Therapeutic effect of targeting Substance P on the progression of osteoarthritis

Role of vasoactive intestinal peptide in the progression of osteoarthritis through bone sclerosis and angiogenesis in subchondral bone

(2020) Munekazu Kanemitsu et al.   JOURNAL OF ORTHOPAEDIC SCIENCE

Sensory neuropeptides are required for bone and cartilage homeostasis in a murine destabilization-induced osteoarthritis model

(2020) Dominique Muschter et al.   BONE

Histological scoring system for subchondral bone changes in murine models of joint aging and osteoarthritis

(2020) Keita Nagira et al.   Scientific Reports

Substance P accelerates wound repair by promoting neovascularization and preventing inflammation in an ischemia mouse model

(2019) Suna Kim et al.   LIFE SCIENCES

Substance P blocks the impairment of paracrine potential of MSC due to long term culture

(2018) Sang-Min Baek et al.   Molecular & Cellular Toxicology

Skin Regeneration with Self-Assembled Peptide Hydrogels Conjugated with Substance P in a Diabetic Rat Model

(2018) Ji Eun Kim et al.   TISSUE ENGINEERING PART A

Substance P and pain chronicity

(2018) W. Zieglgänsberger   CELL AND TISSUE RESEARCH

The role of nervous system in adaptive response of bone to mechanical loading

(2018) Yini Qiao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Peripheral Nerve Fibers and Their Neurotransmitters in Osteoarthritis Pathology

(2017) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of Substance P Neuropeptide in Inflammation, Wound Healing, and Tissue Homeostasis

(2017) Susmit Suvas   JOURNAL OF IMMUNOLOGY

Therapeutic effects of neuropeptide substance P coupled with self-assembled peptide nanofibers on the progression of osteoarthritis in a rat model

(2016) Sang Jun Kim et al.   BIOMATERIALS

5-HT3receptors promote colonic inflammation via activation of substance P/neurokinin-1 receptors in dextran sulphate sodium-induced murine colitis

(2016) Daichi Utsumi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neuropeptide substance P and the immune response

(2016) Alireza Mashaghi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Attenuation of cartilage degeneration by calcitonin gene-related paptide receptor antagonist via inhibition of subchondral bone sclerosis in osteoarthritis mice

(2016) Tomoyuki Nakasa et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Bach1 deficiency reduces severity of osteoarthritis through upregulation of heme oxygenase-1

(2015) Tsuyoshi Takada et al.   ARTHRITIS RESEARCH & THERAPY

Substance P ameliorates collagen II-induced arthritis in mice via suppression of the inflammatory response

(2014) Hyun Sook Hong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Local injection of substance P increases bony formation during mandibular distraction osteogenesis in rats

(2014) Ya-bo Zhang et al.   BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY

The role of peripheral nerve fibers and their neurotransmitters in cartilage and bone physiology and pathophysiology

(2014) Susanne Grässel   ARTHRITIS RESEARCH & THERAPY

Osteoarthritis: A disease of the joint as an organ

(2012) Richard F. Loeser et al.   ARTHRITIS AND RHEUMATISM

Substance P induces M2-type macrophages after spinal cord injury

(2012) Mei H. Jiang et al.   NEUROREPORT

Relationship between cartilage and subchondral bone lesions in repetitive impact trauma-induced equine osteoarthritis

(2012) M. Lacourt et al.   OSTEOARTHRITIS AND CARTILAGE

Substance P and norepinephrine modulate murine chondrocyte proliferation and apoptosis

(2011) Alfred Opolka et al.   ARTHRITIS AND RHEUMATISM

Investigating ADAMTS-mediated aggrecanolysis in mouse cartilage

(2011) Heather Stanton et al.   Nature Protocols

Acute joint pathology and synovial inflammation is associated with increased intra-articular fracture severity in the mouse knee

(2011) J.S. Lewis et al.   OSTEOARTHRITIS AND CARTILAGE

Substance P stimulates the recovery of bone marrow after the irradiation

(2010) You Sun An et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the mouse

(2010) S.S. Glasson et al.   OSTEOARTHRITIS AND CARTILAGE

Substance P stimulates bone marrow stromal cell osteogenic activity, osteoclast differentiation, and resorption activity in vitro

(2009) Liping Wang et al.   BONE

Detection of pain-related molecules in the subchondral bone of osteoarthritic knees

(2009) Shuhei Ogino et al.   CLINICAL RHEUMATOLOGY

A new role of substance P as an injury-inducible messenger for mobilization of CD29+ stromal-like cells

(2009) Hyun Sook Hong et al.   NATURE MEDICINE

Substance P accelerates intestinal tissue regeneration after γ-irradiation-induced damage

(2009) Mi-Hyun Kang et al.   WOUND REPAIR AND REGENERATION

Cartilage damage pattern in relation to subchondral plate thickness in a collagenase-induced model of osteoarthritis

(2007) S.M. Botter et al.   OSTEOARTHRITIS AND CARTILAGE