The role of Sirtuin 2 in sustaining functional integrity of the liver

SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways

(2021) Yasser Majeed et al.   Scientific Reports

Liver sinusoidal endothelial cells — gatekeepers of hepatic immunity

(2018) Shishir Shetty et al.   Nature Reviews Gastroenterology & Hepatology

SIRT2 is required for efficient reprogramming of mouse embryonic fibroblasts toward pluripotency

(2018) Ah-Young Kim et al.   Cell Death & Disease

The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases

(2017) Naga Chalasani et al.   HEPATOLOGY

Cellular senescence drives age-dependent hepatic steatosis

(2017) Mikolaj Ogrodnik et al.   Nature Communications

Senescence and cell death in chronic liver injury: roles and mechanisms underlying hepatocarcinogenesis

(2017) Mengchao Xiao et al.   Oncotarget

SIRT1 suppresses adipogenesis by activating Wnt/β-catenin signaling in vivo and in vitro

(2016) Yuanfei Zhou et al.   Oncotarget

Contemporary Assessment of Hepatic Fibrosis

(2015) Alan Bonder et al.   Clinics in Liver Disease

Acetylation of TUG Protein Promotes the Accumulation of GLUT4 Glucose Transporters in an Insulin-responsive Intracellular Compartment

(2015) Jonathan P. Belman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Liver sinusoidal endothelial cells (LSECs) function and NAFLD; NO-based therapy targeted to the liver

(2015) Edyta Maslak et al.   Pharmacological Reports

Emerging Role of Sirtuin 2 in the Regulation of Mammalian Metabolism

(2015) Pedro Gomes et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The senescent hepatocyte gene signature in chronic liver disease

(2014) Aloysious Aravinthan et al.   EXPERIMENTAL GERONTOLOGY

Sirt2 Deacetylase Is a Novel AKT Binding Partner Critical for AKT Activation by Insulin

(2014) Gopalakrishnan Ramakrishnan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Formation of Fenestrae in Murine Liver Sinusoids Depends on Plasmalemma Vesicle-Associated Protein and Is Required for Lipoprotein Passage

(2014) Leonie Herrnberger et al.   PLoS One

SIRT2 overexpression in hepatocellular carcinoma mediates epithelial to mesenchymal transition by protein kinase B/glycogen synthase kinase-3β/β-catenin signaling

(2013) Juan Chen et al.   HEPATOLOGY

Exercise, GLUT4, and Skeletal Muscle Glucose Uptake

(2013) Erik A. Richter et al.   PHYSIOLOGICAL REVIEWS

Hepatocyte Expression of the Senescence Marker p21 Is Linked to Fibrosis and an Adverse Liver-Related Outcome in Alcohol-Related Liver Disease

(2013) Aloysious Aravinthan et al.   PLoS One

Hepatic Fatty Acid Trafficking: Multiple Forks in the Road

(2013) Douglas G. Mashek   Advances in Nutrition

Skeletal Muscle Insulin Resistance Promotes Increased Hepatic De Novo Lipogenesis, Hyperlipidemia, and Hepatic Steatosis in the Elderly

(2012) C. Flannery et al.   DIABETES

Hepatocyte senescence predicts progression in non-alcohol-related fatty liver disease

(2012) Aloysious Aravinthan et al.   JOURNAL OF HEPATOLOGY

Aquaporin-9 Protein Is the Primary Route of Hepatocyte Glycerol Uptake for Glycerol Gluconeogenesis in Mice

(2011) Sabina Jelen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxisome proliferator activated receptor α (PPARα) and PPAR gamma coactivator (PGC-1α) induce carnitine palmitoyltransferase IA (CPT-1A) via independent gene elements

(2010) Shulan Song et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The Role of Sirtuins in the Control of Metabolic Homeostasis

(2009) Jiujiu Yu et al.   Annals of the New York Academy of Sciences

Sinusoidal endothelial cells prevent rat stellate cell activation and promote reversion to quiescence

(2008) Laurie D. DeLeve et al.   HEPATOLOGY

Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)

(2008) G MUSSO et al.   PROGRESS IN LIPID RESEARCH