RING-finger protein 6 promotes colorectal tumorigenesis by transcriptionally activating SF3B2

Colorectal cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

SF3B2-mediated RNA splicing drives human prostate cancer progression

(2019) Norihiko Kawamura et al.   CANCER RESEARCH

RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination

(2019) Ying Ren et al.   ACTA PHARMACOLOGICA SINICA

RNF6 Promotes Colorectal Cancer by Activating the Wnt/β-Catenin Pathway via Ubiquitination of TLE3

(2018) Lei Liu et al.   CANCER RESEARCH

RNF6 facilitates metastasis and radioresistance in hepatocellular carcinoma through ubiquitination of FoxA1

(2018) Jing Cai et al.   EXPERIMENTAL CELL RESEARCH

The Ring Finger Protein RNF6 Induces Leukemia Cell Proliferation as a Direct Target of Pre-B-cell Leukemia Homeobox 1

(2016) Xin Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Architecture of SF3b and Structural Consequences of Its Cancer-Related Mutations

(2016) Constantin Cretu et al.   MOLECULAR CELL

Increased expression ofSolute carrier family 12 member 5via gene amplification contributes to tumour progression and metastasis and associates with poor survival in colorectal cancer

(2015) Lixia Xu et al.   GUT

Dual Roles of RNF2 in Melanoma Progression

(2015) K. Rai et al.   Cancer Discovery

High antitumor activity of pladienolide B and its derivative in gastric cancer

(2013) Momoko Sato et al.   CANCER SCIENCE

Test-Firing Ammunition for Spliceosome Inhibition in Cancer

(2013) S. M. Dehm   CLINICAL CANCER RESEARCH

Phase I Pharmacokinetic and Pharmacodynamic Study of the First-in-Class Spliceosome Inhibitor E7107 in Patients with Advanced Solid Tumors

(2013) F. A. L. M. Eskens et al.   CLINICAL CANCER RESEARCH

A phase I, open-label, single-arm, dose-escalation study of E7107, a precursor messenger ribonucleic acid (pre-mRNA) splicesome inhibitor administered intravenously on days 1 and 8 every 21 days to patients with solid tumors

(2013) D. S. Hong et al.   INVESTIGATIONAL NEW DRUGS

Emerging patterns of somatic mutations in cancer

(2013) Ian R. Watson et al.   NATURE REVIEWS GENETICS

Molecular Genetics of Colorectal Cancer

(2011) Eric R. Fearon   Annual Review of Pathology-Mechanisms of Disease

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

Regulation of Androgen Receptor Transcriptional Activity and Specificity by RNF6-Induced Ubiquitination

(2009) Kexin Xu et al.   CANCER CELL