Using Machine Learning to Identify Metabolomic Signatures of Pediatric Chronic Kidney Disease Etiology

Genome-wide association study of serum metabolites in the African American Study of Kidney Disease and Hypertension

(2021) Shengyuan Luo et al.   KIDNEY INTERNATIONAL

Metabolite Biomarkers of CKD Progression in Children

(2021) Michelle R. Denburg et al.   Clinical Journal of the American Society of Nephrology

A metabolome and microbiome wide association study of healthy eating index points to the mechanisms linking dietary pattern and metabolic status

(2021) Minoo Bagheri et al.   EUROPEAN JOURNAL OF NUTRITION

The advantages of the Matthews correlation coefficient (MCC) over F1 score and accuracy in binary classification evaluation

(2020) Davide Chicco et al.   BMC GENOMICS

Microbial Imidazole Propionate Affects Responses to Metformin through p38γ-Dependent Inhibitory AMPK Phosphorylation

(2020) Ara Koh et al.   Cell Metabolism

NAT8 Variants, N-Acetylated Amino Acids, and Progression of CKD

(2020) Shengyuan Luo et al.   Clinical Journal of the American Society of Nephrology

Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology

(2020) Antonio Molinaro et al.   Nature Communications

Blood Microbiome Profile in CKD

(2019) Neal B. Shah et al.   Clinical Journal of the American Society of Nephrology

Circulating levels of the anti-oxidant indoleproprionic acid are associated with higher gut microbiome diversity

(2019) Cristina Menni et al.   Gut Microbes

Lactobacillus reuteri DSM 17938 feeding of healthy newborn mice regulates immune responses while modulating gut microbiota and boosting beneficial metabolites

(2019) Yuying Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Regulation of the amount of ceramide-1-phosphate synthesized in differentiated human podocytes

(2019) Shamroop Kumar Mallela et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Association of cholesterol efflux capacity with plasmalogen levels of high-density lipoprotein: A cross-sectional study in chronic kidney disease patients

(2018) Ryouta Maeba et al.   ATHEROSCLEROSIS

Recommending plant taxa for supporting on-site species identification

(2018) Hans Christian Wittich et al.   BMC BIOINFORMATICS

Microbiome and Cardiovascular Disease in CKD

(2018) Anna Jovanovich et al.   Clinical Journal of the American Society of Nephrology

Serum metabolites are associated with all-cause mortality in chronic kidney disease

(2018) Jiun-Ruey Hu et al.   KIDNEY INTERNATIONAL

Metabolomic profiling to improve glomerular filtration rate estimation: a proof-of-concept study

(2018) Josef Coresh et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

EGBMMDA: Extreme Gradient Boosting Machine for MiRNA-Disease Association prediction

(2018) Xing Chen et al.   Cell Death & Disease

Variability of Two Metabolomic Platforms in CKD

(2018) Eugene P. Rhee et al.   Clinical Journal of the American Society of Nephrology

Translational Aspects of Sphingolipid Metabolism in Renal Disorders

(2017) Alaa Abou Daher et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Urinary excretion of sphingomyelinase phosphodiesterase acid-like 3b in children with intractable nephrotic syndrome

(2017) Shojiro Watanabe et al.   PEDIATRICS INTERNATIONAL

Metabolomics of Chronic Kidney Disease Progression: A Case-Control Analysis in the Chronic Renal Insufficiency Cohort Study

(2016) Eugene P. Rhee et al.   AMERICAN JOURNAL OF NEPHROLOGY

A random forest guided tour

(2016) Gérard Biau et al.   TEST

Conserved Metabolic Changes in Nondiabetic and Type 2 Diabetic Bariatric Surgery Patients: Global Metabolomic Pilot Study

(2016) Konrad Sarosiek et al.   Journal of Diabetes Research

A random forest guided tour

(2016) Gérard Biau et al.   TEST

Gut microbiome in chronic kidney disease

(2015) Maria R. Wing et al.   EXPERIMENTAL PHYSIOLOGY

Metabolomics in pediatric nephrology: emerging concepts

(2014) Mina H. Hanna et al.   PEDIATRIC NEPHROLOGY

Podocyte Pathology and Nephropathy – Sphingolipids in Glomerular Diseases

(2014) Sandra Merscher et al.   Frontiers in Endocrinology

CKiD (CKD in Children) Prospective Cohort Study: A Review of Current Findings

(2012) Cynthia J. Wong et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Functions of plasmalogen lipids in health and disease

(2012) Nancy E. Braverman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Application of 1H NMR metabonomics in predicting renal function recoverability after the relief of obstructive uropathy in adult patients

(2012) Baijun Dong et al.   CLINICAL BIOCHEMISTRY

Anti-apoptotic and anti-oxidative mechanisms of minocycline against sphingomyelinase/ceramide neurotoxicity: implication in Alzheimer's disease and cerebral ischemia

(2012) Shang-Der Chen et al.   FREE RADICAL RESEARCH

Oral bioavailability of the ether lipid plasmalogen precursor, PPI-1011, in the rabbit: a new therapeutic strategy for Alzheimer's disease

(2011) Paul L Wood et al.   Lipids in Health and Disease

In vitro and in vivo plasmalogen replacement evaluations in rhizomelic chrondrodysplasia punctata and Pelizaeus-Merzbacher disease using PPI-1011, an ether lipid plasmalogen precursor

(2011) Paul L Wood et al.   Lipids in Health and Disease

Epidemiology of chronic kidney disease in children

(2011) Jérôme Harambat et al.   PEDIATRIC NEPHROLOGY

Rituximab Targets Podocytes in Recurrent Focal Segmental Glomerulosclerosis

(2011) A. Fornoni et al.   Science Translational Medicine

Role of triglyceride-rich lipoproteins in diabetic nephropathy

(2010) John C. Rutledge et al.   Nature Reviews Nephrology

Organization of GC/MS and LC/MS metabolomics data into chemical libraries

(2010) Corey D DeHaven et al.   Journal of Cheminformatics

Integrated, Nontargeted Ultrahigh Performance Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry Platform for the Identification and Relative Quantification of the Small-Molecule Complement of Biological Systems

(2009) Anne M. Evans et al.   ANALYTICAL CHEMISTRY

New Equations to Estimate GFR in Children with CKD

(2009) G. J. Schwartz et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY