Integrated liver and plasma proteomics in obese mice reveals complex metabolic regulation

Review of galectin-3 inhibitors in the treatment of nonalcoholic steatohepatitis

(2021) Atef Al Attar et al.   Expert Review of Clinical Pharmacology

Trans-omic analysis reveals obesity-associated dysregulation of inter-organ metabolic cycles between the liver and skeletal muscle

(2021) Riku Egami et al.   iScience

Discovery of Thymosin Beta-4 as a Human Exerkine and Growth Factor

(2021) Alba Gonzalez-Franquesa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis–like phenotypes

(2021) Morten Dall et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Is Alzheimer’s Disease a Liver Disease of the Brain?

(2020) Margaret F. Bassendine et al.   JOURNAL OF ALZHEIMERS DISEASE

Blockade of High-Fat Diet Proteomic Phenotypes using Exercise as Prevention or Treatment

(2020) Sergio F. Martinez-Huenchullan et al.   MOLECULAR & CELLULAR PROTEOMICS

Beyond cells: The extracellular circulating 20S proteasomes

(2020) Vandita Dwivedi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Plasma proteome profiling discovers novel proteins associated with non‐alcoholic fatty liver disease

(2019) Lili Niu et al.   Molecular Systems Biology

Proteomics Analysis of Skeletal Muscle from Leptin-Deficient ob/ob Mice Reveals Adaptive Remodeling of Metabolic Characteristics and Fiber Type Composition

(2018) Milena Schönke et al.   PROTEOMICS

Mechanisms Preserving Insulin Action during High Dietary Fat Intake

(2018) Anne-Marie Lundsgaard et al.   Cell Metabolism

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Plasma Proteome Profiling Reveals Dynamics of Inflammatory and Lipid Homeostasis Markers after Roux-En-Y Gastric Bypass Surgery

(2018) Nicolai J. Wewer Albrechtsen et al.   Cell Systems

New trends on obesity and NAFLD in Asia

(2017) Jian-Gao Fan et al.   JOURNAL OF HEPATOLOGY

Proteasome activity related with the daily physical activity of COPD patients

(2017) Kang-Yun Lee et al.   International Journal of Chronic Obstructive Pulmonary Disease

Preclinical models for obesity research

(2016) Perry Barrett et al.   Disease Models & Mechanisms

Endoplasmic reticulum stress in obesity and obesity-related disorders: An expanded view

(2016) Michael J. Pagliassotti et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Proteomics reveals the effects of sustained weight loss on the human plasma proteome

(2016) Philipp E Geyer et al.   Molecular Systems Biology

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

The MaxQuant computational platform for mass spectrometry-based shotgun proteomics

(2016) Stefka Tyanova et al.   Nature Protocols

Leptin Regulation of Immune Responses

(2016) Caitlin Naylor et al.   TRENDS IN MOLECULAR MEDICINE

Plasma Proteome Profiling to Assess Human Health and Disease

(2016) Philipp E. Geyer et al.   Cell Systems

Integrin α1-null Mice Exhibit Improved Fatty Liver When Fed a High Fat Diet Despite Severe Hepatic Insulin Resistance

(2015) Ashley S. Williams et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extending the Limits of Quantitative Proteome Profiling with Data-Independent Acquisition and Application to Acetaminophen-Treated Three-Dimensional Liver Microtissues

(2015) Roland Bruderer et al.   MOLECULAR & CELLULAR PROTEOMICS

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Nonalcoholic fatty liver disease: A main driver of insulin resistance or a dangerous liaison?

(2014) Nanda Gruben et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A “Proteomic Ruler” for Protein Copy Number and Concentration Estimation without Spike-in Standards

(2014) Jacek R. Wiśniewski et al.   MOLECULAR & CELLULAR PROTEOMICS

Peroxisome biogenesis in mammalian cells

(2014) Yukio Fujiki et al.   Frontiers in Physiology

Eplerenone ameliorates the phenotypes of metabolic syndrome with NASH in liver-specific SREBP-1c Tg mice fed high-fat and high-fructose diet

(2013) Tsutomu Wada et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Prognostic Value of Changes in Galectin-3 Levels Over Time in Patients With Heart Failure

(2013) A. Rogier van der Velde et al.   Circulation-Heart Failure

Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver disease

(2013) Yuki Kawano et al.   JOURNAL OF GASTROENTEROLOGY

Caspase-1 as a Central Regulator of High Fat Diet-Induced Non-Alcoholic Steatohepatitis

(2013) Laura J. Dixon et al.   PLoS One

Protein Folding in the Endoplasmic Reticulum

(2013) I. Braakman et al.   Cold Spring Harbor Perspectives in Biology

Dyslipidemia in Obesity: Mechanisms and Potential Targets

(2013) Boudewijn Klop et al.   Nutrients

Pex11α deficiency impairs peroxisome elongation and division and contributes to nonalcoholic fatty liver in mice

(2012) Huachun Weng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Consecutive Proteolytic Digestion in an Enzyme Reactor Increases Depth of Proteomic and Phosphoproteomic Analysis

(2012) Jacek R. Wiśniewski et al.   ANALYTICAL CHEMISTRY

Genetic and Pharmacological Inhibition of Galectin-3 Prevents Cardiac Remodeling by Interfering With Myocardial Fibrogenesis

(2012) Lili Yu et al.   Circulation-Heart Failure

Regulation of hepatocyte fate by interferon-γ

(2011) Christopher J. Horras et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Pathology of the liver in obese and diabetic ob/ob and db/db mice fed a standard or high-calorie diet

(2011) Viviane Trak-Smayra et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Obesity-Related Derangements of Coagulation and Fibrinolysis: A Study of Obesity-Discordant Monozygotic Twin Pairs

(2011) Sanna M. Kaye et al.   Obesity

Body mass index in midlife and late-life as a risk factor for dementia: a meta-analysis of prospective studies

(2011) K. J. Anstey et al.   Obesity Reviews

Human Fatty Liver Disease: Old Questions and New Insights

(2011) J. C. Cohen et al.   SCIENCE

Epidemiology of Non-Alcoholic Fatty Liver Disease

(2010) Stefano Bellentani et al.   DIGESTIVE DISEASES

Serum Galectin-3 Is Elevated in Obesity and Negatively Correlates with Glycosylated Hemoglobin in Type 2 Diabetes

(2010) Johanna Weigert et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

Whole blood aggregation and coagulation in db/db and ob/ob mouse models of type 2 diabetes

(2009) Melissa L Henry et al.   BLOOD COAGULATION & FIBRINOLYSIS

The relationship between serum galectin-3 and serum markers of cardiac extracellular matrix turnover in heart failure patients

(2009) Yen-Hung Lin et al.   CLINICA CHIMICA ACTA

Therapeutic Targets in Extracellular Protein Deposition Diseases

(2009) A. Wyatt et al.   CURRENT MEDICINAL CHEMISTRY

GRP78 expression inhibits insulin and ER stress–induced SREBP-1c activation and reduces hepatic steatosis in mice

(2009) Hélène L. Kammoun et al.   JOURNAL OF CLINICAL INVESTIGATION

Galectin-3 Is an Amplifier of Inflammation in Atherosclerotic Plaque Progression Through Macrophage Activation And Monocyte Chemoattraction

(2007) Marianna Papaspyridonos et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY