Natural and Synthetic Halogenated Amino Acids—Structural and Bioactive Features in Antimicrobial Peptides and Peptidomimetics

Biochemistry of fluoroprolines: the prospect of making fluorine a bioelement

(2021) Vladimir Kubyshkin et al.   Beilstein Journal of Organic Chemistry

Study of ground state interactions of enantiopure chiral quaternary ammonium salts and amides, nitroalkanes, nitroalkenes, esters, heterocycles, ketones and fluoroamides.

(2021) Mauro F A Adamo et al.   CHEMISTRY-A EUROPEAN JOURNAL

4-Fluoro-Threonine: From Diastereoselective Synthesis to pH-Dependent Conformational Equilibrium in Aqueous Solution

(2021) Simone Potenti et al.   ACS Omega

Protein Design with Fluoroprolines: 4,4‐Difluoroproline does not Eliminate the Rate‐limiting Step of Thioredoxin Folding

(2021) Jennie O’ Loughlin et al.   CHEMBIOCHEM

A Reduced Generalized Force Field for Biological Halogen Bonds

(2021) Melissa Coates Ford et al.   Journal of Chemical Theory and Computation

Fourth-Generation Analogues of the Anticancer Peptaibol Culicinin D: Probing the Effects of Hydrophobicity and Halogenation on Cytotoxicity

(2021) Iman Kavianinia et al.   SYNTHESIS-STUTTGART

Fluorine-19 NMR spectroscopy of fluorinated analogs of tritrpticin highlights a distinct role for Tyr residues in antimicrobial peptides

(2020) Mauricio Arias et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

What does fluorine do to a protein? Thermodynamic, and highly-resolved structural insights into fluorine-labelled variants of the cold shock protein

(2020) Hannah Welte et al.   Scientific Reports

Structure and composition of the tunic in the sea pineapple Halocynthia roretzi: A complex cellulosic composite biomaterial

(2020) Geonho Song et al.   Acta Biomaterialia

Cytotoxicity of Halogenated Tyrosyl Compounds, an Emerging Class of Disinfection Byproducts

(2020) Dayong Tian et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Bioinformatics and Biosimulations as Toolbox for Peptides and Peptidomimetics Design: Where Are We?

(2020) Ilda D’Annessa et al.   Frontiers in Molecular Biosciences

Incorporation of Halogenated Amino Acids into Antibody Fragments at Multiple Specific Sites Enhances Antigen Binding

(2020) Akiko Hayashi et al.   CHEMBIOCHEM

Design, Synthesis and Biological Evaluation of Biphenylglyoxamide-Based Small Molecular Antimicrobial Peptide Mimics as Antibacterial Agents

(2020) Tsz Tin Yu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Indolicidin analogs with broad-spectrum antimicrobial activity and low hemolytic activity

(2020) M.P. Smirnova et al.   PEPTIDES

Halogenation as a tool to tune antimicrobial activity of peptoids

(2020) Natalia Molchanova et al.   Scientific Reports

Antimicrobial and antitumor activity of peptidomimetics synthesized from amino acids

(2020) Huan Li et al.   BIOORGANIC CHEMISTRY

Fluorinated O-phenylserine residues enhance the broad-spectrum antimicrobial activity of ultrashort cationic lipopeptides

(2020) Hugh D. Glossop et al.   JOURNAL OF FLUORINE CHEMISTRY

Tuning the Biological Activity of RGD Peptides with Halotryptophans

(2020) Isabell Kemker et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Antimicrobial Peptide, Bactenecin 5, Supports Cell-Mediated but Not Humoral Immunity in the Context of a Mycobacterial Antigen Vaccine Model

(2020) Tulika Munshi et al.   Antibiotics-Basel

In vitro and in vivo properties of the bovine antimicrobial peptide, Bactenecin 5

(2019) R. L. Price et al.   PLoS One

Cationic Amphipathic Triazines with Potent Anti-bacterial, Anti-inflammatory and Anti-atopic Dermatitis Properties

