An NR2F1-specific agonist suppresses metastasis by inducing cancer cell dormancy

Translating the Science of Cancer Dormancy to the Clinic

(2021) Julio A. Aguirre-Ghiso   CANCER RESEARCH

Epigenetic therapy inhibits metastases by disrupting premetastatic niches

(2020) Zhihao Lu et al.   NATURE

mTOR at the nexus of nutrition, growth, ageing and disease

(2020) Grace Y. Liu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Inhibition of BET Proteins and Histone Deacetylase (HDACs): Crossing Roads in Cancer Therapy

(2019) Gloria Manzotti et al.   Cancers

Oral mucosal organoids as a potential platform for personalized cancer therapy

(2019) Else Driehuis et al.   Cancer Discovery

PI3K/AKT/mTOR signaling as a molecular target in head and neck cancer

(2019) Franziska E. Marquard et al.   BIOCHEMICAL PHARMACOLOGY

The pleiotropic transcriptional regulator COUP-TFI plays multiple roles in neural development and disease

(2018) Michele Bertacchi et al.   BRAIN RESEARCH

STAT3/p53 pathway activation disrupts IFN-β–induced dormancy in tumor-repopulating cells

(2018) Yuying Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Immunohistochemical detection of lymph node-DTCs in patients with node-negative HNSCC

(2017) Christoph Sproll et al.   INTERNATIONAL JOURNAL OF CANCER

Phenotypic heterogeneity of disseminated tumour cells is preset by primary tumour hypoxic microenvironments

(2017) Georg Fluegen et al.   NATURE CELL BIOLOGY

Salmon provides fast and bias-aware quantification of transcript expression

(2017) Rob Patro et al.   NATURE METHODS

Prognostic significance of the methylation of Wnt pathway antagonists—CXXC4, DACT2, and the inhibitors of sonic hedgehog signaling—ZIC1, ZIC4, and HHIP in head and neck squamous cell carcinomas

(2016) Jarosław Paluszczak et al.   Clinical Oral Investigations

Mer Tyrosine Kinase Regulates Disseminated Prostate Cancer Cellular Dormancy

(2016) Frank C. Cackowski et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Current Treatment Options for Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

(2015) Assuntina G. Sacco et al.   JOURNAL OF CLINICAL ONCOLOGY

NR2F1 controls tumour cell dormancy via SOX9- and RARβ-driven quiescence programmes

(2015) Maria Soledad Sosa et al.   Nature Communications

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

All trans-retinoic acid (ATRA) induces re-differentiation of early transformed breast epithelial cells

(2014) MARIA F. ARISI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

The Proliferation-Quiescence Decision Is Controlled by a Bifurcation in CDK2 Activity at Mitotic Exit

(2013) Sabrina L. Spencer et al.   CELL

TGF-β2 dictates disseminated tumour cell fate in target organs through TGF-β-RIII and p38α/β signalling

(2013) Paloma Bragado et al.   NATURE CELL BIOLOGY

The Gene Desert Mammary Carcinoma Susceptibility Locus Mcs1a Regulates Nr2f1 Modifying Mammary Epithelial Cell Differentiation and Proliferation

(2013) Bart M. G. Smits et al.   PLoS Genetics

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Epigenomic Annotation of Enhancers Predicts Transcriptional Regulators of Human Neural Crest

(2012) Alvaro Rada-Iglesias et al.   Cell Stem Cell

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Dormancy Signatures and Metastasis in Estrogen Receptor Positive and Negative Breast Cancer

(2012) Ryung S. Kim et al.   PLoS One

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

(2011) N. Stransky et al.   SCIENCE

Geminin Regulates Cortical Progenitor Proliferation and Differentiation

(2011) Magda Spella et al.   STEM CELLS

Assembling Neural Crest Regulatory Circuits into a Gene Regulatory Network

(2010) Paola Betancur et al.   Annual Review of Cell and Developmental Biology

Computational Identification of a p38SAPK-Regulated Transcription Factor Network Required for Tumor Cell Quiescence

(2009) A. P. Adam et al.   CANCER RESEARCH

Overexpression of COUP-TF1 in murine embryonic stem cells reduces retinoic acid-associated growth arrest and increases extraembryonic endoderm gene expression

(2008) Yong Zhuang et al.   DIFFERENTIATION

Identification of COUP-TFII Orphan Nuclear Receptor as a Retinoic Acid–Activated Receptor

(2008) Schoen W Kruse et al.   PLOS BIOLOGY