Immunosuppressive evidence ofTityus serrulatustoxins Ts6 and Ts15: insights of a novel K+channel pattern in T cells

Isolation and characterization of Ts19 Fragment II, a new long-chain potassium channel toxin from Tityus serrulatus venom

(2016) Felipe Augusto Cerni et al.   PEPTIDES

Electrophysiological characterization of the first Tityus serrulatus alpha-like toxin, Ts5: Evidence of a pro-inflammatory toxin on macrophages

(2015) Manuela B. Pucca et al.   BIOCHIMIE

A gamut of undiscovered electrophysiological effects produced by Tityus serrulatus toxin 1 on NaV-type isoforms

(2015) Steve Peigneur et al.   NEUROPHARMACOLOGY

Scorpion venom components as potential candidates for drug development

(2015) Ernesto Ortiz et al.   TOXICON

Revealing the Function and the Structural Model of Ts4: Insights into the “Non-Toxic” Toxin from Tityus serrulatus Venom

(2015) Manuela Pucca et al.   Toxins

Physiological Role of Kv1.3 Channel in T Lymphocyte Cell Investigated Quantitatively by Kinetic Modeling

(2014) Panpan Hou et al.   PLoS One

A potent and Kv1.3-selective analogue of the scorpion toxin HsTX1 as a potential therapeutic for autoimmune diseases

(2014) M. Harunur Rashid et al.   Scientific Reports

Electrophysiological Characterization of Ts6 and Ts7, K+ Channel Toxins Isolated through an Improved Tityus serrulatus Venom Purification Procedure

(2014) Felipe Cerni et al.   Toxins

Kv1.3 blockers ameliorate allergic contact dermatitis by preferentially suppressing effector memory T cells in a rat model

(2013) A. Ueyama et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Modulation of KV1.3 channels by protein kinase A I in T lymphocytes is mediated by the disc large 1-tyrosine kinase Lck complex

(2012) Zerrin Kuras et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Investigation of the relationship between the structure and function of Ts2, a neurotoxin from Tityus serrulatus venom

(2012) Camila T. Cologna et al.   FEBS Journal

Purification and characterization of Ts15, the first member of a new α-KTX subfamily from the venom of the Brazilian scorpion Tityus serrulatus

(2011) C.T. Cologna et al.   TOXICON

Spiro azepane-oxazolidinones as Kv1.3 potassium channel blockers: WO2010066840

(2010) Heike Wulff   EXPERT OPINION ON THERAPEUTIC PATENTS

Differential calcium signaling and Kv1.3 trafficking to the immunological synapse in systemic lupus erythematosus

(2009) Stella A. Nicolaou et al.   CELL CALCIUM

Voltage-gated potassium channels as therapeutic targets

(2009) Heike Wulff et al.   NATURE REVIEWS DRUG DISCOVERY