Article
Virology
Idrissa Dieng, Marielton dos Passos Cunha, Moussa Moise Diagne, Pape Mbacke Sembene, Paolo Marinho de Andrade Zanotto, Ousmane Faye, Oumar Faye, Amadou Alpha Sall
Summary: The outbreak caused by DENV-1 in urban environments in Senegal and Mali after 2015 was attributed to a single viral introduction from Asia. The virus appeared to have been introduced directly into Medina Gounass, Senegal around 2014 and subsequently spread to other regions within Senegal before moving to neighboring Mali.
Article
Microbiology
Han Gao, Yong-jie Chen, Xiu-qiong Xu, Zhi-ying Xu, Si-jia Xu, Jia-bao Xing, Jing Liu, Yun-feng Zha, Yan-kuo Sun, Gui-hong Zhang
Summary: This study explored the origins, population characteristics, and transmission patterns of Senecavirus A (SVA) by analyzing representative SVA sequences from the GenBank database and newly isolated SVA strains. The study revealed that SVA originated in the United States and spread globally to different countries and regions. The analysis also provided insights into viral transmission routes and the risk of global virus prevalence.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Antonello Di Nardo, Luca Ferretti, Jemma Wadsworth, Valerie Mioulet, Boris Gelman, Sharon Karniely, Alexey Scherbakov, Ghulam Ziay, Fuat Ozyoruk, Unal Parlak, Pelin Tuncer-Goktuna, Reza Hassanzadeh, Mehdi Khalaj, Seyed Mohsen Dastoor, Darab Abdollahi, Ehtisham-Ul-Haq Khan, Muhammad Afzal, Manzoor Hussain, Nick J. Knowles, Donald P. King
Summary: The study maps the eco-evolutionary landscape of co-circulating foot-and-mouth disease virus (FMDV) lineages within an important endemic virus pool covering Western, Central, and parts of Southern Asia, reconstructing the evolutionary history and spatial dynamics over the last 20 years that have shaped the current epidemiological situation. It demonstrates that new FMDV variants periodically emerge from Southern Asia, leading to waves of virus incursions that systematically travel in a westerly direction. The research reveals how metapopulation dynamics drive the emergence and extinction of spatially structured virus populations, and how transmission in different host species regulates the evolutionary space of virus serotypes.
MOLECULAR BIOLOGY AND EVOLUTION
(2021)
Article
Virology
Enrique L. Louge Uriarte, Alejandra Badaracco, Maximiliano J. Spetter, Samuel Mino, Joaquin I. Armendano, Mark Zeller, Elisabeth Heylen, Ernesto Spath, Maria Rosa Leunda, Ana Rita Moreira, Jelle Matthijnssens, Viviana Parreno, Anselmo C. Odeon
Summary: This study compared RVA infections and G/P genotypes in beef and dairy calves in major livestock regions of Argentina, analyzed the evolutionary origin of a G8 strain, inferred the phylogenetic relationship of RVA field strains, and investigated the evolution and spatio-temporal dynamics of main G6 lineages in American countries.
Article
Virology
Monika Redlberger-Fritz, David N. Springer, Stephan W. Aberle, Jeremy V. Camp, Judith H. Aberle
Summary: In 2022, Austria experienced a severe RSV epidemic that started earlier than usual and affected more pediatric patients in emergency departments. Genomic surveillance and phylogenetic analysis revealed that the surge in the 2022/2023 season was driven by RSV-B, while the previous season was driven by RSV-A. The predominant genotype in the 2022/2023 season, RSV-B strain GB5.0.6a, emerged in late 2019. These findings provide valuable insights into RSV evolution and epidemiology for future monitoring and the development of vaccines and therapeutics.
JOURNAL OF MEDICAL VIROLOGY
(2023)
Article
Virology
Larissa Domingues Castilho de Arruda, Marta Giovanetti, Vagner Fonseca, Marina Castilhos Souza Umaki Zardin, Gislene Garcia de Castro Lichs, Silvia Asato, Ana Olivia Pascoto Esposito, Miriam Tokeshi Mueller, Joilson Xavier, Hegger Fritsch, Mauricio Lima, Carla de Oliveira, Elaine Vieira Santos, Livia de Mello Almeida Maziero, Danila Fernanda Rodrigues Frias, Danielle Ahad das Neves, Liliane Ferreira da Silva, Ellen Caroline Rodrigues Barretos, Paulo Eduardo Tsuha Oshiro, Bianca Modafari Goday, Jessica Klener Lemos dos Santos, Simone Kashima, Carlos F. C. de Albuquerque, Rodrigo Fabiano do Carmo Said, Alexander Rosewell, Luiz Henrique Ferraz Demarchi, Julio Croda, Luiz Carlos Junior Alcantara, CrhistinneCavalheiro Maymone Goncalves
Summary: Since its discovery in early 1916, dengue fever has caused extensive urban outbreaks in Brazil, posing a serious threat to public health. A genomic surveillance training program was conducted in collaboration with local health authorities, resulting in the generation of 177 DENV genome sequences collected during a period of high dengue fever cases. The study identified the co-circulation of different dengue serotypes and diverse viral lineages, indicating multiple introduction events of viral strains in the region. The findings highlight the complex and changing dynamics of DENV transmission and emphasize the value of ongoing surveillance activities in informing public health actions.
Article
Microbiology
Ighor Arantes, Tiago Graf, Paula Andrade, Yury Oliveira Chaves, Monick Lindenmeyer Guimaraes, Gonzalo Bello
Summary: The HIV-1 epidemic in Amazonas state is dominated by subtype B, but also has significant co-circulation of B-CAR and B-PAN variants. The study reveals that these two variants have different evolutionary histories but similar epidemic trajectories and transmissibility over the past two decades.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Infectious Diseases
Barbara Forro, Szilvia Marton, Eniko Feher, Marianna Doman, Gabor Kemenesi, Daniel Cadar, Akos Hornyak, Krisztian Banyai
Summary: European bat lyssavirus 1 (EBLV-1) is a widespread virus in bats across Europe, occasionally infecting domestic animals and humans. Subtyping revealed distinct geographic distributions for EBLV-1a and EBLV-1b, with recent EBLV-1a strains in Hungary showing positive selection in viral protein-coding genes. Evolutionary analysis suggests a major genetic clade of EBLV-1a isolates diverged in the 19th century, with recent ancestor divergence between Hungarian and Slovakian isolates traced back to 1950. Phylogeographic analysis indicates viral dispersal from Poland to Hungary, suggesting potential migratory spread of EBLV-1 strains across Europe.
TRANSBOUNDARY AND EMERGING DISEASES
(2021)
Article
Microbiology
Yongqiu Cui, Lei Hou, Yang Pan, Xufei Feng, Jianwei Zhou, Dedong Wang, Jinshuo Guo, Changzhe Liu, Yongyan Shi, Tong Sun, Xiaoyu Yang, Ning Zhu, Xinxin Tong, Yongxia Wang, Jue Liu
Summary: This study reconstructed the evolutionary origin, phylodynamics, and phylogeography of porcine circovirus type 3 (PCV3) based on available complete genome sequences. It was found that PCV3 had a closer relationship with bird circovirus than with bat circovirus, but their common ancestor was bat circovirus. The earliest origin of PCV3 was traced back to 1907.53-1923.44, with a substitution rate of 3.104 x 10(-4) to 6.8524 x 10(-4) substitution/site/year. Malaysia was identified as the earliest location of the original PCV3, which then migrated to Asia, America, and Europe.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Microbiology
Marina Siljic, Rastko Sehovic, Marko Jankovic, Gorana Stamenkovic, Ana Loncar, Marija Todorovic, Maja Stanojevic, Valentina Cirkovic
Summary: This study reveals the dual transmission routes of USUV in Central Europe and the spatio-temporal dynamics of USUV spread in the region. The data suggest a high potential for further USUV expansion in Europe, highlighting the need for enhanced surveillance.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Virology
Geovani de Oliveira Ribeiro, Danielle Elise Gill, Edcelha Soares D. Athaide Ribeiro, Fred Julio Costa Monteiro, Vanessa S. Morais, Roberta Marcatti, Marlisson Octavio da S. Rego, Emerson Luiz Lima Araujo, Steven S. Witkin, Fabiola Villanova, Xutao Deng, Ester Cerdeira Sabino, Eric Delwart, Elcio Leal, Antonio Charlys da Costa
Summary: This study analyzed the molecular epidemiological dynamics of DENV circulating in the Brazilian state of Amapa, identifying DENV-1 BR4 lineage introduced possibly from other states in northern Brazil around early 2010. Unique amino acid substitutions were found in the DENV-1 isolates from Amapa, indicating the potential of this new lineage to drive outbreaks of dengue in the Amazon region.
