HMGB1 mediates cognitive impairment caused by the NLRP3 inflammasome in the late stage of traumatic brain injury

Glycyrrhizic acid as an adjunctive treatment for depression through anti-inflammation: A randomized placebo-controlled clinical trial

(2020) Zhi-Yong Cao et al.   JOURNAL OF AFFECTIVE DISORDERS

Microglial depletion with CSF1R inhibitor during chronic phase of experimental traumatic brain injury reduces neurodegeneration and neurological deficits

(2020) Rebecca J. Henry et al.   JOURNAL OF NEUROSCIENCE

Salidroside ameliorates Parkinson's disease by inhibiting NLRP3-dependent pyroptosis

(2020) Xue Zhang et al.   Aging-US

Visceral adipose NLRP3 impairs cognition in obesity via IL-1R1 on CX3CR1+ cells

(2020) De-Huang Guo et al.   JOURNAL OF CLINICAL INVESTIGATION

The NLRP3 inflammasome in traumatic brain injury: potential as a biomarker and therapeutic target

(2020) William T. O’Brien et al.   Journal of Neuroinflammation

High mobility group box-1 mediates hippocampal inflammation and contributes to cognitive deficits in high-fat high-fructose diet-induced obese rats

(2019) Min Yu et al.   BRAIN BEHAVIOR AND IMMUNITY

Targeting high-mobility group box protein 1 (HMGB1) in pediatric traumatic brain injury: Chronic neuroinflammatory, behavioral, and epileptogenic consequences

(2019) Kyria M. Webster et al.   EXPERIMENTAL NEUROLOGY

NLRP3 inflammasome activation drives tau pathology

(2019) Christina Ising et al.   NATURE

Selective NLRP3 inflammasome inhibitor reduces neuroinflammation and improves long-term neurological outcomes in a murine model of traumatic brain injury

(2018) Xin Xu et al.   NEUROBIOLOGY OF DISEASE

Glycyrrhizin Protects Mice Against Experimental Autoimmune Encephalomyelitis by Inhibiting High-Mobility Group Box 1 (HMGB1) Expression and Neuronal HMGB1 Release

(2018) Yan Sun et al.   Frontiers in Immunology

Inflammasome signalling in brain function and neurodegenerative disease

(2018) Michael T. Heneka et al.   NATURE REVIEWS NEUROSCIENCE

HMGB1: A Common Biomarker and Potential Target for TBI, Neuroinflammation, Epilepsy, and Cognitive Dysfunction

(2018) Yam Nath Paudel et al.   Frontiers in Neuroscience

Cerebrospinal Fluid NLRP3 is Increased After Severe Traumatic Brain Injury in Infants and Children

(2017) Jessica S. Wallisch et al.   Neurocritical Care

Adenosine A2A receptor inactivation alleviates early-onset cognitive dysfunction after traumatic brain injury involving an inhibition of tau hyperphosphorylation

(2017) Z-A Zhao et al.   Translational Psychiatry

Lack of the Nlrp3 Inflammasome Improves Mice Recovery Following Traumatic Brain Injury

(2017) Natasha Irrera et al.   Frontiers in Pharmacology

Stress sounds the alarmin: The role of the danger-associated molecular pattern HMGB1 in stress-induced neuroinflammatory priming

(2015) Matthew G. Frank et al.   BRAIN BEHAVIOR AND IMMUNITY

Presynaptic adenosine A2Areceptors dampen cannabinoid CB1receptor-mediated inhibition of corticostriatal glutamatergic transmission

(2015) S G Ferreira et al.   BRITISH JOURNAL OF PHARMACOLOGY

Blonanserin Ameliorates Phencyclidine-Induced Visual-Recognition Memory Deficits: the Complex Mechanism of Blonanserin Action Involving D3-5-HT2A and D1-NMDA Receptors in the mPFC

(2014) Hirotake Hida et al.   NEUROPSYCHOPHARMACOLOGY

Plasma glutamate–modulated interaction of A2AR and mGluR5 on BMDCs aggravates traumatic brain injury–induced acute lung injury

(2013) Shuang-Shuang Dai et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The neuron-specific chromatin regulatory subunit BAF53b is necessary for synaptic plasticity and memory

(2013) Annie Vogel-Ciernia et al.   NATURE NEUROSCIENCE

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

Inflammation after trauma: Microglial activation and traumatic brain injury

(2011) Anil F. Ramlackhansingh et al.   ANNALS OF NEUROLOGY

Enhanced role of adenosine A2A receptors in the modulation of LTP in the rat hippocampus upon ageing

(2011) Ana R. Costenla et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

High-mobility group box-1 impairs memory in mice through both toll-like receptor 4 and Receptor for Advanced Glycation End Products

(2011) Andréy Mazarati et al.   EXPERIMENTAL NEUROLOGY

The Human Immunodeficiency Virus Coat Protein gp120 Promotes Forward Trafficking and Surface Clustering of NMDA Receptors in Membrane Microdomains

(2011) H. Xu et al.   JOURNAL OF NEUROSCIENCE

Interleukin-1  and HMGB1 Mediate Hippocampal Dysfunction in SIGIRR-Deficient Mice

(2011) D. A. Costello et al.   JOURNAL OF NEUROSCIENCE

HMGB1 Acts on Microglia Mac1 to Mediate Chronic Neuroinflammation That Drives Progressive Neurodegeneration

(2011) H.-M. Gao et al.   JOURNAL OF NEUROSCIENCE

Hippocampal Focal Knockout of CBP Affects Specific Histone Modifications, Long-Term Potentiation and Long-Term Memory

(2011) Ruth M Barrett et al.   NEUROPSYCHOPHARMACOLOGY

Local Glutamate Level Dictates Adenosine A2A Receptor Regulation of Neuroinflammation and Traumatic Brain Injury

(2010) S. S. Dai et al.   JOURNAL OF NEUROSCIENCE

Chronic but not acute treatment with caffeine attenuates traumatic brain injury in the mouse cortical impact model

(2007) W. Li et al.   NEUROSCIENCE