标题
Targeting the NOTCH1-MYC-CD44 axis in leukemia-initiating cells in T-ALL
作者
关键词
-
出版物
LEUKEMIA
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-02-16
DOI
10.1038/s41375-022-01516-1
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Large-scale circular RNA deregulation in T-ALL: unlocking unique ectopic expression of molecular subtypes
- (2020) Alessia Buratin et al. Blood Advances
- BETP degradation simultaneously targets acute myelogenous leukemic stem cells and the microenvironment
- (2019) Sujan Piya et al. JOURNAL OF CLINICAL INVESTIGATION
- A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity
- (2019) Sajid Khan et al. NATURE MEDICINE
- Leukemia reconstitution in vivo is driven by cells in early cell cycle and low metabolic state
- (2018) Luca Trentin et al. HAEMATOLOGICA
- The NOTCH1/CD44 axis drives pathogenesis in a T cell acute lymphoblastic leukemia model
- (2018) Marina García-Peydró et al. JOURNAL OF CLINICAL INVESTIGATION
- The subclonal complexity of STIL-TAL1+ T-cell acute lymphoblastic leukaemia
- (2018) Caroline L Furness et al. LEUKEMIA
- Leukemia reconstitution in vivo is driven by cells in early cell cycle and low metabolic state
- (2018) Luca Trentin et al. HAEMATOLOGICA
- Regulation of PI3K signaling in T-cell acute lymphoblastic leukemia: a novel PTEN/Ikaros/miR-26b mechanism reveals a critical targetable role for PIK3CD
- (2017) T Yuan et al. LEUKEMIA
- BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment
- (2017) Georg E. Winter et al. MOLECULAR CELL
- T-cell acute lymphoblastic leukemia
- (2016) E. A. Raetz et al. Hematology-American Society of Hematology Education Program
- Bone marrow stem cells: current and emerging concepts
- (2015) Simón Méndez-Ferrer et al. Annals of the New York Academy of Sciences
- Leukemia stem cells in T-ALL require active Hif1α and Wnt signaling
- (2015) Vincenzo Giambra et al. BLOOD
- CXCR4 Is Required for Leukemia-Initiating Cell Activity in T Cell Acute Lymphoblastic Leukemia
- (2015) Diana Passaro et al. CANCER CELL
- Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4
- (2015) Jing Lu et al. CHEMISTRY & BIOLOGY
- Stem Cell Hierarchy and Clonal Evolution in Acute Lymphoblastic Leukemia
- (2015) Fabian Lang et al. Stem Cells International
- Targeting the MYC and PI3K Pathways Eliminates Leukemia-Initiating Cells in T-cell Acute Lymphoblastic Leukemia
- (2014) S. Schubbert et al. CANCER RESEARCH
- An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia
- (2014) Birgit Knoechel et al. NATURE GENETICS
- A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia
- (2014) Daniel Herranz et al. NATURE MEDICINE
- Targeting bromodomains: epigenetic readers of lysine acetylation
- (2014) Panagis Filippakopoulos et al. NATURE REVIEWS DRUG DISCOVERY
- Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers
- (2013) Jakob Lovén et al. CELL
- The Ubiquitin Ligase FBXW7 Modulates Leukemia-Initiating Cell Activity by Regulating MYC Stability
- (2013) Bryan King et al. CELL
- BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells
- (2013) Eleni D. Lagadinou et al. Cell Stem Cell
- CXCR4 downregulation of let-7a drives chemoresistance in acute myeloid leukemia
- (2013) Ye Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- A review on CXCR4/CXCL12 axis in oncology: No place to hide
- (2012) Urszula M. Domanska et al. EUROPEAN JOURNAL OF CANCER
- NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-θ and reactive oxygen species
- (2012) Vincenzo Giambra et al. NATURE MEDICINE
- CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc− and Thereby Promotes Tumor Growth
- (2011) Takatsugu Ishimoto et al. CANCER CELL
- BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
- (2011) Jake E. Delmore et al. CELL
- Leukemia Stem Cells and Microenvironment: Biology and Therapeutic Targeting
- (2011) Marina Y. Konopleva et al. JOURNAL OF CLINICAL ONCOLOGY
- Expression of CD34 and CD7 on human T-cell acute lymphoblastic leukemia discriminates functionally heterogeneous cell populations
- (2011) B Gerby et al. LEUKEMIA
- RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
- (2011) Johannes Zuber et al. NATURE
- Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
- (2011) Mark A. Dawson et al. NATURE
- Inactivation of LEF1 in T-cell acute lymphoblastic leukemia
- (2010) A. Gutierrez et al. BLOOD
- Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss
- (2009) H. Medyouf et al. BLOOD
- The role of NOTCH1 signaling in T-ALL
- (2009) A. A. Ferrando Hematology-American Society of Hematology Education Program
- NOTCH is a key regulator of human T-cell acute leukemia initiating cell activity
- (2008) F. Armstrong et al. BLOOD
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