Article
Virology
Sachith Maduranga, Braulio Mark Valencia, Chathurani Sigera, Thiruni Adikari, Praveen Weeratunga, Deepika Fernando, Senaka Rajapakse, Andrew R. Lloyd, Rowena A. Bull, Chaturaka Rodrigo
Summary: Genomic surveillance is crucial for detecting severe community outbreaks of dengue virus, and a study in Sri Lanka found that DENV2 was the predominant serotype with occasional outbreaks of DENV3. The large outbreak of DENV3 in 2019 did not result in more severe disease, likely due to pre-existing immunity in the community.
Review
Veterinary Sciences
L. Carnegie, J. Raghwani, G. Fournie, S. C. Hill
Summary: This review summarizes how phylodynamic methods have and could contribute to the study of avian influenza viruses. It assesses how phylodynamics can be used to examine viral spread within and between bird populations, identify factors associated with virus dispersal, and determine the order and timing of virus lineage movement between regions or poultry production systems. Factors that can complicate the interpretation of phylodynamic results are discussed, and future methodological developments are identified to improve virus control.
Article
Virology
Eduardo D. Rodriguez-Aguilar, Jesus Martinez-Barnetche, Lilia Juarez-Palma, Alejandro Alvarado-Delgado, Cesar R. Gonzalez-Bonilla, Mario H. Rodriguez
Summary: This study analyzed the genetic characteristics of dengue fever outbreaks in Mexico, finding specific genotypes of DENV-1 and DENV-2 circulating during the outbreak and identifying the emergence of new lineages. The study also suggested that the virus may have spread from coastal regions and tourist destinations.
Article
Immunology
Karol Serwin, Antoine Chaillon, Kaja Scheibe, Anna Urbanska, Bogusz Aksak-Was, Piotr Zabek, Ewa Siwak, Iwona Cielniak, Elzbieta Jablonowska, Kamila Wojcik-Cichy, Pawel Jakubowski, Monika Bociaga-Jasik, Adam Witor, Bartosz Szetela, Milosz Parczewski
Summary: Geospatial A6 transmission networks are expanding in Poland, driven by local viral dispersal and cross-border migration from Ukraine. The recent war in Ukraine may contribute to further introductions, which could increase the burden of HIV in Western European countries.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Microbiology
Alessandra Soares-Schanoski, Natalia Baptista Cruz, Luiza Antunes de Castro-Jorge, Renan Villanova Homem de Carvalho, Cliomar Alves dos Santos, Nancy da Ros, Ursula Oliveira, Danuza Duarte Costa, Cecilia Luiza Simoes dos Santos, Marielton dos Passos Cunha, Maria Leonor Sarno Oliveira, Juliana Cardoso Alves, Regina Adalva de Lucena Couto Ocea, Danielle Rodrigues Ribeiro, Andre Nicolau Aquime Goncalves, Patricia Gonzalez-Dias, Andreas Suhrbier, Paolo Marinho de Andrade Zanotto, Inacio Junqueira de Azevedo, Dario S. Zamboni, Roque Pacheco Almeida, Paulo Lee Ho, Jorge Kalil, Milton Yutaka Nishiyama, Helder I. Nakaya
Article
Virology
Gabriela Barbosa, Amanda Caetano, Nathania Dabilla, Fernanda Franco, Marcelle Silva-Sales, Fabiola Fiaccadori, Menira Souza
JOURNAL OF MEDICAL VIROLOGY
(2020)
Article
Microbiology
Italo Araujo Castro, Lusmaia Damaceno Camargo Costa, Anniely Carvalho Reboucas Oliveira, Menira Souza, Divina das Dores de Paula Cardoso, Paulo Augusto Moreira Camargos, Paulo Sergio Sucasas Costa, Fabiola Souza Fiaccadori
BRAZILIAN JOURNAL OF MICROBIOLOGY
(2020)
Article
Virology
Idrissa Dieng, Marielton dos Passos Cunha, Moussa Moise Diagne, Pape Mbacke Sembene, Paolo Marinho de Andrade Zanotto, Ousmane Faye, Oumar Faye, Amadou Alpha Sall
Summary: The outbreak caused by DENV-1 in urban environments in Senegal and Mali after 2015 was attributed to a single viral introduction from Asia. The virus appeared to have been introduced directly into Medina Gounass, Senegal around 2014 and subsequently spread to other regions within Senegal before moving to neighboring Mali.