(2019) Pethaiah Gunasekaran et al.   Scientific Reports

Design, recombinant expression, and antibacterial activity of a novel hybrid magainin–thanatin antimicrobial peptide

(2019) Lu Tian et al.   PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY

Discovery of a pathway for terminal-alkyne amino acid biosynthesis

(2019) J. A. Marchand et al.   NATURE

Enantioselective Desymmetrization of cis-3,5-O-Arylidenecyclohexanones Catalyzed by Cinchona-Derived Quaternary Ammonium Salts

(2019) Mauro Cortigiani et al.   JOURNAL OF ORGANIC CHEMISTRY

Molecular simulation of peptides coming of age: Accurate prediction of folding, dynamics and structures

(2019) Panagiota S. Georgoulia et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Hybrids made from antimicrobial peptides with different mechanisms of action show enhanced membrane permeabilization

(2019) Heidi M. Wade et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Halogenated Tyrosine Derivatives from the Tropical Eastern Pacific Zoantharians Antipathozoanthus hickmani and Parazoanthus darwini

(2019) Paul O. Guillen et al.   JOURNAL OF NATURAL PRODUCTS

Bromotryptophan and its Analogs in Peptides from Marine Animals

(2019) Elsie C. Jimenez   PROTEIN AND PEPTIDE LETTERS

Alternatives to Conventional Antibiotics in the Era of Antimicrobial Resistance

(2019) Chandradhish Ghosh et al.   TRENDS IN MICROBIOLOGY

Chemoenzymatic Platform for Synthesis of Chiral Organofluorines Based on Type II Aldolases

(2019) Jason Fang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Redesigning Arenicin-1, an Antimicrobial Peptide from the Marine Polychaeta Arenicola marina, by Strand Rearrangement or Branching, Substitution of Specific Residues, and Backbone Linearization or Cyclization

(2019) Dmitriy S. Orlov et al.   Marine Drugs

Approaches to Obtaining Fluorinated α-Amino Acids

(2019) Johann Moschner et al.   CHEMICAL REVIEWS

Late‐Stage Diversification of Indole Containing Biomolecules

(2019) Hendrik Gruß et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Distinct Conformational Landscapes of 4 S ‐Substituted Prolines That Promote an endo Ring Pucker

(2019) Nicholas V. Costantini et al.   CHEMISTRY-A EUROPEAN JOURNAL

Conotoxins: Chemistry and Biology

(2019) Ai-Hua Jin et al.   CHEMICAL REVIEWS

Proline‐Rich Peptides with Improved Antimicrobial Activity against E. coli , K. pneumoniae , and A. baumannii

(2019) Mario Mardirossian et al.   ChemMedChem

Applications of fluorine-containing amino acids for drug design

(2019) Haibo Mei et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antimicrobial Efficacy of Indolicidin Against Multi-Drug Resistant Enteroaggregative Escherichia coli in a Galleria mellonella Model

(2019) Jess Vergis et al.   Frontiers in Microbiology

Molecular modelling of epitopes recognized by neoplastic B lymphocytes in Chronic Lymphocytic Leukemia

(2019) Antonio Lupia et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antimicrobial activity of amphipathic α,α-disubstituted β-amino amide derivatives against ESBL – CARBA producing multi-resistant bacteria; effect of halogenation, lipophilicity and cationic character

(2019) Marianne H. Paulsen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The Role of Formyl Peptide Receptors for Immunomodulatory Activities of Antimicrobial Peptides and Peptidomimetics

(2018) Sarah Line Skovbakke et al.   CURRENT PHARMACEUTICAL DESIGN

Fine-Tuning the Proteolytic Stability of Peptides with Fluorinated Amino Acids

(2018) Susanne Huhmann et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Recent insights into structure-function relationships of antimicrobial peptides

(2018) Tamer A.E. Ahmed et al.   JOURNAL OF FOOD BIOCHEMISTRY

Design, expression, and characterization of the hybrid antimicrobial peptide T-catesbeianin-1 based on FyuA

