Bergenin ameliorates diabetic nephropathy in rats via suppressing renal inflammation and TGF-β1-Smads pathway

microRNA-34a inhibits epithelial mesenchymal transition in human cholangiocarcinoma by targeting Smad4 through transforming growth factor-beta/Smad pathway

(2015) Pengfei Qiao et al.   BMC CANCER

Combination of Active Components of Xiexin Decoction Ameliorates Renal Fibrosis Through the Inhibition of NF-κB and TGF-β1/Smad Pathways in db/db Diabetic Mice

(2015) Jia-Sheng Wu et al.   PLoS One

Ruscogenin ameliorates diabetic nephropathy by its anti-inflammatory and anti-fibrotic effects in streptozotocin-induced diabetic rat

(2014) Hung-Jen Lu et al.   BMC Complementary and Alternative Medicine

Amelioration of streptozotocin-induced diabetic nephropathy by melatonin, quercetin, and resveratrol in rats

(2014) H Elbe et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Bergenin Plays an Anti-Inflammatory Role via the Modulation of MAPK and NF-κB Signaling Pathways in a Mouse Model of LPS-Induced Mastitis

(2014) Xue-jiao Gao et al.   INFLAMMATION

Beneficial effects of phlorizin on diabetic nephropathy in diabetic db/db mice

(2014) Fei Pei et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Pyrano-isochromanones as IL-6 Inhibitors: Synthesis, in Vitro and in Vivo Antiarthritic Activity

(2014) Shreyans K. Jain et al.   JOURNAL OF MEDICINAL CHEMISTRY

Chronic inhibition of cyclic guanosine monophosphate-specific phosphodiesterase 5 prevented cardiac fibrosis through inhibition of transforming growth factor β-induced Smad signaling

(2014) Wei Gong et al.   Frontiers of Medicine

Pentamethylquercetin ameliorates fibrosis in diabetic Goto-Kakizaki rat kidneys and mesangial cells with suppression of TGF-β/Smads signaling

(2013) Xin Xin et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Type 2 antidiabetic activity of bergenin from the roots of Caesalpinia digyna Rottler

(2011) Rajesh Kumar et al.   FITOTERAPIA

The contribution of hypertension to diabetic nephropathy and retinopathy: the role of inflammation and oxidative stress

(2011) José Butori Lopes de Faria et al.   HYPERTENSION RESEARCH

Effects of Silencing Transforming Growth Factor-β1 by RNA Interference Plasmid on Rat Renal Allograft Fibrosis Using Smads Pathway

(2011) Zhikang Yin et al.   UROLOGY

Relationship between Oxidative Stress and Inflammatory Cytokines in Diabetic Nephropathy

(2010) Ahmed A. Elmarakby et al.   Cardiovascular Therapeutics

The Protective Role of Smad7 in Diabetic Kidney Disease: Mechanism and Therapeutic Potential

(2010) H. Y. Chen et al.   DIABETES

Tumor Necrosis Factor (TNF-α) and C-reactive Protein (CRP) are Positively Associated with the Risk of Chronic Kidney Disease in Patients with Type 2 Diabetes

(2010) Eun-Sil Yeo et al.   YONSEI MEDICAL JOURNAL

Regulation of TGF-  signaling by Smad7

(2009) X. Yan et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Bone Morphogenetic Protein-2 Antagonizes Renal Interstitial Fibrosis by Promoting Catabolism of Type I Transforming Growth Factor-β Receptors

(2008) Yu-Lin Yang et al.   ENDOCRINOLOGY

The Role of Inflammatory Cytokines in Diabetic Nephropathy

(2008) J. F. Navarro-Gonzalez et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY