Role of GM-CSF in regulating metabolism and mitochondrial functions critical to macrophage proliferation

Asymmetrically Segregated Mitochondria Provide Cellular Memory of Hematopoietic Stem Cell Replicative History and Drive HSC Attrition

(2020) Ashwini Hinge et al.   Cell Stem Cell

Sleep fragmentation increases blood pressure and is associated with alterations in the gut microbiome and fecal metabolome in rats

(2020) Katherine A. Maki et al.   PHYSIOLOGICAL GENOMICS

Increased Pulmonary GM-CSF Causes Alveolar Macrophage Accumulation: Mechanistic Implications for Desquamative Interstitial Pneumonitis

(2019) Takuji Suzuki et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Long-Term Safety and Efficacy of Gene-Pulmonary Macrophage Transplantation Therapy of PAP in Csf2ra−/− Mice

(2019) Paritha Arumugam et al.   MOLECULAR THERAPY

Macrophage colony-stimulating factor increases hepatic macrophage content, liver growth, and lipid accumulation in neonatal rats

(2018) Clare Pridans et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

PPARγ Regulates Mitochondrial Structure and Function and Human Pulmonary Artery Smooth Muscle Cell Proliferation

(2018) Samantha M. Yeligar et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Hematopoietic stem cell fate through metabolic control

(2018) Kyoko Ito et al.   EXPERIMENTAL HEMATOLOGY

Acetate Production from Glucose and Coupling to Mitochondrial Metabolism in Mammals

(2018) Xiaojing Liu et al.   CELL

Taurine: A Regulator of Cellular Redox-Homeostasis and Skeletal Muscle Function

(2018) Ulrike Seidel et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Neuropeptide FF increases M2 activation and self-renewal of adipose tissue macrophages

(2017) Syed F. Hassnain Waqas et al.   JOURNAL OF CLINICAL INVESTIGATION

Overexpression of the human DEK oncogene reprograms cellular metabolism and promotes glycolysis

(2017) Marie C. Matrka et al.   PLoS One

Targeting cholesterol homeostasis in lung diseases

(2017) Anthony Sallese et al.   Scientific Reports

New insights into the multidimensional concept of macrophage ontogeny, activation and function

(2016) Florent Ginhoux et al.   NATURE IMMUNOLOGY

Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells

(2016) E. L. Soucie et al.   SCIENCE

Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance

(2016) K. Ito et al.   SCIENCE

Adiponectin Enhances Cold-Induced Browning of Subcutaneous Adipose Tissue via Promoting M2 Macrophage Proliferation

(2015) Xiaoyan Hui et al.   Cell Metabolism

Retinoid X receptors orchestrate osteoclast differentiation and postnatal bone remodeling

(2015) María P. Menéndez-Gutiérrez et al.   JOURNAL OF CLINICAL INVESTIGATION

Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness

(2015) P. Katajisto et al.   SCIENCE

Highly proliferative primitive fetal liver hematopoietic stem cells are fueled by oxidative metabolic pathways

(2015) Javed K. Manesia et al.   Stem Cell Research

L-Arginine Depletion Blunts Antitumor T-cell Responses by Inducing Myeloid-Derived Suppressor Cells

(2014) M. Fletcher et al.   CANCER RESEARCH

GM-CSF Induces Cyclin D1 Expression and Proliferation of Endothelial Progenitor Cells via PI3K and MAPK Signaling

(2014) Chaolin Qiu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

ATP/ADP ratio, the missed connection between mitochondria and the Warburg effect

(2014) Eduardo N. Maldonado et al.   MITOCHONDRION

Pulmonary macrophage transplantation therapy

(2014) Takuji Suzuki et al.   NATURE

Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages

(2014) Stanley Ching-Cheng Huang et al.   NATURE IMMUNOLOGY

Metabolic requirements for the maintenance of self-renewing stem cells

(2014) Keisuke Ito et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

Beyond Stem Cells: Self-Renewal of Differentiated Macrophages

(2013) M. H. Sieweke et al.   SCIENCE

Peroxisome Proliferator-Activated-γ Coactivator-1α–Mediated Mitochondrial Biogenesis Is Important for Hematopoietic Recovery in Response to Stress

(2013) Sunanda Basu et al.   STEM CELLS AND DEVELOPMENT

PGC1  and mitochondrial metabolism - emerging concepts and relevance in ageing and neurodegenerative disorders

(2012) S. Austin et al.   JOURNAL OF CELL SCIENCE

IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia

(2012) Yaming Wang et al.   NATURE IMMUNOLOGY

A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance

(2012) Keisuke Ito et al.   NATURE MEDICINE

AMP-activated protein kinase--an energy sensor that regulates all aspects of cell function

(2011) D. G. Hardie   GENES & DEVELOPMENT

Human IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lung

(2011) T. Willinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hereditary Pulmonary Alveolar Proteinosis

(2010) Takuji Suzuki et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Patient-derived Granulocyte/Macrophage Colony–Stimulating Factor Autoantibodies Reproduce Pulmonary Alveolar Proteinosis in Nonhuman Primates

(2010) Takuro Sakagami et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Interdependence of AMPK and SIRT1 for Metabolic Adaptation to Fasting and Exercise in Skeletal Muscle

(2010) Carles Cantó et al.   Cell Metabolism

Hereditary pulmonary alveolar proteinosis caused by recessive CSF2RB mutations

(2010) T. Suzuki et al.   EUROPEAN RESPIRATORY JOURNAL

Hispidulin Potently Inhibits Human Glioblastoma Multiforme Cells through Activation of AMP-Activated Protein Kinase (AMPK)

(2010) Ying-Chao Lin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Adult-onset hereditary pulmonary alveolar proteinosis caused by a single-base deletion in CSF2RB

(2010) T. Tanaka et al.   JOURNAL OF MEDICAL GENETICS

Evaluation of 13C isotopic tracers for metabolic flux analysis in mammalian cells

(2009) Christian M. Metallo et al.   JOURNAL OF BIOTECHNOLOGY

The Krebs cycle meets the cell cycle: Mitochondria and the G1-S transition

(2009) T. Finkel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase

(2009) K. Mitra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MafB/c-Maf Deficiency Enables Self-Renewal of Differentiated Functional Macrophages

(2009) A. Aziz et al.   SCIENCE

Granulocyte/macrophage-colony-stimulating factor autoantibodies and myeloid cell immune functions in healthy subjects

(2008) K. Uchida et al.   BLOOD

C-terminal Phosphorylation of LKB1 Is Not Required for Regulation of AMP-activated Protein Kinase, BRSK1, BRSK2, or Cell Cycle Arrest

(2008) Sarah Fogarty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Familial pulmonary alveolar proteinosis caused by mutations inCSF2RA

(2008) Takuji Suzuki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Metabolite identification via the Madison Metabolomics Consortium Database

(2008) Qiu Cui et al.   NATURE BIOTECHNOLOGY