(2018) Huihui Xu et al.   JOURNAL OF PEPTIDE SCIENCE

Fluorinated antimicrobial lysine-based peptidomimetics with activity against methicillin-resistant Staphylococcus pseudintermedius

(2018) Natalia Molchanova et al.   JOURNAL OF PEPTIDE SCIENCE

Antimicrobial Peptides: Features, Action, and Their Resistance Mechanisms in Bacteria

(2018) Hoda Moravej et al.   Microbial Drug Resistance

An overview of recent molecular dynamics applications as medicinal chemistry tools for the undruggable site challenge

(2018) Ugo Perricone et al.   MedChemComm

Biosynthesis and biotechnological application of non-canonical amino acids: Complex and unclear

(2018) Huibin Zou et al.   BIOTECHNOLOGY ADVANCES

Amino Acid Hot Spots of Halogen Bonding: A Combined Theoretical and Experimental Case Study of the 5-HT7 Receptor

(2018) Rafał Kurczab et al.   JOURNAL OF MEDICINAL CHEMISTRY

An amphipathic cyclic tetrapeptide scaffold containing halogenated β2,2 -amino acids with activity against multiresistant bacteria

(2018) Marianne H. Paulsen et al.   JOURNAL OF PEPTIDE SCIENCE

One-Pot Synthesis of d-Halotryptophans by Dynamic Stereoinversion Using a Specific l-Amino Acid Oxidase

(2018) Christian Schnepel et al.   ACS Catalysis

The effect of halogenation on the antimicrobial activity, antibiofilm activity, cytotoxicity and proteolytic stability of the antimicrobial peptide Jelleine-I

(2018) Fengjing Jia et al.   PEPTIDES

Metabolic engineering of Corynebacterium glutamicum for the fermentative production of halogenated tryptophan

(2018) Kareen H. Veldmann et al.   JOURNAL OF BIOTECHNOLOGY

An overview of antimicrobial peptides and the latest advances in their development

(2017) Josep M Sierra et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

The response of human bacteria to static magnetic field and radiofrequency electromagnetic field

(2017) David P. E. Crabtree et al.   JOURNAL OF MICROBIOLOGY

Determination of the Halogenated Skeleton Constituents of the Marine Demosponge Ianthella basta

(2017) Susanne Ueberlein et al.   Marine Drugs

Advances in Development of Antimicrobial Peptidomimetics as Potential Drugs

(2017) et al.   MOLECULES

Reaction of azides and enolisable aldehydes under the catalysis of organic bases and Cinchona based quaternary ammonium salts

(2017) Dario Destro et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Exploring the links between peptoid antibacterial activity and toxicity

(2017) H. L. Bolt et al.   MedChemComm

Prospects of In vivo Incorporation of Non-canonical Amino Acids for the Chemical Diversification of Antimicrobial Peptides

(2017) Tobias Baumann et al.   Frontiers in Microbiology

Stereoselective Organocatalyzed Synthesis of α-Fluorinated β-Amino Thioesters and Their Application in Peptide Synthesis

(2016) Elena Cosimi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Lantibiotic NAI-107 Efficiently Rescues Drosophila melanogaster from Infection with Methicillin-Resistant Staphylococcus aureus USA300

(2016) Thomas T. Thomsen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Recombinant expression, antimicrobial activity and mechanism of action of tritrpticin analogs containing fluoro-tryptophan residues

(2016) Mauricio Arias et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The therapeutic applications of antimicrobial peptides (AMPs): a patent review

(2016) Hee-Kyoung Kang et al.   JOURNAL OF MICROBIOLOGY

Efficient and scalable synthesis of α,α-disubstituted β-amino amides

(2016) Marianne Hagensen Paulsen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective cyclopropanation of (Z)-3-substituted-2-(4-pyridyl)-acrylonitriles catalyzed by Cinchona ammonium salts

(2016) Claudia Del Fiandra et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Antimicrobial Peptides: An Emerging Category of Therapeutic Agents

