An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury

CNS fibroblasts form a fibrotic scar in response to immune cell infiltration

(2021) Cayce E. Dorrier et al.   NATURE NEUROSCIENCE

The emergence of transcriptional identity in somatosensory neurons

(2020) Nikhil Sharma et al.   NATURE

Microglia and macrophages promote corralling, wound compaction and recovery after spinal cord injury via Plexin-B2

(2020) Xiang Zhou et al.   NATURE NEUROSCIENCE

Synaptic Specificity, Recognition Molecules, and Assembly of Neural Circuits

(2020) Joshua R. Sanes et al.   CELL

Structure and flexibility in cortical representations of odour space

(2020) Stan L. Pashkovski et al.   NATURE

Tetanus insensitive VAMP2 differentially restores synaptic and dense core vesicle fusion in tetanus neurotoxin treated neurons

(2020) Rein I. Hoogstraaten et al.   Scientific Reports

Microglia-organized scar-free spinal cord repair in neonatal mice

(2020) Yi Li et al.   NATURE

Transcriptional Reprogramming of Distinct Peripheral Sensory Neuron Subtypes after Axonal Injury

(2020) William Renthal et al.   NEURON

Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates

(2020) Louis Faure et al.   Nature Communications

Chronic neuronal activation increases dynamic microtubules to enhance functional axon regeneration after dorsal root crush injury

(2020) Di Wu et al.   Nature Communications

Axonal branch patterning and neuronal shape diversity: roles in developmental circuit assembly

(2020) Ann-Kristin Hoersting et al.   CURRENT OPINION IN NEUROBIOLOGY

A Longitudinal Study of the Neurologic Safety of Acute Baclofen Use After Spinal Cord Injury

(2019) Jacquelyn J. Cragg et al.   Neurotherapeutics

High-resolution 3D imaging and analysis of axon regeneration in unsectioned spinal cord with or without tissue clearing

(2019) Brett J. Hilton et al.   Nature Protocols

Cbp-dependent histone acetylation mediates axon regeneration induced by environmental enrichment in rodent spinal cord injury models

(2019) Thomas H. Hutson et al.   Science Translational Medicine

Spinal cord repair: advances in biology and technology

(2019) Grégoire Courtine et al.   NATURE MEDICINE

SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

(2019) Frank Koopmans et al.   NEURON

The Struggle to Make CNS Axons Regenerate: Why Has It Been so Difficult?

(2019) James W. Fawcett   NEUROCHEMICAL RESEARCH

ADF/Cofilin-Mediated Actin Turnover Promotes Axon Regeneration in the Adult CNS

(2019) Andrea Tedeschi et al.   NEURON

Epigenomic signatures underpin the axonal regenerative ability of dorsal root ganglia sensory neurons

(2019) Ilaria Palmisano et al.   NATURE NEUROSCIENCE

Moving beyond the glial scar for spinal cord repair

(2019) Elizabeth J. Bradbury et al.   Nature Communications

The RAB3-RIM Pathway Is Essential for the Release of Neuromodulators

(2019) Claudia M. Persoon et al.   NEURON

Intrinsic mechanisms of neuronal axon regeneration

(2018) Marcus Mahar et al.   NATURE REVIEWS NEUROSCIENCE

The Biology of Regeneration Failure and Success After Spinal Cord Injury

(2018) Amanda Phuong Tran et al.   PHYSIOLOGICAL REVIEWS

Improved identification of concordant and discordant gene expression signatures using an updated rank-rank hypergeometric overlap approach

(2018) Kelly M. Cahill et al.   Scientific Reports

Intrinsic Determinants of Axon Regeneration

(2018) James W. Fawcett et al.   Developmental Neurobiology

Towards an Understanding of Synapse Formation

(2018) Thomas C. Südhof   NEURON

Cell biology of spinal cord injury and repair

(2017) Timothy M. O’Shea et al.   JOURNAL OF CLINICAL INVESTIGATION

A C1-C2 Module in Munc13 Inhibits Calcium-Dependent Neurotransmitter Release

(2017) Francesco Michelassi et al.   NEURON

Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release

(2017) Albrecht Sigler et al.   NEURON

A Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal Growth Program

(2016) Vijayendran Chandran et al.   NEURON

The Calcium Channel Subunit Alpha2delta2 Suppresses Axon Regeneration in the Adult CNS

(2016) Andrea Tedeschi et al.   NEURON

Intrinsic Control of Axon Regeneration

(2016) Zhigang He et al.   NEURON

DREADDs for Neuroscientists

(2016) Bryan L. Roth   NEURON

Brief Electrical Stimulation Accelerates Axon Regeneration in the Peripheral Nervous System and Promotes Sensory Axon Regeneration in the Central Nervous System

(2016) Tessa Gordon et al.   MOTOR CONTROL

A Surviving Intact Branch Stabilizes Remaining Axon Architecture after Injury as Revealed by In Vivo Imaging in the Mouse Spinal Cord

(2015) Ariana O. Lorenzana et al.   NEURON

The active-zone protein Munc13 controls the use-dependence of presynaptic voltage-gated calcium channels

