Piezo 1 is involved in intraocular pressure regulation

Mechanical stretch induces Ca2+ influx and extracellular release of PGE2 through Piezo1 activation in trabecular meshwork cells

(2021) Takatoshi Uchida et al.   Scientific Reports

Piezo1 channels mediate trabecular meshwork mechanotransduction and promote aqueous fluid outflow

(2020) Oleg Yarishkin et al.   JOURNAL OF PHYSIOLOGY-LONDON

Agonist-induced Piezo1 activation suppresses migration of transformed fibroblasts

(2019) Vladislav I. Chubinskiy-Nadezhdin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Temozolomide has anti-tumor effects through the phosphorylation of cPLA2 on glioblastoma cells

(2019) Shohei Tsuji et al.   BRAIN RESEARCH

Role of Fibronectin in Primary Open Angle Glaucoma

(2019) Jennifer A. Faralli et al.   Cells

Piezo channel plays a part in retinal ganglion cell damage

(2019) Wataru Morozumi et al.   EXPERIMENTAL EYE RESEARCH

Glaucomatous cell derived matrices differentially modulate non-glaucomatous trabecular meshwork cellular behavior

(2018) Vijay Krishna Raghunathan et al.   Acta Biomaterialia

Consensus recommendations for trabecular meshwork cell isolation, characterization and culture

(2018) Kate E. Keller et al.   EXPERIMENTAL EYE RESEARCH

Mechanical regulation of stem-cell differentiation by the stretch-activated Piezo channel

(2018) Li He et al.   NATURE

Probing the gating mechanism of the mechanosensitive channel Piezo1 with the small molecule Yoda1

(2018) Jerome J. Lacroix et al.   Nature Communications

Enantiomeric Aβ peptides inhibit the fluid shear stress response of PIEZO1

(2018) Mohammad M. Maneshi et al.   Scientific Reports

Piezo1 mediates angiogenesis through activation of MT1-MMP signaling

(2018) Hojin Kang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Impaired Cerebellar Development in Mice Overexpressing VGF

(2018) Takahiro Mizoguchi et al.   NEUROCHEMICAL RESEARCH

Mechanical stretch triggers rapid epithelial cell division through Piezo1

(2017) S. A. Gudipaty et al.   NATURE

Aqueous outflow - A continuum from trabecular meshwork to episcleral veins

(2017) Teresia Carreon et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Touch, Tension, and Transduction – The Function and Regulation of Piezo Ion Channels

(2017) Jason Wu et al.   TRENDS IN BIOCHEMICAL SCIENCES

Increased synthesis and deposition of extracellular matrix proteins leads to endoplasmic reticulum stress in the trabecular meshwork

(2017) Ramesh B. Kasetti et al.   Scientific Reports

Piezo type mechanosensitive ion channel component 1 functions as a regulator of the cell fate determination of mesenchymal stem cells

(2017) Asuna Sugimoto et al.   Scientific Reports

Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release

(2016) ShengPeng Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Piezo2 is required for Merkel-cell mechanotransduction

(2014) Seung-Hyun Woo et al.   NATURE

Mechanotransduction Channels of the Trabecular Meshwork

(2013) Vu T. Tran et al.   CURRENT EYE RESEARCH

Senescent Phenotype of Trabecular Meshwork Cells Displays Biomarkers in Primary Open-Angle Glaucoma

(2012) M.A. Babizhayev et al.   CURRENT MOLECULAR MEDICINE

Activation of the BKCa Channel Increases Outflow Facility and Decreases Trabecular Meshwork Cell Volume

(2009) William M. Dismuke et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Primary Open-Angle Glaucoma

(2009) Young H. Kwon et al.   NEW ENGLAND JOURNAL OF MEDICINE

NO-induced regulation of human trabecular meshwork cell volume and aqueous humor outflow facility involve the BKCa ion channel

(2008) William M. Dismuke et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Extracellular matrix in the trabecular meshwork

(2008) Ted S. Acott et al.   EXPERIMENTAL EYE RESEARCH

Structural changes of the trabecular meshwork in different kinds of glaucoma

(2008) Ozan-Yüksel Tektas et al.   EXPERIMENTAL EYE RESEARCH