(2016) Margit Mahlapuu et al.   Frontiers in Cellular and Infection Microbiology

Novel Antimicrobial Peptides EeCentrocins 1, 2 and EeStrongylocin 2 from the Edible Sea Urchin Echinus esculentus Have 6-Br-Trp Post-Translational Modifications

(2016) Runar Gjerp Solstad et al.   PLoS One

The Important Role of Halogen Bond in Substrate Selectivity of Enzymatic Catalysis

(2016) Shuiqin Jiang et al.   Scientific Reports

Acceleration of the Rate-Limiting Step of Thioredoxin Folding by Replacement of its Conservedcis-Proline with (4 S)-Fluoroproline

(2015) Daniel Roderer et al.   CHEMBIOCHEM

Antimicrobial Peptide Structure and Mechanism of Action: A Focus on the Role of Membrane Structure

(2015) Tzong-Hsien Lee et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Non-Membrane Permeabilizing Modes of Action of Antimicrobial Peptides on Bacteria

(2015) Marco Scocchi et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Methodology for Synthesis of Enantiopure 3,5-Disubstituted Pyrrol-2-ones

(2015) Ondřej Krenk et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Antimicrobial Peptides with Potential for Biofilm Eradication: Synthesis and Structure Activity Relationship Studies of Battacin Peptides

(2015) Gayan Heruka De Zoysa et al.   JOURNAL OF MEDICINAL CHEMISTRY

Brominated Variant of the Lantibiotic NAI-107 with Enhanced Antibacterial Potency

(2015) João C. S. Cruz et al.   JOURNAL OF NATURAL PRODUCTS

Amino Acid-Derived Metabolites from the Ascidian Aplidium sp.

(2015) Tae Won et al.   Marine Drugs

The Potential Use of Natural and Structural Analogues of Antimicrobial Peptides in the Fight against Neglected Tropical Diseases

(2015) Angélique Lewies et al.   MOLECULES

An improved procedure to prepare 3-methyl-4-nitroalkylenethylisoxazoles and their reaction under catalytic enantioselective Michael addition with nitromethane

(2015) Maria Moccia et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

γ-(S)-Trifluoromethyl proline: evaluation as a structural substitute of proline for solid state 19F-NMR peptide studies

(2015) Vladimir Kubyshkin et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Transcriptional responses of invasive and indigenous whiteflies to different host plants reveal their disparate capacity of adaptation

(2015) Hong-Xing Xu et al.   Scientific Reports

Acceleration of protein folding by four orders of magnitude through a single amino acid substitution

(2015) Daniel J. A. Roderer et al.   Scientific Reports

Cyclopropanation of 5-(1-Bromo-2-phenyl-vinyl)-3-methyl-4-nitro-isoxazoles under Phase Transfer Catalysis (PTC) Conditions

(2015) Linda Piras et al.   Catalysts

Impacts of terminal (4R)-fluoroproline and (4S)-fluoroproline residues on polyproline conformation

(2014) Yu-Ju Lin et al.   AMINO ACIDS

Automated solid-phase peptide synthesis to obtain therapeutic peptides

(2014) Veronika Mäde et al.   Beilstein Journal of Organic Chemistry

Identification of Fluorinases fromStreptomycessp MA37,Norcardia brasiliensis, andActinoplanessp N902-109 by Genome Mining

(2014) Hai Deng et al.   CHEMBIOCHEM

Applying γ-Substituted Prolines in theFoldonPeptide: Polarity Contradicts Preorganization

(2014) Dennis Dietz et al.   CHEMBIOCHEM

Peptidomimetics via modifications of amino acids and peptide bonds

(2014) Ilker Avan et al.   CHEMICAL SOCIETY REVIEWS

The Host Antimicrobial Peptide Bac71-35 Binds to Bacterial Ribosomal Proteins and Inhibits Protein Synthesis

(2014) Mario Mardirossian et al.   CHEMISTRY & BIOLOGY

Small Molecular Antibacterial Peptoid Mimics: The Simpler the Better!