(2015) Nathaniel Calloway et al.   eLife

Nogo limits neural plasticity and recovery from injury

(2014) Martin E Schwab et al.   CURRENT OPINION IN NEUROBIOLOGY

Functional regeneration beyond the glial scar

(2014) Jared M. Cregg et al.   EXPERIMENTAL NEUROLOGY

Entrapment via Synaptic-Like Connections between NG2 Proteoglycan+ Cells and Dystrophic Axons in the Lesion Plays a Role in Regeneration Failure after Spinal Cord Injury

(2014) Angela R. Filous et al.   JOURNAL OF NEUROSCIENCE

Restoring function after spinal cord injury: towards clinical translation of experimental strategies

(2014) Leanne M Ramer et al.   LANCET NEUROLOGY

Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing

(2014) Dmitry Usoskin et al.   NATURE NEUROSCIENCE

The Morphological and Molecular Nature of Synaptic Vesicle Priming at Presynaptic Active Zones

(2014) Cordelia Imig et al.   NEURON

Asynchronous therapy restores motor control by rewiring of the rat corticospinal tract after stroke

(2014) A. S. Wahl et al.   SCIENCE

Dynamic Control of Synaptic Vesicle Replenishment and Short-Term Plasticity by Ca2+-Calmodulin-Munc13-1 Signaling

(2013) Noa Lipstein et al.   NEURON

Long-Distance Growth and Connectivity of Neural Stem Cells after Severe Spinal Cord Injury

(2012) Paul Lu et al.   CELL

Munc13 controls the location and efficiency of dense-core vesicle release in neurons

(2012) Rhea van de Bospoort et al.   JOURNAL OF CELL BIOLOGY

Relevance of Exocytotic Glutamate Release from Retinal Glia

(2012) Michal Slezak et al.   NEURON

ADF/Cofilin-Mediated Actin Retrograde Flow Directs Neurite Formation in the Developing Brain

(2012) Kevin C. Flynn et al.   NEURON

The Presynaptic Active Zone

(2012) Thomas C. Südhof   NEURON

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Kruppel-like Factor 7 engineered for transcriptional activation promotes axon regeneration in the adult corticospinal tract

(2012) M. G. Blackmore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesis and Biological Evaluation of a Selective N- and P/Q-Type Calcium Channel Agonist

(2012) Mary Liang et al.   ACS Medicinal Chemistry Letters

Simple Neurite Tracer: open source software for reconstruction, visualization and analysis of neuronal processes

(2011) M. H. Longair et al.   BIOINFORMATICS

RIM Proteins Tether Ca2+ Channels to Presynaptic Active Zones via a Direct PDZ-Domain Interaction

(2011) Pascal S. Kaeser et al.   CELL

Rehabilitative training and plasticity following spinal cord injury

(2011) K. Fouad et al.   EXPERIMENTAL NEUROLOGY

In Vivo Imaging of Dorsal Root Regeneration: Rapid Immobilization and Presynaptic Differentiation at the CNS/PNS Border

(2011) A. Di Maio et al.   JOURNAL OF NEUROSCIENCE

Membrane trafficking events underlying axon repair, growth, and regeneration

(2011) Ona E. Bloom et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

RIM Determines Ca2+ Channel Density and Vesicle Docking at the Presynaptic Active Zone

(2011) Yunyun Han et al.   NEURON

In vivo imaging reveals a phase-specific role of STAT3 during central and peripheral nervous system axon regeneration

(2011) F. M. Bareyre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Munc18 and Munc13 regulate early neurite outgrowth

(2010) Jurjen H.P. Broeke et al.   BIOLOGY OF THE CELL

Electrical Activity Suppresses Axon Growth through Cav1.2 Channels in Adult Primary Sensory Neurons

(2010) Joana Enes et al.   CURRENT BIOLOGY

PTEN deletion enhances the regenerative ability of adult corticospinal neurons

(2010) Kai Liu et al.   NATURE NEUROSCIENCE

Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis

(2010) Ok-Ho Shin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Rank–rank hypergeometric overlap: identification of statistically significant overlap between gene-expression signatures

(2010) Seema B. Plaisier et al.   NUCLEIC ACIDS RESEARCH

Fusogenic Pairings of Vesicle-Associated Membrane Proteins (VAMPs) and Plasma Membrane t-SNAREs – VAMP5 as the Exception

(2010) Nazarul Hasan et al.   PLoS One

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

Red fluorescent Xenopus laevis: a new tool for grafting analysis

(2009) Christoph Waldner et al.   BMC DEVELOPMENTAL BIOLOGY

Chronically CNS-Injured Adult Sensory Neurons Gain Regenerative Competence upon a Lesion of Their Peripheral Axon

(2009) Bhavna Ylera et al.   CURRENT BIOLOGY

A common molecular basis for membrane docking and functional priming of synaptic vesicles

(2009) Léa Siksou et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

RIM1  and RIM1  Are Synthesized from Distinct Promoters of the RIM1 Gene to Mediate Differential But Overlapping Synaptic Functions

(2008) P. S. Kaeser et al.   JOURNAL OF NEUROSCIENCE

Functional Parameters of Voltage-Activated Ca2+ Currents From Olfactory Interneurons in the Antennal Lobe of Periplaneta americana

(2007) Andreas Husch et al.   JOURNAL OF NEUROPHYSIOLOGY