Manufacturing Process Development for Belzutifan, Part 4: Nitrogen Flow Criticality for Transfer Hydrogenation Control
出版年份 2021 全文链接
标题
Manufacturing Process Development for Belzutifan, Part 4: Nitrogen Flow Criticality for Transfer Hydrogenation Control
作者
关键词
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出版物
ORGANIC PROCESS RESEARCH & DEVELOPMENT
Volume -, Issue -, Pages -
出版商
American Chemical Society (ACS)
发表日期
2021-11-11
DOI
10.1021/acs.oprd.1c00231
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- (2021) Michael Pirnot et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
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- (2020) Toni K. Choueiri et al. NATURE MEDICINE
- An open-label phase II study to evaluate PT2977 for the treatment of von Hippel-Lindau disease-associated renal cell carcinoma.
- (2019) Eric Jonasch et al. JOURNAL OF CLINICAL ONCOLOGY
- 3-[(1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl]oxy-5-fluorobenzonitrile (PT2977), a Hypoxia-Inducible Factor 2α (HIF-2α) Inhibitor for the Treatment of Clear Cell Renal Cell Carcinoma
- (2019) Rui Xu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Allosteric inhibition of HIF-2α as a novel therapy for clear cell renal cell carcinoma
- (2019) Yancheng Yu et al. DRUG DISCOVERY TODAY
- Hazardous properties of hydrogen and hydrogen containing fuel gases
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- The role of hypoxia-inducible factor-2 alpha in angiogenesis
- (2018) Christina Befani et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Hypoxia-Inducible Factor 2-Dependent Pathways Driving Von Hippel–Lindau-Deficient Renal Cancer
- (2018) Florinda Meléndez-Rodríguez et al. Frontiers in Oncology
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- NMR Chemical Shifts of Trace Impurities: Common Laboratory Solvents, Organics, and Gases in Deuterated Solvents Relevant to the Organometallic Chemist
- (2010) Gregory R. Fulmer et al. ORGANOMETALLICS
- Scalable Reactor Design for Pharmaceuticals and Fine Chemicals Production. 3. A Novel Gas−Liquid Reactor for Catalytic Asymmetric Transfer Hydrogenation with Simultaneous Acetone Stripping
- (2008) Xiuyan Sun et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
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