(2014) Chandradhish Ghosh et al.   JOURNAL OF MEDICINAL CHEMISTRY

Characterization of the Congeners in the Lantibiotic NAI-107 Complex

(2014) Sonia I. Maffioli et al.   JOURNAL OF NATURAL PRODUCTS

Force Field Model of Periodic Trends in Biomolecular Halogen Bonds

(2014) Matthew R. Scholfield et al.   JOURNAL OF PHYSICAL CHEMISTRY B

The Skeletal Amino Acid Composition of the Marine Demosponge Aplysina cavernicola

(2014) Susanne Ueberlein et al.   Marine Drugs

Regioselective Arene Halogenation using the FAD-Dependent Halogenase RebH

(2013) James T. Payne et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

pH Dependence of Microbe Sterilization by Cationic Antimicrobial Peptides

(2013) William F. Walkenhorst et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

(4R)- and (4S)-Fluoroproline in the Conservedcis-Prolyl Peptide Bond of the Thioredoxin Fold: Tertiary Structure Context Dictates Ring Puckering

(2013) Marina Rubini et al.   CHEMBIOCHEM

Halogen bonding in complexes of proteins and non-natural amino acids

(2013) Sunčica Z. Borozan et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Catalysis by Desolvation: The Catalytic Prowess of SAM-Dependent Halide-Alkylating Enzymes

(2013) Danielle C. Lohman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Insights into the mechanism of interaction between trehalose-conjugated beta-sheet breaker peptides and Aβ(1–42) fibrils by molecular dynamics simulations

(2013) Ida Autiero et al.   Molecular BioSystems

AApeptides as a new class of antimicrobial agents

(2013) Youhong Niu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Both the cis-trans equilibrium and isomerization dynamics of a single proline amide modulate  2-microglobulin amyloid assembly

(2013) V. Y. Torbeev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Scalable synthesis of γ-thiolysine starting from lysine and a side by side comparison with δ-thiolysine in non-enzymatic ubiquitination

(2013) Remco Merkx et al.   Chemical Science

The impact of either 4-R-hydroxyproline or 4-R-fluoroproline on the conformation and SH3m-cort binding of HPK1 proline-rich peptide

(2012) Andrea Borgogno et al.   AMINO ACIDS

Phase transfer catalyzed enantioselective cyclopropanation of 4-nitro-5-styrylisoxazoles

(2012) Claudia Del Fiandra et al.   CHEMICAL COMMUNICATIONS

Scalable Anisotropic Shape and Electrostatic Models for Biological Bromine Halogen Bonds

(2012) Megan Carter et al.   Journal of Chemical Theory and Computation

Antimicrobial Activity of Peptidomimetics against Multidrug-Resistant Escherichia coli: A Comparative Study of Different Backbones

(2012) Rasmus D. Jahnsen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design of Peptide and Peptidomimetic Ligands with Novel Pharmacological Activity Profiles

(2011) Victor J. Hruby et al.   Annual Review of Pharmacology and Toxicology

Efficacy of the New Lantibiotic NAI-107 in Experimental Infections Induced by Multidrug-Resistant Gram-Positive Pathogens

(2011) Daniela Jabés et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Proline-rich antimicrobial peptides: converging to a non-lytic mechanism of action

(2011) Marco Scocchi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Halogen bonding in halocarbon–protein complexes: a structural survey

(2011) Emilio Parisini et al.   CHEMICAL SOCIETY REVIEWS

Fluorinated amino acids: compatibility with native protein structures and effects on protein–protein interactions

(2011) Mario Salwiczek et al.   CHEMICAL SOCIETY REVIEWS

Antimicrobial peptides: key components of the innate immune system

(2011) Mukesh Pasupuleti et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Biostructural Features of Additional Jasplakinolide (Jaspamide) Analogues

(2011) Katharine R. Watts et al.   JOURNAL OF NATURAL PRODUCTS

Antiparasitic Bromotyrosine Derivatives from the Marine Sponge Verongula rigida

(2011) Elkin Galeano et al.   Marine Drugs

Rational Design of Protein Stability: Effect of (2S,4R)-4-Fluoroproline on the Stability and Folding Pathway of Ubiquitin

