NIR light-controlled mitochondria-targeted delivery of carbon monoxide combined with histone deacetylase inhibition for synergistic anticancer therapy

HDAC6-selective inhibitors enhance anticancer effects of paclitaxel in ovarian cancer cells

(2021) Jung Yoo et al.   Oncology Letters

Visible light-controlled carbon monoxide delivery combined with the inhibitory activity of histone deacetylases from a manganese complex for an enhanced antitumor therapy

(2021) Hai-Lin Zhang et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Novel dual-mode antitumor chlorin-based derivatives as potent photosensitizers and histone deacetylase inhibitors for photodynamic therapy and chemotherapy

(2021) Xing-Jie Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Ultrasound-Driven Biomimetic Nanosystem Suppresses Tumor Growth and Metastasis through Sonodynamic Therapy, CO Therapy, and Indoleamine 2,3-Dioxygenase Inhibition

(2020) Da Zhang et al.   ACS Nano

Histone Deacetylase Inhibitor Sensitizes ERCC1-High Non-small-Cell Lung Cancer Cells to Cisplatin via Regulating miR-149

(2020) Yuwen He et al.   Molecular Therapy-Oncolytics

Harnessing carbon monoxide-releasing platforms for cancer therapy

(2020) Yang Zhou et al.   BIOMATERIALS

HDAC3 inhibition up-regulates PD-L1 expression in B-cell lymphomas and augments the efficacy of anti-PD-L1 therapy

(2019) Siyu Deng et al.   MOLECULAR CANCER THERAPEUTICS

Immunoepigenetics Combination Therapies: An Overview of the Role of HDACs in Cancer Immunotherapy

(2019) Debarati Banik et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Thermal-Responsive Carbon Monoxide (CO) Delivery Expedites Metabolic Exhaustion of Cancer Cells toward Reversal of Chemotherapy Resistance

(2019) Yongjuan Li et al.   ACS Central Science

HDAC6 inhibition synergizes with anti-PD-L1 therapy in ARID1A-inactivated ovarian cancer.

(2019) Takeshi Fukumoto et al.   CANCER RESEARCH

Programmed ROS/CO-releasing nanomedicine for synergetic chemodynamic-gas therapy of cancer

(2019) Bin Zhao et al.   JOURNAL OF NANOBIOTECHNOLOGY

A New Histone Deacetylase Inhibitor Enhances Radiation Sensitivity through the Induction of Misfolded Protein Aggregation and Autophagy in Triple-Negative Breast Cancer

(2019) Hui-Wen Chiu et al.   Cancers

Combination Therapy With Histone Deacetylase Inhibitors (HDACi) for the Treatment of Cancer: Achieving the Full Therapeutic Potential of HDACi

(2018) Amila Suraweera et al.   Frontiers in Oncology

PDT-Driven Highly Efficient Intracellular Delivery and Controlled Release of CO in Combination with Sufficient Singlet Oxygen Production for Synergistic Anticancer Therapy

(2018) Lihuang Wu et al.   ADVANCED FUNCTIONAL MATERIALS

Recent Progress in Histone Deacetylase Inhibitors as Anticancer Agents

(2018) Loredana Cappellacci et al.   CURRENT MEDICINAL CHEMISTRY

On-demand CO release for amplification of chemotherapy by MOF functionalized magnetic carbon nanoparticles with NIR irradiation

(2018) Jizong Yao et al.   BIOMATERIALS

Radiosensitization In Vivo by Histone Deacetylase Inhibition with No Increase in Early Normal Tissue Radiation Toxicity

(2017) Blaz Groselj et al.   MOLECULAR CANCER THERAPEUTICS

Nitrogen and phosphorus co-doped graphene quantum dots as a nano-sensor for highly sensitive and selective imaging detection of nitrite in live cell

(2017) Rongjun Liu et al.   SENSORS AND ACTUATORS B-CHEMICAL

Light responsive metal–organic frameworks as controllable CO-releasing cell culture substrates

(2017) Stéphane Diring et al.   Chemical Science

Targeting Histone Deacetylases in Diseases: Where Are We?

(2015) Rosaria Benedetti et al.   ANTIOXIDANTS & REDOX SIGNALING

Synthesis and biological evaluation of novel histone deacetylases inhibitors with nitric oxide releasing activity

(2015) Wenwen Duan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A phosphorescent rhenium(i) histone deacetylase inhibitor: mitochondrial targeting and paraptosis induction

(2015) Rui-Rong Ye et al.   CHEMICAL COMMUNICATIONS

Rapid Eradication of Human Breast Cancer Cells through Trackable Light-Triggered CO Delivery by Mesoporous Silica Nanoparticles Packed with a Designed photoCORM

(2015) Indranil Chakraborty et al.   CHEMISTRY OF MATERIALS

Design, Synthesis, and Antitumor Evaluation of Novel Histone Deacetylase Inhibitors Equipped with a Phenylsulfonylfuroxan Module as a Nitric Oxide Donor

(2015) Wenwen Duan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Gasotransmitters in cancer: from pathophysiology to experimental therapy

(2015) Csaba Szabo   NATURE REVIEWS DRUG DISCOVERY

Cyclometalated Ir(iii) complexes as targeted theranostic anticancer therapeutics: combining HDAC inhibition with photodynamic therapy

(2014) Rui-Rong Ye et al.   CHEMICAL COMMUNICATIONS

Preparation of a Mitochondria-targeted and NO-Releasing Nanoplatform and its Enhanced Pro-Apoptotic Effect on Cancer Cells

(2014) Jiangsheng Xu et al.   Small

Carbon Monoxide Expedites Metabolic Exhaustion to Inhibit Tumor Growth

(2013) B. Wegiel et al.   CANCER RESEARCH

Inside HDAC with HDAC inhibitors

(2010) Philippe Bertrand   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and physiological significance

(2008) Chris E. Cooper et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Histone Deacetylase Inhibitors: From Bench to Clinic

(2008) Marielle Paris et al.   JOURNAL OF MEDICINAL CHEMISTRY