Review
Chemistry, Multidisciplinary
Yuchen Zhang, Shaoyang Ma, Jiaming Nie, Zhongbo Liu, Faming Chen, Ang Li, Dandan Pei
Summary: Bone mineralization is a complex process involving the interplay between organic and inorganic components of bone tissues. This review focuses on the evolution of mineral precursors in the bone mineralization process and highlights the tight control organisms have over each step. The connection between biomineralization and biomaterial design strategies is discussed, along with the detailed implementation of mineral precursor-based biomaterials in various bone graft materials.
Article
Chemistry, Multidisciplinary
Susrut Akkineni, Gregory S. Doerk, Chenyang Shi, Biao Jin, Shuai Zhang, Stefan Habelitz, James J. De Yoreo
Summary: The study demonstrates how the supramolecular structures of matrix proteins can be synthetically directed into predetermined patterns while retaining their functionality. They used block copolymer lamellar patterns to direct the assembly of peptide nanoribbons, which template calcium phosphate nucleation by creating a low-energy interface. The results show that the patterned nanoribbons maintain their structure and function, and successfully direct the formation of calcium phosphate with high fidelity.
Article
Chemistry, Multidisciplinary
Ouassef Nahi, Alexander N. Kulak, Shuheng Zhang, Xuefeng He, Zabeada Aslam, Martha A. Ilett, Ian J. Ford, Robert Darkins, Fiona C. Meldrum
Summary: This study demonstrates the remarkable control ability of cationic polyamines over the crystallization of calcium carbonate, promoting nucleation of aragonite at low concentrations and inhibiting its growth at high concentrations. The results reveal a mechanism of interaction between polyamines and magnesium ions that allows unprecedented control over aragonite formation.
Article
Chemistry, Multidisciplinary
Peiwen Liu, Jiaxiu Wang, Houjuan Qi, Tim Koddenberg, Dan Xu, Siyuan Liu, Kai Zhang
Summary: This study presents a novel method for self-assembly using chitin nanocrystals in capillaries. The fixed-boundary evaporation-induced self-assembly (FB-EISA) modality is employed, where a fixed air-liquid interface at the end of capillaries serves as the evaporation interface and initial deposition site of chitin nanocrystals. Through successive evaporation, continuous birefringent structures with a density gradient are generated, leading to the formation of cylindrical tubes.
Review
Biochemistry & Molecular Biology
Ricardo Villa-Bellosta
Summary: Cardiovascular complications due to accelerated arterial stiffening and atherosclerosis are the leading cause of morbimortality in Western society, often associated with vascular calcification. The balance between phosphate and pyrophosphate, strictly controlled by several genes, plays a key role in calcification.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Multidisciplinary
Rina Fujimaki, Yuya Oaki, Hiroaki Imai
Summary: Biomimetic strained SrSO4 crystals were produced through a nonclassical pathway involving fiber-by-fiber accumulation with poly(acrylic acid) in an aqueous solution system. Polymer-stabilized fibrous hydrate crystals were formed initially, followed by the formation of spindle-shaped microrods of SrSO4 through oriented attachment and dehydration. The structure of the anhydrous SrSO4 crystals resembles the biogenic SrSO4 spines of acantharian species.
Article
Chemistry, Multidisciplinary
Juxiang Yang, Daodao Hu, Wei Li, Yuan Jia, Pengna Li
Summary: Poly(N-isopropylacrylamide-co-acrylic acid)/copper sulfide composite microspheres with variable zigzag patterned surfaces were synthesized via biomimetic mineralization reaction, where the deposition amount and distribution of metal sulfide affect the surface morphology, leading to the deformation and shrinkage of surface texture.
Article
Chemistry, Multidisciplinary
Liang Shao, Shichang Liu, Guanying Li, Ye Zhang
Summary: In this study, a peptide self-assembled scaffold was proposed as an easily fabricated alternative to charged polymers for PILP templates. The scaffold formed phosphate-enriched nanofibrils by binding with multiple arginine residues via electrostatic interactions, assisting the mineralization of CaP. The resulting CaP mineralized scaffold exhibited good biocompatibility and tunable mechanical properties.
