Mitochondrial DNA Copy Number as a Marker and Mediator of Stroke Prognosis

Mitochondria: Novel Mechanisms and Therapeutic Targets for Secondary Brain Injury After Intracerebral Hemorrhage

(2021) Weixiang Chen et al.   Frontiers in Aging Neuroscience

Biallelic variants in LIG3 cause a novel mitochondrial neurogastrointestinal encephalomyopathy

(2021) Elena Bonora et al.   BRAIN

Computationally efficient whole-genome regression for quantitative and binary traits

(2021) Joelle Mbatchou et al.   NATURE GENETICS

Mitochondrial DNA copy number is associated with all‐cause mortality and cardiovascular events in patients with peripheral arterial disease

(2020) A. Koller et al.   JOURNAL OF INTERNAL MEDICINE

Multilevel omics for the discovery of biomarkers and therapeutic targets for stroke

(2020) Joan Montaner et al.   Nature Reviews Neurology

Restoration of L-OPA1 alleviates acute ischemic stroke injury in rats via inhibiting neuronal apoptosis and preserving mitochondrial function

(2020) Yongxing Lai et al.   Redox Biology

Thinking outside the nucleus: Mitochondrial DNA copy number in health and disease

(2020) Christina A. Castellani et al.   MITOCHONDRION

The Polygenic and Monogenic Basis of Blood Traits and Diseases

(2020) Dragana Vuckovic et al.   CELL

Genome-wide association meta-analysis of functional outcome after ischemic stroke

(2019) Martin Söderholm et al.   NEUROLOGY

Mitochondrial DNA copy number is associated with mortality and infections in a large cohort of patients with chronic kidney disease.

(2019) Federica Fazzini; et al.   KIDNEY INTERNATIONAL

Adjustment for index event bias in genome-wide association studies of subsequent events

(2019) Frank Dudbridge et al.   Nature Communications

Variations in common diseases, hospital admissions, and deaths in middle-aged adults in 21 countries from five continents (PURE): a prospective cohort study

(2019) Gilles R Dagenais et al.   LANCET

Homozygous R627W mutations in POLG cause mitochondrial DNA depletion leading to encephalopathy, seizures and stroke-like episodes

(2019) Arumugam Paramasivam et al.   MITOCHONDRION

Mendelian Randomization—A Journey From Obscurity to Center Stage With a Few Potholes Along the Way

(2019) Sara Bandres-Ciga et al.   JAMA Neurology

Genome-Wide Association Study of White Blood Cell Counts in Patients With Ischemic Stroke

(2019) Nuria P. Torres-Aguila et al.   STROKE

mtDNA Copy Number Contributes to All-Cause Mortality of Lacunar Infarct in a Chinese Prospective Stroke Population

(2019) Li Song et al.   Journal of Cardiovascular Translational Research

Practice patterns and outcomes after stroke across countries at different economic levels (INTERSTROKE): an international observational study

(2018) Peter Langhorne et al.   LANCET

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

(2018) Marie Verbanck et al.   NATURE GENETICS

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

(2018) Rainer Malik et al.   NATURE GENETICS

Brief Reports: Protective Effects of Endothelial Progenitor Cell-Derived Extracellular Mitochondria in Brain Endothelium

(2018) Kazuhide Hayakawa et al.   STEM CELLS

Cerebrovascular Disease Knowledge Portal

(2018) Katherine M. Crawford et al.   STROKE

The MR-Base platform supports systematic causal inference across the human phenome

(2018) Gibran Hemani et al.   eLife

Plasmid-normalized quantification of relative mitochondrial DNA copy number

(2018) Federica Fazzini et al.   Scientific Reports

Mitochondria in Ischemic Stroke: New Insight and Implications

(2018) Fan Liu et al.   Aging and Disease

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019

(2018) Annalisa Buniello et al.   NUCLEIC ACIDS RESEARCH

Association between mitochondrial DNA copy number and sudden cardiac death: findings from the Atherosclerosis Risk in Communities study (ARIC)

(2017) Yiyi Zhang et al.   EUROPEAN HEART JOURNAL

Infections Up to 76 Days After Stroke Increase Disability and Death

(2017) Annastazia E. Learoyd et al.   Translational Stroke Research

Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells

(2017) Lan-Feng Dong et al.   eLife

Association of Mitochondrial DNA Copy Number With Cardiovascular Disease

(2017) Foram N. Ashar et al.   JAMA Cardiology

Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study

(2016) Martin J O'Donnell et al.   LANCET

Adjusting MtDNA Quantification in Whole Blood for Peripheral Blood Platelet and Leukocyte Counts

(2016) Yamilee Hurtado-Roca et al.   PLoS One

The Opa1-Dependent Mitochondrial Cristae Remodeling Pathway Controls Atrophic, Apoptotic, and Ischemic Tissue Damage

(2015) Tatiana Varanita et al.   Cell Metabolism

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Mitochondrial DNA Copy Number and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Risk in Two Prospective Studies

(2014) C. Kim et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Mendelian randomization: genetic anchors for causal inference in epidemiological studies

(2014) G. Davey Smith et al.   HUMAN MOLECULAR GENETICS

Cardiovascular Risk and Events in 17 Low-, Middle-, and High-Income Countries

(2014) Salim Yusuf et al.   NEW ENGLAND JOURNAL OF MEDICINE

Simplified modified Rankin Scale questionnaire correlates with stroke severity

(2013) Askiel Bruno et al.   CLINICAL REHABILITATION

Is mitochondrial DNA content a potential biomarker of mitochondrial dysfunction?

(2012) Afshan N. Malik et al.   MITOCHONDRION

Index Event Bias as an Explanation for the Paradoxes of Recurrence Risk Research

(2011) Issa J. Dahabreh   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

APOE genotype and extent of bleeding and outcome in lobar intracerebral haemorrhage: a genetic association study

(2011) Alessandro Biffi et al.   LANCET NEUROLOGY

Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study

(2010) Martin J O'Donnell et al.   LANCET

Disability status at 1 month is a reliable proxy for final ischemic stroke outcome

(2010) B. Ovbiagele et al.   NEUROLOGY

Regionalized Pathology Correlates with Augmentation of mtDNA Copy Numbers in a Patient with Myoclonic Epilepsy with Ragged-Red Fibers (MERRF-Syndrome)

(2010) Anja Brinckmann et al.   PLoS One