(2011) Maria D. Crespo et al.   PLoS One

Current applications of 19F NMR to studies of protein structure and dynamics

(2011) Julianne L. Kitevski-LeBlanc et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

The expanding scope of antimicrobial peptide structures and their modes of action

(2011) Leonard T. Nguyen et al.   TRENDS IN BIOTECHNOLOGY

The C–F bond as a conformational tool in organic and biological chemistry

(2010) Luke Hunter   Beilstein Journal of Organic Chemistry

Synthetic Biology of Protein Folding

(2010) Luis Moroder et al.   CHEMPHYSCHEM

Structural Aspects of Plant Antimicrobial Peptides

(2010) Lara Padovan et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Centrocins: Isolation and characterization of novel dimeric antimicrobial peptides from the green sea urchin, Strongylocentrotus droebachiensis

(2010) Chun Li et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Iodocionin, a Cytotoxic Iodinated Metabolite from the Mediterranean Ascidian Ciona edwardsii

(2010) Anna Aiello et al.   Marine Drugs

Catalytic Asymmetric Conjugate Addition of Nitroalkanes to 4-Nitro-5-styrylisoxazoles

(2009) Andrea Baschieri et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Collagen Structure and Stability

(2009) Matthew D. Shoulders et al.   Annual Review of Biochemistry

Peptoid-Peptide Hybrid Backbone Architectures

(2009) Christian A. Olsen   CHEMBIOCHEM

Lantibiotics: Mode of Action, Biosynthesis and Bioengineering

(2009) G. Bierbaum et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Anionic Antimicrobial Peptides from Eukaryotic Organisms

(2009) Frederick Harris et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

The Proline-rich Antibacterial Peptide Bac7 Binds to and Inhibits in vitro the Molecular Chaperone DnaK

(2009) Marco Scocchi et al.   International Journal of Peptide Research and Therapeutics

C−X···H Contacts in Biomolecular Systems: How They Contribute to Protein−Ligand Binding Affinity

(2009) Yunxiang Lu et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Nature of Amide Carbonyl−Carbonyl Interactions in Proteins

(2009) Amit Choudhary et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Two New Jaspamide Derivatives from the Marine Sponge Jaspis splendens

(2009) Sherif Ebada et al.   Marine Drugs

Fluorine—a new element in the design of membrane-active peptides

(2009) E. Neil G. Marsh et al.   Molecular BioSystems

Antimicrobial peptides: linking partition, activity and high membrane-bound concentrations

(2009) Manuel N. Melo et al.   NATURE REVIEWS MICROBIOLOGY

New Insights into the Mechanism of Enzymatic Chlorination of Tryptophan

(2008) Silvana Flecks et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Fluorous Effect in Proteins: Properties of α4F6, a 4-α-Helix Bundle Protein with a Fluorocarbon Core†

(2008) Lindsey M. Gottler et al.   BIOCHEMISTRY

Antimicrobial peptide mimics for improved therapeutic properties

(2008) Shahar Rotem et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Using Fluorous Amino Acids to Modulate the Biological Activity of an Antimicrobial Peptide

(2008) Lindsey M. Gottler et al.   CHEMBIOCHEM

Determining the Structure and Mode of Action of Microbisporicin, a Potent Lantibiotic Active Against Multiresistant Pathogens

(2008) Franca Castiglione et al.   CHEMISTRY & BIOLOGY

Strongylocins, novel antimicrobial peptides from the green sea urchin, Strongylocentrotus droebachiensis

(2008) Chun Li et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Antifouling Activity of a Dibrominated Cyclopeptide from the Marine SpongeGeodia barretti⊥

(2008) Erik Hedner et al.   JOURNAL OF NATURAL PRODUCTS

Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides

(2008) N. P. Chongsiriwatana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cl-π interactions in protein-ligand complexes

(2008) Yumi N. Imai et al.   PROTEIN SCIENCE