Quantitative analysis of human brain microdialysate for target site pharmacokinetics of major anesthetics ketamine, midazolam and propofol

Cerebrospinal fluid penetration of targeted therapeutics in pediatric brain tumor patients

(2020) Armin Sebastian Guntner et al.   Acta Neuropathologica Communications

Development of a highly sensitive GC-MS method preceded by solid-phase microextraction for the analysis of propofol in low-volume cerebral microdialysate samples

(2019) Armin Sebastian Guntner et al.   JOURNAL OF SEPARATION SCIENCE

Collision cross sections obtained with ion mobility mass spectrometry as new descriptor to predict blood-brain barrier permeation by drugs

(2019) Armin Sebastian Guntner et al.   Scientific Reports

Clinical Pharmacokinetics and Pharmacodynamics of Propofol

(2018) Marko M. Sahinovic et al.   CLINICAL PHARMACOKINETICS

An ultra-sensitive LC–MS/MS method to determine midazolam levels in human plasma: development, validation and application to a clinical study

(2017) Mu Chen et al.   Bioanalysis

Ketamine: A Review of Clinical Pharmacokinetics and Pharmacodynamics in Anesthesia and Pain Therapy

(2016) Marko A. Peltoniemi et al.   CLINICAL PHARMACOKINETICS

Illegal use patterns, side effects, and analytical methods of ketamine

(2016) Eunyoung Han et al.   FORENSIC SCIENCE INTERNATIONAL

A Review on Microdialysis Calibration Methods: the Theory and Current Related Efforts

(2016) Chun Min Kho et al.   MOLECULAR NEUROBIOLOGY

In Vitro Models of the Blood–Brain Barrier for the Study of Drug Delivery to the Brain

(2014) Imola Wilhelm et al.   MOLECULAR PHARMACEUTICS

A study of analytical methods for the determination of propofol in blood

(2013) Eunyoung Han   ARCHIVES OF PHARMACAL RESEARCH

Demystifying Brain Penetration in Central Nervous System Drug Discovery

(2012) Li Di et al.   JOURNAL OF MEDICINAL CHEMISTRY

QSAR Analysis of Blood–Brain Distribution: The Influence of Plasma and Brain Tissue Binding

(2011) Kiril Lanevskij et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Cerebral Perfusion Pressure Thresholds for Brain Tissue Hypoxia and Metabolic Crisis After Poor-Grade Subarachnoid Hemorrhage

(2011) J. Michael Schmidt et al.   STROKE

Addressing Central Nervous System (CNS) Penetration in Drug Discovery: Basics and Implications of the Evolving New Concept

(2009) Andreas Reichel   CHEMISTRY & BIODIVERSITY

CSF as a Surrogate for Assessing CNS Exposure: An Industrial Perspective

(2008) Jiunn Lin   CURRENT DRUG METABOLISM