期刊
MOLECULAR BIOLOGY REPORTS
卷 49, 期 3, 页码 2393-2411出版社
SPRINGER
DOI: 10.1007/s11033-021-06997-4
关键词
Applications; Bio-banking; Fish cell line; Cell-based aquaculture; In vitro research
资金
- Department of Biotechnology, Govt. of India, New Delhi
Cell lines derived from fish have emerged as a valuable tool for studying various aspects of aquaculture and have been particularly useful for toxicological, pathological, and immunological studies. The development of new fish cell lines has generated significant interest, and their characterization and maintenance are critical for ensuring the reliability of scientific research in vitro.
Introduction Cell line derived from fish has been established as a promising tool for studying many key issues of aquaculture covering fish growth, disease, reproduction, genetics, and biotechnology. In addition, fish cell lines are very useful in vitro models for toxicological, pathological, and immunological studies. The easier maintenance of fish cell lines in flexible temperature regimes and hypoxic conditions make them preferable in vitro tools over mammalian cell lines. Great excitement has been observed in establishing and characterizing new fish cell lines representing diverse fish species and tissue types. The well-characterized and authenticated cell lines are of utmost essential as these represent cellular functions very similar to in vivo state of an organism otherwise it would affect the reproducibility of scientific research. Conclusion The fish cell lines have exhibited encouraging results in several key aspects of in vitro research in aquaculture including virology, nutrition and metabolism, production of vaccines, and transgenic fish production. The review paper reports the cell lines developed from fish, their characterization, and biobanking along with their potential applications and challenges in in vitro research.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据