Individual differences in orexin-I receptor modulation of motivation for the opioid remifentanil

Orexin-1 receptor signaling increases motivation for cocaine-associated cues

(2015) Brandon S. Bentzley et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The dark side of emotion: The addiction perspective

(2015) George F. Koob   EUROPEAN JOURNAL OF PHARMACOLOGY

Hypocretin/Orexin Regulation of Dopamine Signaling and Cocaine Self-Administration Is Mediated Predominantly by Hypocretin Receptor 1

(2014) Courtney D. Prince et al.   ACS Chemical Neuroscience

Orexin/hypocretin role in reward: implications for opioid and other addictions

(2014) Corey Baimel et al.   BRITISH JOURNAL OF PHARMACOLOGY

Rapid dopamine transmission within the nucleus accumbens: Dramatic difference between morphine and oxycodone delivery

(2014) Caitlin M. Vander Weele et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Designer receptors show role for ventral pallidum input to ventral tegmental area in cocaine seeking

(2014) Stephen V Mahler et al.   NATURE NEUROSCIENCE

Motivational activation: a unifying hypothesis of orexin/hypocretin function

(2014) Stephen V Mahler et al.   NATURE NEUROSCIENCE

Individual Variation in the Motivational and Neurobiological Effects of an Opioid Cue

(2014) Lindsay M Yager et al.   NEUROPSYCHOPHARMACOLOGY

Economic demand predicts addiction-like behavior and therapeutic efficacy of oxytocin in the rat

(2014) B. S. Bentzley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypocretin (orexin) facilitates reward by attenuating the antireward effects of its cotransmitter dynorphin in ventral tegmental area

(2014) J. W. Muschamp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The paraventricular nucleus of the thalamus is recruited by both natural rewards and drugs of abuse: recent evidence of a pivotal role for orexin/hypocretin signaling in this thalamic nucleus in drug-seeking behavior

(2014) Alessandra Matzeu et al.   Frontiers in Behavioral Neuroscience

Orexin / hypocretin 1 receptor antagonist reduces heroin self-administration and cue-induced heroin seeking

(2012) Rachel J. Smith et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The behavioral economics of drug self-administration: A review and new analytical approach for within-session procedures

(2012) Brandon S. Bentzley et al.   PSYCHOPHARMACOLOGY

Individual differences in rhesus monkeys' demand for drugs of abuse

(2011) Mikhail N. Koffarnus et al.   ADDICTION BIOLOGY

Effects of Daily Morphine Administration and Deprivation on Choice and Demand for Remifentanil and Cocaine in Rhesus Monkeys

(2011) Tammy Wade-Galuska et al.   JOURNAL OF THE EXPERIMENTAL ANALYSIS OF BEHAVIOR

Opiate versus psychostimulant addiction: the differences do matter

(2011) Aldo Badiani et al.   NATURE REVIEWS NEUROSCIENCE

Cocaine must enter the brain to evoke unconditioned dopamine release within the nucleus accumbens shell

(2011) Kirsten A. Porter-Stransky et al.   NEUROSCIENCE LETTERS

Intranasal Self-Administration of Remifentanil as the Foray into Opioid Abuse by an Anesthesia Resident

(2010) Adam I. Levine et al.   ANESTHESIA AND ANALGESIA

Self-administration of cocaine and remifentanil by monkeys: choice between single drugs and mixtures

(2010) Kevin B. Freeman et al.   PSYCHOPHARMACOLOGY

A novel IV cocaine self-administration procedure in rats: differential effects of dopamine, serotonin, and GABA drug pre-treatments on cocaine consumption and maximal price paid

(2010) Erik B. Oleson et al.   PSYCHOPHARMACOLOGY

Orexin-1 receptor antagonism decreases ethanol consumption and preference selectively in high-ethanol–preferring Sprague–Dawley rats

(2009) David E. Moorman et al.   ALCOHOL

Ambience and Drug Choice: Cocaine- and Heroin-Taking as a Function of Environmental Context in Humans and Rats

(2009) Daniele Caprioli et al.   BIOLOGICAL PSYCHIATRY

Lateral hypothalamic orexin/hypocretin neurons: A role in reward-seeking and addiction

(2009) Gary Aston-Jones et al.   BRAIN RESEARCH

Orexin/hypocretin signaling at the orexin 1 receptor regulates cue-elicited cocaine-seeking

(2009) Rachel J. Smith et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The hypocretin-orexin system regulates cocaine self-administration via actions on the mesolimbic dopamine system

(2009) Rodrigo A. España et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Orexin A/Hypocretin-1 Selectively Promotes Motivation for Positive Reinforcers

(2009) S. L. Borgland et al.   JOURNAL OF NEUROSCIENCE

Drug context differently regulates cocaine versus heroin self-administration and cocaine- versus heroin-induced Fos mRNA expression in the rat

(2009) Michele Celentano et al.   PSYCHOPHARMACOLOGY

Preferential Enhancement of Dopamine Transmission within the Nucleus Accumbens Shell by Cocaine Is Attributable to a Direct Increase in Phasic Dopamine Release Events

(2008) B. J. Aragona et al.   JOURNAL OF NEUROSCIENCE

 -Opioid Receptor-Mediated Depression of the Hypothalamic Hypocretin/Orexin Arousal System

(2008) Y. Li et al.   JOURNAL OF NEUROSCIENCE

Morphine Deprivation Increases Self-Administration of the Fast- and Short-Acting  -Opioid Receptor Agonist Remifentanil in the Rat

(2008) Z. D. Cooper et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Effects of cocaine place conditioning, chronic escalating-dose “binge” pattern cocaine administration and acute withdrawal on orexin/hypocretin and preprodynorphin gene expressions in lateral hypothalamus of Fischer and Sprague–Dawley rats

(2008) Y. Zhou et al.   NEUROSCIENCE

Economic demand and essential value.

(2008) Steven R. Hursh et al.   PSYCHOLOGICAL REVIEW

Opposite environmental regulation of heroin and amphetamine self-administration in the rat

(2008) Daniele Caprioli et al.   PSYCHOPHARMACOLOGY

Orexin neuronal circuitry: Role in the regulation of sleep and wakefulness

(2007) Kousaku Ohno et al.   FRONTIERS IN NEUROENDOCRINOLOGY