Review
Environmental Sciences
Linyu Deng, Bipro Ranjan Dhar
Summary: Phosphorus is an important element for human, animal, and plant life. The recovery of phosphorus from wastewater as calcium phosphate presents a low-cost and effective method, and the recovered CaP can be used as fertilizer and for other industrial applications. This review summarizes the effects of various factors on the precipitation/crystallization process and evaluates the efficiency and value proposition of recovered CaP. It also identifies process parameters for further optimization and provides perspectives on expanding the application field of recovered CaP.
Article
Biochemistry & Molecular Biology
Poowadon Chaiin, Jakarwan Yostaworakul, Chompoonut Rungnim, Pongtanawat Khemthong, Teerapong Yata, Suwimon Boonrungsiman
Summary: A nanoemulsion with specific surface properties can initiate the deposition of calcium phosphate on its surface, leading to formation of CaP nanoparticles with a lipid core. The lipid core can carry lipophilic compounds based on the function of the nanoemulsion, allowing for a dual purpose nanoemulsion of lipid nanoparticles exhibiting self-calcifying and carrier abilities.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
(2022)
Review
Chemistry, Multidisciplinary
Jingjing Han, Haoning Gong, Xiaokang Ren, Xuehai Yan
Summary: This article introduces the research field of peptide-based supramolecular nanozymes, emphasizing the importance and versatility of peptides as building blocks, as well as the potential for regulating catalytic performance.
Article
Chemistry, Physical
Jihye Lee, Adama Konate, Clement Guibert, Jessem Landoulsi
Summary: In this study, a biomimetic method for growing a hybrid calcium phosphate (CaP) - collagen coating is described. The versatility of layer-by-layer (LbL) method is explored to incorporate collagen and alkaline phosphatase (ALP), and control their organization and bioactivity. The presence of collagen fibrils in the LbL film plays a crucial role in the growth mechanism of the biomimetic mineral layer. The approach provides a straightforward way for designing biomimetic hybrid coatings in biomedical applications.
SURFACES AND INTERFACES
(2023)
Review
Polymer Science
Boyang Shi, Ding Shen, Wei Li, Guowei Wang
Summary: The self-assembly of copolymers containing crystallizable blocks in solution has gained increasing attention in recent years. Various strategies and advanced applications have been developed and explored. This review provides a comprehensive overview of the synthetic strategies, mechanisms, characteristics, and advanced applications of crystalline nano-assemblies in recent years, with the aim of promoting the development of self-assembly technology in interdisciplinary fields.
MACROMOLECULAR RAPID COMMUNICATIONS
(2022)
Article
Multidisciplinary Sciences
Hongtao Zhu, Eric Gouaux
Summary: The study presents the cryo-electron microscopy structures of native GlyRs, revealing a predominant subunit stoichiometry of 4 alpha:1 beta and unique structural features at the beta(+)-alpha(-) interface. The presence of a phenylalanine residue in the beta-subunit disrupts the canonical picrotoxin site, impacting receptor symmetry and ion channel pharmacology. Furthermore, incomplete receptor complexes and partially assembled alpha-trimers and alpha-tetramers are identified through structural elucidation.
Article
Biochemistry & Molecular Biology
Aya K. Cloyd, Kyle Boone, Qiang Ye, Malcolm L. Snead, Paulette Spencer, Candan Tamerler
Summary: Overcoming the short lifespan of current dental adhesives is a significant clinical need. Adhesives rely on the hybrid layer formation to adhere to dentin, but complete enclosure of demineralized collagen fibrils is currently unattainable. The use of peptide-based approach enables collagen intrafibrillar mineralization, providing a promising route for improving the long-term prospects of composite resins.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)