

Medicinal Plant Centipeda Minima: A Resource of Bioactive Compounds

(2020) Nguyen Thi Thuy Linh et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

FANCD2 Confers a Malignant Phenotype in Esophageal Squamous Cell Carcinoma by Regulating Cell Cycle Progression

(2020) Lisa Chan Lei et al.   Cancers

Protection against chemotherapy- and radiotherapy-induced side effects: A review based on the mechanisms and therapeutic opportunities of phytochemicals

(2020) Yong-Qiang Liu et al.   PHYTOMEDICINE

The Fanconi Anemia Pathway and Fertility

(2019) Vanessa Tsui et al.   TRENDS IN GENETICS

DNA Repair: Translation to the Clinic

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Traditional Chinese Medicine Preparation Combined Therapy May Improve Chemotherapy Efficacy: A Systematic Review and Meta-Analysis

(2019) Jiaming Wu et al.   Evidence-based Complementary and Alternative Medicine

Centipeda minima extract exerts antineuroinflammatory effects via the inhibition of NF-κB signaling pathway

(2019) Si-Yi Li et al.   PHYTOMEDICINE

Celastrol-induced degradation of FANCD2 sensitizes pediatric high-grade gliomas to the DNA-crosslinking agent carboplatin

(2019) Dennis S. Metselaar et al.   EBioMedicine

Sensitization of tumor cells to chemotherapy by natural products: A systematic review of preclinical data and molecular mechanisms

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Replication stress induces accumulation of FANCD2 at central region of large fragile genes

(2018) Yusuke Okamoto et al.   NUCLEIC ACIDS RESEARCH

Tamoxifen-resistant breast cancer cells are resistant to DNA-damaging chemotherapy because of upregulated BARD1 and BRCA1

(2018) Yinghua Zhu et al.   Nature Communications

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Mechanism of Ubiquitination and Deubiquitination in the Fanconi Anemia Pathway

(2017) Sylvie van Twest et al.   MOLECULAR CELL

Suppression of the FA pathway combined with CHK1 inhibitor hypersensitize lung cancer cells to gemcitabine

(2017) Chun-Hua Dai et al.   Scientific Reports

Cisplatin in the modern era: The backbone of first-line chemotherapy for non-small cell lung cancer

(2016) D.A. Fennell et al.   CANCER TREATMENT REVIEWS

Cellular response to DNA interstrand crosslinks: the Fanconi anemia pathway

(2016) David Lopez-Martinez et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

DNA damage repair and tolerance: a role in chemotherapeutic drug resistance

(2016) M. R. Salehan et al.   BRITISH JOURNAL OF BIOMEDICAL SCIENCE

Celastrol induces proteasomal degradation of FANCD2 to sensitize lung cancer cells to DNA crosslinking agents

(2015) Gui-Zhen Wang et al.   CANCER SCIENCE

Skp1 in lung cancer: clinical significance and therapeutic efficacy of its small molecule inhibitors

(2015) Yong-Qiang Liu et al.   Oncotarget

Traditional Chinese Medicine: A Treasured Natural Resource of Anticancer Drug Research and Development

(2014) Chao-Yun Wang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Cytotoxic activity of two natural sesquiterpene lactones, isobutyroylplenolin and arnicolide D, on human colon cancer cell line HT-29

(2014) Xuedan Huang et al.   NATURAL PRODUCT RESEARCH

Curcumin reverses cisplatin resistance in cisplatin-resistant lung caner cells by inhibiting FA/BRCA pathway

(2014) Ping Chen et al.   TUMOR BIOLOGY

Fanconi Anemia Repair Pathway Dysfunction, a Potential Therapeutic Target in Lung Cancer

(2014) Wenrui Duan et al.   Frontiers in Oncology

Regulation of FANCD2 by the mTOR Pathway Contributes to the Resistance of Cancer Cells to DNA Double-Strand Breaks

(2013) C. Shen et al.   CANCER RESEARCH

Small Compound 6-O-Angeloylplenolin Induces Mitotic Arrest and Exhibits Therapeutic Potentials in Multiple Myeloma

(2011) Ying Liu et al.   PLoS One

FANCD2 Hurdles the DNA Interstrand Crosslink

(2009) George-Lucian Moldovan et al.   CELL

CHK1 inhibition as a strategy for targeting fanconi anemia (FA) DNA repair pathway deficient tumors

(2009) Clark C Chen et al.   Molecular Cancer

2β-(Isobutyryloxy)florilenalin, a Sesquiterpene Lactone Isolated from the Medicinal Plant Centipeda minima, Induces Apoptosis in Human Nasopharyngeal Carcinoma CNE Cells

(2009) Miaoxian Su et al.   MOLECULES