Letter
Virology
Amanda Caetano, Gabriela Barbosa, Nathania Dabilla, Fernanda Craveiro Franco, Fabiola Souza Fiaccadori, Menira Souza
JOURNAL OF MEDICAL VIROLOGY
(2021)
Article
Infectious Diseases
Marielton dos Passos Cunha, Amaro Nunes Duarte-Neto, Shahab Zaki Pour, Ludhmila Abrahao Hajjar, Fernando Pereira Frassetto, Marisa Dolhnikoff, Paulo Hilario do Nascimento Saldiva, Paolo Marinho de Andrade Zanotto
Summary: This study presents a fatal case of dengue infection associated with a newly introduced Dengue type 2 virus lineage in Brazil during the 2019 outbreak, which led to refractory shock and death in the patient.
BMC INFECTIOUS DISEASES
(2021)
Article
Multidisciplinary Sciences
Irina Yuri Kawashima, Maria Claudia Negret Lopez, Marielton dos Passos Cunha, Ronaldo Fumio Hashimoto
Summary: The genetic diversity of Coronaviruses gives them different biological abilities, and researchers have used a computational tool and Relative Synonymous Codon Usage to shed light on the molecular mechanisms of the SARS-CoV-2's host specificity. Bats are likely the natural host for this virus.
SCIENTIFIC REPORTS
(2022)
Article
Virology
Joao Paulo da Cruz Silva, Marielton dos Passos Cunha, Shahab Zaki Pour, Vitor Renaux Hering, Daniel Ferreira de Lima Neto, Paolo Marinho de Andrade Zanotto
Summary: This study identified unique peptide epitopes of the Chikungunya virus structural proteins E2 and E3 using immunoinformatic predictions and indirect peptide ELISA technique. Peptides P4 and P5 showed the highest reactivity and specificity among the analyzed epitopes, indicating their potential use in serological diagnostic trials and improving vaccine design for Chikungunya virus.
Article
Infectious Diseases
Marielton dos Passos Cunha, Amaro Nunes Duarte-Neto, Shahab Zaki Pour, Barbara Brito de Souza Pereira, Yeh-Li Ho, Beatriz Perondi, Jaques Sztajnbok, Venancio Avancini Ferreira Alves, Luiz Fernando Ferraz da Silva, Marisa Dolhnikoff, Paulo Hilario Nascimento Saldiva, Paolo Marinho de Andrade Zanotto
Summary: From 2016 to 2019, the largest outbreak of the Yellow Fever virus (YFV) in the Americas occurred in southeastern Brazil. The virus was transmitted through a sylvatic cycle near densely populated areas, such as the metropolitan region of Sao Paulo. The analysis of whole-genome sequences revealed that the outbreak originated in Goias in 2014 and spread through Minas Gerais before reaching Sao Paulo. The virus dispersed towards the east and south regions of Sao Paulo but did not establish an urban transmission cycle in the metropolitan region of Sao Paulo. The YFV from the south of Rio de Janeiro met with the virus moving east, while the virus carried to the south reached the southern states of Brazil.
PLOS NEGLECTED TROPICAL DISEASES
(2022)
Meeting Abstract
Zoology
Camila V. Molina, Marielton D. Cunha, Tiago F. da Silva, Cecilia Kierulff, Marcio Port-Carvalho, Lilian S. Fitorra, Haroldo R. Furuya, Bruno Petri, Liliane Milanelo, Mayra Frediani, Thais C. Sanches, Luana Rivas, Ticiana Zwarg, Joanna Malukiewicz, Fabio F. Videira, Claudia Igayara, Ivone Y. Kuribara, Fabiola Setim, Eduardo Gasparini-Junior, D. Junior Adriano, Helio T. Ramos, Ralyria Mello, Danielle B. Araujo, Luiz Gustavo B. Goes, Angelica Cristine D. Campos, Edison L. Durigon
AMERICAN JOURNAL OF PRIMATOLOGY
(2023)
Article
Virology
Martin Faye, Naimah Zein, Cheikh Loucoubar, Manfred Weidmann, Ousmane Faye, Marielton dos Passos Cunha, Paolo Marinho de Andrade Zanotto, Amadou Alpha Sall, Oumar Faye
Article
Infectious Diseases
Pedro Soares Porto, Deborah Anjos, Nathania Dabilla, Simone Goncalves da Fonseca, Menira Souza
INFECTION GENETICS AND EVOLUTION
(2020)
Article
Microbiology
Marielton dos Passos Cunha, Rafaella Sayuri Ioshino, Andre Luis Costa-da-Silva, Vivian Petersen, Margareth Lara Capurro, Paolo Marinho de Andrade Zanotto
MICROBIOLOGY RESOURCE ANNOUNCEMENTS
(2020)
